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Items: 1 to 20 of 105

1.

Two Distinct Categories of Focal Deletions in Cancer Genomes.

Rajaram M, Zhang J, Wang T, Li J, Kuscu C, Qi H, Kato M, Grubor V, Weil RJ, Helland A, Borrenson-Dale AL, Cho KR, Levine DA, Houghton AN, Wolchok JD, Myeroff L, Markowitz SD, Lowe SW, Zhang M, Krasnitz A, Lucito R, Mu D, Powers RS.

PLoS One. 2013 Jun 21;8(6):e66264. doi: 10.1371/journal.pone.0066264. Print 2013.

2.

Common fragile sites, extremely large genes, neural development and cancer.

Smith DI, Zhu Y, McAvoy S, Kuhn R.

Cancer Lett. 2006 Jan 28;232(1):48-57. Epub 2005 Oct 10. Review.

PMID:
16221525
3.

Common fragile site profiling in epithelial and erythroid cells reveals that most recurrent cancer deletions lie in fragile sites hosting large genes.

Le Tallec B, Millot GA, Blin ME, Brison O, Dutrillaux B, Debatisse M.

Cell Rep. 2013 Aug 15;4(3):420-8. doi: 10.1016/j.celrep.2013.07.003. Epub 2013 Aug 1.

4.

Replication stress induces tumor-like microdeletions in FHIT/FRA3B.

Durkin SG, Ragland RL, Arlt MF, Mulle JG, Warren ST, Glover TW.

Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):246-51. Epub 2007 Dec 27.

5.

Disabled-1 is a large common fragile site gene, inactivated in multiple cancers.

McAvoy S, Zhu Y, Perez DS, James CD, Smith DI.

Genes Chromosomes Cancer. 2008 Feb;47(2):165-74.

PMID:
18008369
6.

Tumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage Response.

Hazan I, Hofmann TG, Aqeilan RI.

PLoS Genet. 2016 Dec 15;12(12):e1006436. doi: 10.1371/journal.pgen.1006436. eCollection 2016 Dec. Review.

7.

The FRA2C common fragile site maps to the borders of MYCN amplicons in neuroblastoma and is associated with gross chromosomal rearrangements in different cancers.

Blumrich A, Zapatka M, Brueckner LM, Zheglo D, Schwab M, Savelyeva L.

Hum Mol Genet. 2011 Apr 15;20(8):1488-501. doi: 10.1093/hmg/ddr027. Epub 2011 Jan 21.

PMID:
21258086
8.

Molecular characterization of FRAXB and comparative common fragile site instability in cancer cells.

Arlt MF, Miller DE, Beer DG, Glover TW.

Genes Chromosomes Cancer. 2002 Jan;33(1):82-92.

9.

A selected group of large common fragile site genes have decreased expression in oropharyngeal squamous cell carcinomas.

Gao G, Kasperbauer JL, Tombers NM, Wang V, Mayer K, Smith DI.

Genes Chromosomes Cancer. 2014 May;53(5):392-401. doi: 10.1002/gcc.22150. Epub 2014 Jan 31.

PMID:
24481768
10.

WWOX, large common fragile site genes, and cancer.

Gao G, Smith DI.

Exp Biol Med (Maywood). 2015 Mar;240(3):285-95. doi: 10.1177/1535370214565992. Epub 2015 Jan 16. Review.

12.

DMD and IL1RAPL1: two large adjacent genes localized within a common fragile site (FRAXC) have reduced expression in cultured brain tumors.

McAvoy S, Ganapathiraju S, Perez DS, James CD, Smith DI.

Cytogenet Genome Res. 2007;119(3-4):196-203. doi: 10.1159/000112061. Epub 2008 Feb 1.

PMID:
18253029
13.

Investigation of tumor suppressor genes apart from VHL on 3p by deletion mapping in sporadic clear cell renal cell carcinoma (cRCC).

Singh RB, Amare Kadam PS.

Urol Oncol. 2013 Oct;31(7):1333-42. doi: 10.1016/j.urolonc.2011.08.012. Epub 2011 Oct 1.

PMID:
21962529
14.

Non-random inactivation of large common fragile site genes in different cancers.

McAvoy S, Ganapathiraju SC, Ducharme-Smith AL, Pritchett JR, Kosari F, Perez DS, Zhu Y, James CD, Smith DI.

Cytogenet Genome Res. 2007;118(2-4):260-9. Review.

PMID:
18000379
15.

A novel approach to simultaneously scan genes at fragile sites.

Willem P, Brown J, Schouten J.

BMC Cancer. 2006 Aug 8;6:205.

16.

A survey of homozygous deletions in human cancer genomes.

Cox C, Bignell G, Greenman C, Stabenau A, Warren W, Stephens P, Davies H, Watt S, Teague J, Edkins S, Birney E, Easton DF, Wooster R, Futreal PA, Stratton MR.

Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4542-7. Epub 2005 Mar 10.

17.

Instability at the FRA8I common fragile site disrupts the genomic integrity of the KIAA0146, CEBPD and PRKDC genes in colorectal cancer.

Brueckner LM, Hess EM, Schwab M, Savelyeva L.

Cancer Lett. 2013 Aug 9;336(1):85-95. doi: 10.1016/j.canlet.2013.04.007. Epub 2013 Apr 16.

PMID:
23603433
18.

Common fragile sites (CFS) and extremely large CFS genes are targets for human papillomavirus integrations and chromosome rearrangements in oropharyngeal squamous cell carcinoma.

Gao G, Johnson SH, Vasmatzis G, Pauley CE, Tombers NM, Kasperbauer JL, Smith DI.

Genes Chromosomes Cancer. 2017 Jan;56(1):59-74. doi: 10.1002/gcc.22415. Epub 2016 Nov 1.

PMID:
27636103
19.

Signatures of mutation and selection in the cancer genome.

Bignell GR, Greenman CD, Davies H, Butler AP, Edkins S, Andrews JM, Buck G, Chen L, Beare D, Latimer C, Widaa S, Hinton J, Fahey C, Fu B, Swamy S, Dalgliesh GL, Teh BT, Deloukas P, Yang F, Campbell PJ, Futreal PA, Stratton MR.

Nature. 2010 Feb 18;463(7283):893-8. doi: 10.1038/nature08768.

20.

WWOX: a fragile tumor suppressor.

Schrock MS, Huebner K.

Exp Biol Med (Maywood). 2015 Mar;240(3):296-304. doi: 10.1177/1535370214561590. Epub 2014 Dec 22. Review.

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