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Oct4: the final frontier, differentiation defining pluripotency.

Livigni A, Brickman JM.

Dev Cell. 2013 Jun 24;25(6):547-8. doi: 10.1016/j.devcel.2013.06.002.


Oct4 cell-autonomously promotes primitive endoderm development in the mouse blastocyst.

Frum T, Halbisen MA, Wang C, Amiri H, Robson P, Ralston A.

Dev Cell. 2013 Jun 24;25(6):610-22. doi: 10.1016/j.devcel.2013.05.004. Epub 2013 Jun 6.


OCT4 Coordinates with WNT Signaling to Pre-pattern Chromatin at the SOX17 Locus during Human ES Cell Differentiation into Definitive Endoderm.

Ying L, Mills JA, French DL, Gadue P.

Stem Cell Reports. 2015 Oct 13;5(4):490-8. doi: 10.1016/j.stemcr.2015.08.014. Epub 2015 Sep 24.


A membrane-associated β-catenin/Oct4 complex correlates with ground-state pluripotency in mouse embryonic stem cells.

Faunes F, Hayward P, Descalzo SM, Chatterjee SS, Balayo T, Trott J, Christoforou A, Ferrer-Vaquer A, Hadjantonakis AK, Dasgupta R, Arias AM.

Development. 2013 Mar;140(6):1171-83. doi: 10.1242/dev.085654.


Functional similarities among genes regulated by OCT4 in human mesenchymal and embryonic stem cells.

Greco SJ, Liu K, Rameshwar P.

Stem Cells. 2007 Dec;25(12):3143-54. Epub 2007 Aug 30.


[Expression patterns of germ line specific genes in mouse and human pluripotent stem cells are associated with regulation of ground and primed state of pluripotency].

Gordeev OF, Lifantseva NV, Khaĭdukov SV.

Ontogenez. 2011 Nov-Dec;42(6):403-24. Russian. Erratum in: Ontogenez. 2014 Mar-Apr;45(2):129.


Oct4 expression in in-vitro-produced sheep blastocysts and embryonic-stem-like cells.

Sanna D, Sanna A, Mara L, Pilichi S, Mastinu A, Chessa F, Pani L, Dattena M.

Cell Biol Int. 2009 Dec 16;34(1):53-60. doi: 10.1042/CBI20090008.


A novel and critical role for Oct4 as a regulator of the maternal-embryonic transition.

Foygel K, Choi B, Jun S, Leong DE, Lee A, Wong CC, Zuo E, Eckart M, Reijo Pera RA, Wong WH, Yao MW.

PLoS One. 2008;3(12):e4109. doi: 10.1371/journal.pone.0004109. Epub 2008 Dec 31.


Development: sketch for a theory of Oct4.

Wagner RT, Zwaka TP.

Curr Biol. 2013 Nov 18;23(22):R1014-6. doi: 10.1016/j.cub.2013.10.003.


Actl6a protects embryonic stem cells from differentiating into primitive endoderm.

Lu W, Fang L, Ouyang B, Zhang X, Zhan S, Feng X, Bai Y, Han X, Kim H, He Q, Wan M, Shi FT, Feng XH, Liu D, Huang J, Songyang Z.

Stem Cells. 2015 Jun;33(6):1782-93. doi: 10.1002/stem.2000.


Concise review: isoforms of OCT4 contribute to the confusing diversity in stem cell biology.

Wang X, Dai J.

Stem Cells. 2010 May;28(5):885-93. doi: 10.1002/stem.419. Review.


Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells.

Wamaitha SE, del Valle I, Cho LT, Wei Y, Fogarty NM, Blakeley P, Sherwood RI, Ji H, Niakan KK.

Genes Dev. 2015 Jun 15;29(12):1239-55. doi: 10.1101/gad.257071.114.


[The dual role of OCT4].

Stefanovic S, Pucéat M.

Med Sci (Paris). 2010 Apr;26(4):411-6. doi: 10.1051/medsci/2010264411. Review. French.


The primitive endoderm segregates from the epiblast in β1 integrin-deficient early mouse embryos.

Moore R, Tao W, Smith ER, Xu XX.

Mol Cell Biol. 2014 Feb;34(3):560-72. doi: 10.1128/MCB.00937-13. Epub 2013 Nov 25.


Medaka Oct4 is essential for pluripotency in blastula formation and ES cell derivation.

Liu R, Li M, Li Z, Hong N, Xu H, Hong Y.

Stem Cell Rev. 2015 Feb;11(1):11-23. doi: 10.1007/s12015-014-9523-2.


Dynamic GATA6 expression in primitive endoderm formation and maturation in early mouse embryogenesis.

Cai KQ, Capo-Chichi CD, Rula ME, Yang DH, Xu XX.

Dev Dyn. 2008 Oct;237(10):2820-9. doi: 10.1002/dvdy.21703.


Stk40 links the pluripotency factor Oct4 to the Erk/MAPK pathway and controls extraembryonic endoderm differentiation.

Li L, Sun L, Gao F, Jiang J, Yang Y, Li C, Gu J, Wei Z, Yang A, Lu R, Ma Y, Tang F, Kwon SW, Zhao Y, Li J, Jin Y.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1402-7. doi: 10.1073/pnas.0905657107. Epub 2010 Jan 4.


Adipocyte differentiation in human embryonic stem cells transduced with Oct4 shRNA lentivirus.

Hannan NR, Wolvetang EJ.

Stem Cells Dev. 2009 May;18(4):653-60. doi: 10.1089/scd.2008.0160.


Derivation of high-purity definitive endoderm from human parthenogenetic stem cells using an in vitro analog of the primitive streak.

Turovets N, Fair J, West R, Ostrowska A, Semechkin R, Janus J, Cui L, Agapov V, Turovets I, Semechkin A, Csete M, Agapova L.

Cell Transplant. 2012;21(1):217-34. doi: 10.3727/096368911X582723. Epub 2011 Jun 9.


LIF supports primitive endoderm expansion during pre-implantation development.

Morgani SM, Brickman JM.

Development. 2015 Oct 15;142(20):3488-99. doi: 10.1242/dev.125021. Epub 2015 Sep 22.

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