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Items: 1 to 20 of 107

1.

ERK1/2 regulates SIRT2 deacetylase activity.

Choi YH, Kim H, Lee SH, Jin YH, Lee KY.

Biochem Biophys Res Commun. 2013 Jul 26;437(2):245-9. doi: 10.1016/j.bbrc.2013.06.053. Epub 2013 Jun 24.

PMID:
23806683
2.

Src regulates the activity of SIRT2.

Choi YH, Kim H, Lee SH, Jin YH, Lee KY.

Biochem Biophys Res Commun. 2014 Jul 25;450(2):1120-5. doi: 10.1016/j.bbrc.2014.06.117. Epub 2014 Jul 1.

PMID:
24996174
3.

Cbl regulates the activity of SIRT2.

Choi YH, Kim H, Han Y, Jin YH, Lee KY.

Biochem Biophys Res Commun. 2014 Oct 24;453(3):557-62. doi: 10.1016/j.bbrc.2014.09.125. Epub 2014 Oct 5.

PMID:
25285640
4.

SIRT2 mediates multidrug resistance in acute myelogenous leukemia cells via ERK1/2 signaling pathway.

Xu H, Li Y, Chen L, Wang C, Wang Q, Zhang H, Lin Y, Li Q, Pang T.

Int J Oncol. 2016 Feb;48(2):613-23. doi: 10.3892/ijo.2015.3275. Epub 2015 Dec 7.

PMID:
26647771
5.

Osterix is regulated by Erk1/2 during osteoblast differentiation.

Choi YH, Gu YM, Oh JW, Lee KY.

Biochem Biophys Res Commun. 2011 Nov 25;415(3):472-8. doi: 10.1016/j.bbrc.2011.10.097. Epub 2011 Oct 28.

PMID:
22056560
6.

Sirt2 interacts with 14-3-3 beta/gamma and down-regulates the activity of p53.

Jin YH, Kim YJ, Kim DW, Baek KH, Kang BY, Yeo CY, Lee KY.

Biochem Biophys Res Commun. 2008 Apr 11;368(3):690-5. doi: 10.1016/j.bbrc.2008.01.114. Epub 2008 Feb 4.

PMID:
18249187
7.

SIRT2 regulates NF-κB dependent gene expression through deacetylation of p65 Lys310.

Rothgiesser KM, Erener S, Waibel S, Lüscher B, Hottiger MO.

J Cell Sci. 2010 Dec 15;123(Pt 24):4251-8. doi: 10.1242/jcs.073783. Epub 2010 Nov 16.

8.

Acetylation of Sirt2 by p300 attenuates its deacetylase activity.

Han Y, Jin YH, Kim YJ, Kang BY, Choi HJ, Kim DW, Yeo CY, Lee KY.

Biochem Biophys Res Commun. 2008 Oct 31;375(4):576-80. doi: 10.1016/j.bbrc.2008.08.042. Epub 2008 Aug 21.

PMID:
18722353
9.

SIRT2 Regulates LPS-Induced Renal Tubular CXCL2 and CCL2 Expression.

Jung YJ, Lee AS, Nguyen-Thanh T, Kim D, Kang KP, Lee S, Park SK, Kim W.

J Am Soc Nephrol. 2015 Jul;26(7):1549-60. doi: 10.1681/ASN.2014030226. Epub 2014 Oct 27.

11.

Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf.

Marzec M, Kasprzycka M, Liu X, Raghunath PN, Wlodarski P, Wasik MA.

Oncogene. 2007 Feb 8;26(6):813-21. Epub 2006 Aug 7.

PMID:
16909118
12.
13.

SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis.

Li Y, Matsumori H, Nakayama Y, Osaki M, Kojima H, Kurimasa A, Ito H, Mori S, Katoh M, Oshimura M, Inoue T.

Genes Cells. 2011 Jan;16(1):34-45. doi: 10.1111/j.1365-2443.2010.01460.x. Epub 2010 Nov 9.

14.
15.

Molecular modeling study for conformational changes of Sirtuin 2 due to substrate and inhibitor binding.

Sakkiah S, Chandrasekaran M, Lee Y, Kim S, Lee KW.

J Biomol Struct Dyn. 2012;30(3):235-54. doi: 10.1080/07391102.2012.680026. Epub 2012 Jun 12.

PMID:
22694102
16.

Regulation of the mitogen-activated protein kinase kinase (MEK)-1 by NAD(+)-dependent deacetylases.

Yeung F, Ramsey CS, Popko-Scibor AE, Allison DF, Gray LG, Shin M, Kumar M, Li D, McCubrey JA, Mayo MW.

Oncogene. 2015 Feb 5;34(6):798-804. doi: 10.1038/onc.2014.39. Epub 2014 Mar 31.

17.

The NAD-dependent deacetylase SIRT2 is required for programmed necrosis.

Narayan N, Lee IH, Borenstein R, Sun J, Wong R, Tong G, Fergusson MM, Liu J, Rovira II, Cheng HL, Wang G, Gucek M, Lombard D, Alt FW, Sack MN, Murphy E, Cao L, Finkel T.

Nature. 2012 Dec 13;492(7428):199-204. doi: 10.1038/nature11700. Epub 2012 Nov 28. Retraction in: Nature. 2014 Feb 27;506(7489):516.

PMID:
23201684
18.

Insight the C-site pocket conformational changes responsible for sirtuin 2 activity using molecular dynamics simulations.

Sakkiah S, Arooj M, Cao GP, Lee KW.

PLoS One. 2013;8(3):e59278. doi: 10.1371/journal.pone.0059278. Epub 2013 Mar 20.

19.

Sirt2 is a novel in vivo downstream target of Nkx2.2 and enhances oligodendroglial cell differentiation.

Ji S, Doucette JR, Nazarali AJ.

J Mol Cell Biol. 2011 Dec;3(6):351-9. doi: 10.1093/jmcb/mjr009. Epub 2011 Jun 13.

PMID:
21669943
20.

Activation of ERK mitogen-activated protein kinase in human cells by the mycotoxin patulin.

Wu TS, Yu FY, Su CC, Kan JC, Chung CP, Liu BH.

Toxicol Appl Pharmacol. 2005 Sep 1;207(2):103-11.

PMID:
16102563

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