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Items: 1 to 20 of 132

1.

New 7-[4-(4-(un)substituted)piperazine-1-carbonyl]- piperazin-1-yl] derivatives of fluoroquinolone: synthesis and antimicrobial evaluation.

Chen PT, Lin WP, Lee AR, Hu MK.

Molecules. 2013 Jun 27;18(7):7557-69. doi: 10.3390/molecules18077557.

2.

Antistaphylococcal activities of the new fluoroquinolone JNJ-Q2.

Morrow BJ, Abbanat D, Baum EZ, Crespo-Carbone SM, Davies TA, He W, Shang W, Queenan AM, Lynch AS.

Antimicrob Agents Chemother. 2011 Dec;55(12):5512-21. doi: 10.1128/AAC.00470-11. Epub 2011 Sep 12.

3.

Synthesis and in vitro antibacterial activity of 7-(3-alkoxyimino-5-amino/methylaminopiperidin-1-yl)fluoroquinolone derivatives.

Zhang Y, Li G, Liu M, You X, Feng L, Lv K, Cao J, Guo H.

Bioorg Med Chem Lett. 2011 Feb 1;21(3):928-31. doi: 10.1016/j.bmcl.2010.12.073. Epub 2010 Dec 19.

PMID:
21232952
4.

Synthesis and in vitro antibacterial activity of 7-(3-alkoxyimino-4-methyl-4-methylaminopiperidin-1-yl)-fluoroquinolone derivatives.

Zhang YB, Feng LS, You XF, Guo Q, Guo HY, Liu ML.

Arch Pharm (Weinheim). 2010 Mar;343(3):143-51. doi: 10.1002/ardp.200900191.

PMID:
20186866
5.

JNJ-Q2, a new fluoroquinolone with potent in vitro activity against Staphylococcus aureus, including methicillin- and fluoroquinolone-resistant strains.

Farrell DJ, Liverman LC, Biedenbach DJ, Jones RN.

Antimicrob Agents Chemother. 2011 Jul;55(7):3631-4. doi: 10.1128/AAC.00162-11. Epub 2011 May 9.

6.

Design, synthesis and in vitro antibacterial activity of 7-(4-alkoxyimino-3-aminomethylpiperidin-1-yl)fluoroquinolone derivatives.

Chai Y, Wang J, Liu M, Yi H, Sun L, You X, Guo H.

Bioorg Med Chem Lett. 2011 Jun 1;21(11):3377-80. doi: 10.1016/j.bmcl.2011.04.002. Epub 2011 Apr 7.

PMID:
21515052
7.

Synthesis and in-vitro antibacterial activity of 7-(3-aminopyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivatives.

Guo X, Bai XG, Li YL, An ZJ, Xu LX, Han LY, Liu ML, Guo HY, Wang YC.

Arch Pharm (Weinheim). 2011 Aug;344(8):523-9. doi: 10.1002/ardp.201000160. Epub 2011 Jun 8.

PMID:
21656543
8.

Synergistic activity of 1-(1-naphthylmethyl)-piperazine with ciprofloxacin against clinically resistant Staphylococcus aureus, as determined by different methods.

Li L, Li Z, Guo N, Jin J, Du R, Liang J, Wu X, Wang X, Liu M, Jin Q, Yu L.

Lett Appl Microbiol. 2011 Apr;52(4):372-8. doi: 10.1111/j.1472-765X.2011.03010.x. Epub 2011 Feb 10.

9.

In vitro antibacterial activities of JNJ-Q2, a new broad-spectrum fluoroquinolone.

Morrow BJ, He W, Amsler KM, Foleno BD, Macielag MJ, Lynch AS, Bush K.

Antimicrob Agents Chemother. 2010 May;54(5):1955-64. doi: 10.1128/AAC.01374-09. Epub 2010 Feb 22.

11.

Synthesis and biological evaluation of novel benzothiazole clubbed fluoroquinolone derivatives.

Sharma PC, Kumar R, Chaudhary M, Sharma A, Rajak H.

J Enzyme Inhib Med Chem. 2013 Feb;28(1):1-10. doi: 10.3109/14756366.2011.611943. Epub 2011 Oct 10.

PMID:
21981002
12.

Synthesis and in vitro antibacterial activity of 7-(4-alkoxyimino-3-amino-3-methylpiperidin-1-yl)fluoroquinolone derivatives.

Chai Y, Wan ZL, Wang B, Guo HY, Liu ML.

Eur J Med Chem. 2009 Oct;44(10):4063-9. doi: 10.1016/j.ejmech.2009.04.041. Epub 2009 May 8.

PMID:
19481308
13.

[Susceptibility of 570 Pseudomonas aeruginosa strains to 11 antimicrobial agents and the mechanism of its resistance to fluoroquinolones].

Lei YC, Wang HB, Sun ZY, Shen ZY.

Zhonghua Yi Xue Za Zhi. 2003 Mar 10;83(5):403-7. Chinese.

PMID:
12820918
14.

Synthesis and antibacterial activity of new fluoroquinolones containing a substituted N-(phenethyl)piperazine moiety.

Foroumadi A, Ghodsi S, Emami S, Najjari S, Samadi N, Faramarzi MA, Beikmohammadi L, Shirazi FH, Shafiee A.

Bioorg Med Chem Lett. 2006 Jul 1;16(13):3499-503. Epub 2006 Apr 27.

PMID:
16644219
15.

Discovery of the highly potent fluoroquinolone-based benzothiazolyl-4-thiazolidinone hybrids as antibacterials.

Patel RV, Park SW.

Chem Biol Drug Des. 2014 Jul;84(1):123-9. doi: 10.1111/cbdd.12299. Epub 2014 May 19.

PMID:
24524270
16.

Synthesis and in vitro antibacterial activity of novel fluoroquinolone derivatives containing substituted piperidines.

Chai Y, Liu M, Wang B, You X, Feng L, Zhang Y, Cao J, Guo H.

Bioorg Med Chem Lett. 2010 Sep 1;20(17):5195-8. doi: 10.1016/j.bmcl.2010.07.006. Epub 2010 Jul 8.

PMID:
20667731
17.

Varying fitness cost associated with resistance to fluoroquinolones governs clonal dynamic of methicillin-resistant Staphylococcus aureus.

Horváth A, Dobay O, Kardos S, Ghidán Á, Tóth Á, Pászti J, Ungvári E, Horváth P, Nagy K, Zissman S, Füzi M.

Eur J Clin Microbiol Infect Dis. 2012 Aug;31(8):2029-36. doi: 10.1007/s10096-011-1536-z. Epub 2012 Jan 5.

PMID:
22218830
18.

4-Substituted 4-(1H-1,2,3-triazol-1-yl)piperidine: novel C7 moieties of fluoroquinolones as antibacterial agents.

Huang X, Zhang A, Chen D, Jia Z, Li X.

Bioorg Med Chem Lett. 2010 May 1;20(9):2859-63. doi: 10.1016/j.bmcl.2010.03.044. Epub 2010 Mar 12.

PMID:
20347299
19.

Synthesis and in vitro antibacterial activity of 7-(3-alkoxyimino-4-amino-4-methylpiperidin-1-yl) fluoroquinolone derivatives.

Wang JX, Zhang YB, Liu ML, Wang B, Chai Y, Li SJ, Guo HY.

Eur J Med Chem. 2011 Jun;46(6):2421-6. doi: 10.1016/j.ejmech.2011.03.026. Epub 2011 Mar 23.

PMID:
21481984
20.

Dichotomous selection of high-level oxacillin resistance in Staphylococcus aureus by fluoroquinolones.

Dalhoff A, Schubert S.

Int J Antimicrob Agents. 2010 Sep;36(3):216-21. doi: 10.1016/j.ijantimicag.2010.04.014. Epub 2010 Jul 14.

PMID:
20630710

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