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Items: 1 to 20 of 88

1.

Critical differences between isoforms of securin reveal mechanisms of separase regulation.

Han X, Poon RY.

Mol Cell Biol. 2013 Sep;33(17):3400-15. doi: 10.1128/MCB.00057-13. Epub 2013 Jun 24.

2.

Regulation of human separase by securin binding and autocleavage.

Waizenegger I, Giménez-Abián JF, Wernic D, Peters JM.

Curr Biol. 2002 Aug 20;12(16):1368-78.

4.

Drosophila separase is required for sister chromatid separation and binds to PIM and THR.

Jäger H, Herzig A, Lehner CF, Heidmann S.

Genes Dev. 2001 Oct 1;15(19):2572-84.

5.

A single mutation in Securin induces chromosomal instability and enhances cell invasion.

Mora-Santos M, Castilla C, Herrero-Ruiz J, Giráldez S, Limón-Mortés MC, Sáez C, Japón MÁ, Tortolero M, Romero F.

Eur J Cancer. 2013 Jan;49(2):500-10. doi: 10.1016/j.ejca.2012.06.024. Epub 2012 Jul 18.

PMID:
22819078
6.

Protein phosphatase 2A and separase form a complex regulated by separase autocleavage.

Holland AJ, Böttger F, Stemmann O, Taylor SS.

J Biol Chem. 2007 Aug 24;282(34):24623-32. Epub 2007 Jun 29.

7.

Nuclear exclusion of separase prevents cohesin cleavage in interphase cells.

Sun Y, Yu H, Zou H.

Cell Cycle. 2006 Nov 1;5(21):2537-42. Epub 2006 Sep 13.

PMID:
17102637
8.

Securin and separase phosphorylation act redundantly to maintain sister chromatid cohesion in mammalian cells.

Huang X, Hatcher R, York JP, Zhang P.

Mol Biol Cell. 2005 Oct;16(10):4725-32. Epub 2005 Jul 19.

9.
10.

Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression.

Wirth KG, Wutz G, Kudo NR, Desdouets C, Zetterberg A, Taghybeeglu S, Seznec J, Ducos GM, Ricci R, Firnberg N, Peters JM, Nasmyth K.

J Cell Biol. 2006 Mar 13;172(6):847-60.

11.
12.

Mutual inhibition of separase and Cdk1 by two-step complex formation.

Gorr IH, Boos D, Stemmann O.

Mol Cell. 2005 Jul 1;19(1):135-41.

13.

PTTG2 silencing results in induction of epithelial-to-mesenchymal transition and apoptosis.

Méndez-Vidal C, Gámez-Del Estal MM, Moreno-Mateos MA, Espina-Zambrano AG, Torres B, Pintor-Toro JA.

Cell Death Dis. 2013 Mar 7;4:e530. doi: 10.1038/cddis.2013.48.

14.

Cyclin-B1-mediated inhibition of excess separase is required for timely chromosome disjunction.

Holland AJ, Taylor SS.

J Cell Sci. 2006 Aug 15;119(Pt 16):3325-36. Epub 2006 Jul 25.

15.

Securin and separase modulate membrane traffic by affecting endosomal acidification.

Bacac M, Fusco C, Planche A, Santodomingo J, Demaurex N, Leemann-Zakaryan R, Provero P, Stamenkovic I.

Traffic. 2011 May;12(5):615-26. doi: 10.1111/j.1600-0854.2011.01169.x. Epub 2011 Feb 25.

16.

Separase, securin and Rad21 in neural cell growth.

Pemberton HN, Franklyn JA, Boelaert K, Chan SY, Kim DS, Kim C, Cheng SY, Kilby MD, McCabe CJ.

J Cell Physiol. 2007 Oct;213(1):45-53.

PMID:
17450531
17.

Overexpression of the pituitary tumor transforming gene induces p53-dependent senescence through activating DNA damage response pathway in normal human fibroblasts.

Hsu YH, Liao LJ, Yu CH, Chiang CP, Jhan JR, Chang LC, Chen YJ, Lou PJ, Lin JJ.

J Biol Chem. 2010 Jul 16;285(29):22630-8. doi: 10.1074/jbc.M109.096255. Epub 2010 May 7.

18.

Structure predictions and interaction studies indicate homology of separase N-terminal regulatory domains and Drosophila THR.

Jäger H, Herzig B, Herzig A, Sticht H, Lehner CF, Heidmann S.

Cell Cycle. 2004 Feb;3(2):182-8.

PMID:
14712087
19.

Domain structure of separase and its binding to securin as determined by EM.

Viadiu H, Stemmann O, Kirschner MW, Walz T.

Nat Struct Mol Biol. 2005 Jun;12(6):552-3. Epub 2005 May 8.

PMID:
15880121
20.

The dual mechanism of separase regulation by securin.

Hornig NC, Knowles PP, McDonald NQ, Uhlmann F.

Curr Biol. 2002 Jun 25;12(12):973-82.

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