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Relationship between diet and plasma long-chain n-3 PUFAs in older people: impact of apolipoprotein E genotype.

Samieri C, Lorrain S, Buaud B, Vaysse C, Berr C, Peuchant E, Cunnane SC, Barberger-Gateau P.

J Lipid Res. 2013 Sep;54(9):2559-67. doi: 10.1194/jlr.P036475. Epub 2013 Jun 25.


Interaction between BMI and APOE genotype is associated with changes in the plasma long-chain-PUFA response to a fish-oil supplement in healthy participants.

Chouinard-Watkins R, Conway V, Minihane AM, Jackson KG, Lovegrove JA, Plourde M.

Am J Clin Nutr. 2015 Aug;102(2):505-13. doi: 10.3945/ajcn.114.103507. Epub 2015 Jun 17.


A Diet Rich in Docosahexaenoic Acid Restores Liver Arachidonic Acid and Docosahexaenoic Acid Concentrations in Mice Homozygous for the Human Apolipoprotein E ε4 Allele.

Chouinard-Watkins R, Pinçon A, Coulombe JD, Spencer R, Massenavette L, Plourde M.

J Nutr. 2016 Jul;146(7):1315-21. doi: 10.3945/jn.116.230052. Epub 2016 Jun 15.


A Taiwanese food frequency questionnaire correlates with plasma docosahexaenoic acid but not with plasma eicosapentaenoic acid levels: questionnaires and plasma biomarkers.

Chien KL, Lee MS, Tsai YT, Chen PR, Lin HJ, Hsu HC, Lee YT, Chen MF.

BMC Med Res Methodol. 2013 Feb 16;13:23. doi: 10.1186/1471-2288-13-23.


Omega-3 dietary Fatty Acid status of healthy older adults in Tasmania, Australia: an observational study.

Pittaway JK, Chuang LT, Ahuja KD, Beckett JM, Glew RH, Ball MJ.

J Nutr Health Aging. 2015 May;19(5):505-10. doi: 10.1007/s12603-015-0459-2.


Impact of Genotype on EPA and DHA Status and Responsiveness to Increased Intakes.

Minihane AM.

Nutrients. 2016 Mar 2;8(3):123. doi: 10.3390/nu8030123. Review.


Postprandial enrichment of triacylglycerol-rich lipoproteins with omega-3 fatty acids: lack of an interaction with apolipoprotein E genotype?

Conway V, Allard MJ, Minihane AM, Jackson KG, Lovegrove JA, Plourde M.

Lipids Health Dis. 2014 Sep 16;13:148. doi: 10.1186/1476-511X-13-148.


Plasma n-3 fatty acid response to an n-3 fatty acid supplement is modulated by apoE epsilon4 but not by the common PPAR-alpha L162V polymorphism in men.

Plourde M, Vohl MC, Vandal M, Couture P, Lemieux S, Cunnane SC.

Br J Nutr. 2009 Oct;102(8):1121-4. doi: 10.1017/S000711450938215X.


Incorporation of eicosapentaenioic and docosahexaenoic acids into breast adipose tissue of women at high risk of breast cancer: a randomized clinical trial of dietary fish and n-3 fatty acid capsules.

Straka S, Lester JL, Cole RM, Andridge RR, Puchala S, Rose AM, Clinton SK, Belury MA, Yee LD.

Mol Nutr Food Res. 2015 Sep;59(9):1780-90. doi: 10.1002/mnfr.201500161. Epub 2015 Jul 7.


Reduction in DHA transport to the brain of mice expressing human APOE4 compared to APOE2.

Vandal M, Alata W, Tremblay C, Rioux-Perreault C, Salem N Jr, Calon F, Plourde M.

J Neurochem. 2014 May;129(3):516-26. doi: 10.1111/jnc.12640. Epub 2014 Jan 29.


Disrupted fatty acid distribution in HDL and LDL according to apolipoprotein E allele.

Dang TM, Conway V, Plourde M.

Nutrition. 2015 Jun;31(6):807-12. doi: 10.1016/j.nut.2014.11.019. Epub 2014 Dec 24.


Similar eicosapentaenoic acid and docosahexaenoic acid plasma levels achieved with fish oil or krill oil in a randomized double-blind four-week bioavailability study.

Yurko-Mauro K, Kralovec J, Bailey-Hall E, Smeberg V, Stark JG, Salem N Jr.

Lipids Health Dis. 2015 Sep 2;14:99. doi: 10.1186/s12944-015-0109-z.


Alcohol consumption and n-3 polyunsaturated fatty acids in healthy men and women from 3 European populations.

di Giuseppe R, de Lorgeril M, Salen P, Laporte F, Di Castelnuovo A, Krogh V, Siani A, Arnout J, Cappuccio FP, van Dongen M, Donati MB, de Gaetano G, Iacoviello L; European Collaborative Group of the IMMIDIET Project..

Am J Clin Nutr. 2009 Jan;89(1):354-62. doi: 10.3945/ajcn.2008.26661. Epub 2008 Dec 3.


Effect of sex and genotype on cardiovascular biomarker response to fish oils: the FINGEN Study.

Caslake MJ, Miles EA, Kofler BM, Lietz G, Curtis P, Armah CK, Kimber AC, Grew JP, Farrell L, Stannard J, Napper FL, Sala-Vila A, West AL, Mathers JC, Packard C, Williams CM, Calder PC, Minihane AM.

Am J Clin Nutr. 2008 Sep;88(3):618-29.


Long-chain n-3 polyunsaturated fatty acid dietary recommendations are moderately efficient in optimizing their status in healthy middle-aged subjects with low fish consumption: a cross-over study.

Djuricic ID, Mazic SD, Kotur-Stevuljevic JM, Djordjevic VR, Sobajic SS.

Nutr Res. 2014 Mar;34(3):210-8. doi: 10.1016/j.nutres.2013.12.008. Epub 2014 Jan 3.


Ethnicity, plasma phospholipid fatty acid composition and inflammatory/endothelial activation biomarkers in the Multi-Ethnic Study of Atherosclerosis (MESA).

Steffen BT, Steffen LM, Tracy R, Siscovick D, Jacobs D, Liu K, He K, Hanson NQ, Nettleton JA, Tsai MY.

Eur J Clin Nutr. 2012 May;66(5):600-5. doi: 10.1038/ejcn.2011.215. Epub 2012 Jan 4.


Effect of fish oils containing different amounts of EPA, DHA, and antioxidants on plasma and brain fatty acids and brain nitric oxide synthase activity in rats.

Engström K, Saldeen AS, Yang B, Mehta JL, Saldeen T.

Ups J Med Sci. 2009;114(4):206-13. doi: 10.3109/03009730903268958.


A practical approach to increasing intakes of n-3 polyunsaturated fatty acids: use of novel foods enriched with n-3 fats.

Metcalf RG, James MJ, Mantzioris E, Cleland LG.

Eur J Clin Nutr. 2003 Dec;57(12):1605-12.


Increased selenium intake in elderly high fish consumers may account for health benefits previously ascribed to omega-3 fatty acids.

Berr C, Akbaraly T, Arnaud J, Hininger I, Roussel AM, Barberger Gateau P.

J Nutr Health Aging. 2009 Jan;13(1):14-8.


Contribution of apolipoprotein E genotype and docosahexaenoic acid to the LDL-cholesterol response to fish oil.

Olano-Martin E, Anil E, Caslake MJ, Packard CJ, Bedford D, Stewart G, Peiris D, Williams CM, Minihane AM.

Atherosclerosis. 2010 Mar;209(1):104-10. doi: 10.1016/j.atherosclerosis.2009.08.024. Epub 2009 Aug 21.


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