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Items: 1 to 20 of 100

1.

Radiologic Responses in Cynomolgus Macaques for Assessing Tuberculosis Chemotherapy Regimens.

Lin PL, Coleman T, Carney JP, Lopresti BJ, Tomko J, Fillmore D, Dartois V, Scanga C, Frye LJ, Janssen C, Klein E, Barry CE 3rd, Flynn JL.

Antimicrob Agents Chemother. 2013 Sep;57(9):4237-4244. doi: 10.1128/AAC.00277-13. Epub 2013 Jun 24.

2.

Infection dynamics and response to chemotherapy in a rabbit model of tuberculosis using [¹⁸F]2-fluoro-deoxy-D-glucose positron emission tomography and computed tomography.

Via LE, Schimel D, Weiner DM, Dartois V, Dayao E, Cai Y, Yoon YS, Dreher MR, Kastenmayer RJ, Laymon CM, Carny JE, Flynn JL, Herscovitch P, Barry CE 3rd.

Antimicrob Agents Chemother. 2012 Aug;56(8):4391-402. doi: 10.1128/AAC.00531-12. Epub 2012 Jun 11.

3.

Early Changes by (18)Fluorodeoxyglucose positron emission tomography coregistered with computed tomography predict outcome after Mycobacterium tuberculosis infection in cynomolgus macaques.

Coleman MT, Maiello P, Tomko J, Frye LJ, Fillmore D, Janssen C, Klein E, Lin PL.

Infect Immun. 2014 Jun;82(6):2400-4. doi: 10.1128/IAI.01599-13. Epub 2014 Mar 24.

4.

PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis.

Coleman MT, Chen RY, Lee M, Lin PL, Dodd LE, Maiello P, Via LE, Kim Y, Marriner G, Dartois V, Scanga C, Janssen C, Wang J, Klein E, Cho SN, Barry CE 3rd, Flynn JL.

Sci Transl Med. 2014 Dec 3;6(265):265ra167. doi: 10.1126/scitranslmed.3009500.

5.

Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin α4β1-Expressing Immune Cells.

Mattila JT, Beaino W, Maiello P, Coleman MT, White AG, Scanga CA, Flynn JL, Anderson CJ.

J Immunol. 2017 Jul 15;199(2):806-815. doi: 10.4049/jimmunol.1700231. Epub 2017 Jun 7.

PMID:
28592427
6.

[18F]-Fluorodeoxyglucose Uptake in Lymphoid Tissue Serves as a Predictor of Disease Outcome in the Nonhuman Primate Model of Monkeypox Virus Infection.

Dyall J, Johnson RF, Chefer S, Leyson C, Thomasson D, Seidel J, Ragland DR, Byrum R, Jett C, Cann JA, St Claire M, Jagoda E, Reba RC, Hammoud D, Blaney JE, Jahrling PB.

J Virol. 2017 Oct 13;91(21). pii: e00897-17. doi: 10.1128/JVI.00897-17. Print 2017 Nov 1.

7.

Noninvasive pulmonary [18F]-2-fluoro-deoxy-D-glucose positron emission tomography correlates with bactericidal activity of tuberculosis drug treatment.

Davis SL, Nuermberger EL, Um PK, Vidal C, Jedynak B, Pomper MG, Bishai WR, Jain SK.

Antimicrob Agents Chemother. 2009 Nov;53(11):4879-84. doi: 10.1128/AAC.00789-09. Epub 2009 Sep 8.

8.

[Development of antituberculous drugs: current status and future prospects].

Tomioka H, Namba K.

Kekkaku. 2006 Dec;81(12):753-74. Review. Japanese.

PMID:
17240921
9.
10.

Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques.

Phuah J, Wong EA, Gideon HP, Maiello P, Coleman MT, Hendricks MR, Ruden R, Cirrincione LR, Chan J, Lin PL, Flynn JL.

Infect Immun. 2016 Apr 22;84(5):1301-1311. doi: 10.1128/IAI.00083-16. Print 2016 May.

11.

Rhesus Macaques Are More Susceptible to Progressive Tuberculosis than Cynomolgus Macaques: a Quantitative Comparison.

Maiello P, DiFazio RM, Cadena AM, Rodgers MA, Lin PL, Scanga CA, Flynn JL.

Infect Immun. 2018 Jan 22;86(2). pii: e00505-17. doi: 10.1128/IAI.00505-17. Print 2018 Feb.

PMID:
28947646
12.

Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization.

Gideon HP, Phuah J, Myers AJ, Bryson BD, Rodgers MA, Coleman MT, Maiello P, Rutledge T, Marino S, Fortune SM, Kirschner DE, Lin PL, Flynn JL.

PLoS Pathog. 2015 Jan 22;11(1):e1004603. doi: 10.1371/journal.ppat.1004603. eCollection 2015 Jan.

13.

Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis.

Martin CJ, Cadena AM, Leung VW, Lin PL, Maiello P, Hicks N, Chase MR, Flynn JL, Fortune SM.

MBio. 2017 May 9;8(3). pii: e00312-17. doi: 10.1128/mBio.00312-17.

14.

PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis.

Lin PL, Maiello P, Gideon HP, Coleman MT, Cadena AM, Rodgers MA, Gregg R, O'Malley M, Tomko J, Fillmore D, Frye LJ, Rutledge T, DiFazio RM, Janssen C, Klein E, Andersen PL, Fortune SM, Flynn JL.

PLoS Pathog. 2016 Jul 5;12(7):e1005739. doi: 10.1371/journal.ppat.1005739. eCollection 2016 Jul.

15.

Differential virulence and disease progression following Mycobacterium tuberculosis complex infection of the common marmoset (Callithrix jacchus).

Via LE, Weiner DM, Schimel D, Lin PL, Dayao E, Tankersley SL, Cai Y, Coleman MT, Tomko J, Paripati P, Orandle M, Kastenmayer RJ, Tartakovsky M, Rosenthal A, Portevin D, Eum SY, Lahouar S, Gagneux S, Young DB, Flynn JL, Barry CE 3rd.

Infect Immun. 2013 Aug;81(8):2909-19. doi: 10.1128/IAI.00632-13. Epub 2013 May 28.

16.

(18)F-FDG positron-emission tomography/computed tomography findings of radiographic lesions suggesting old healed tuberculosis.

Jeong YJ, Paeng JC, Nam HY, Lee JS, Lee SM, Yoo CG, Kim YW, Han SK, Yim JJ.

J Korean Med Sci. 2014 Mar;29(3):386-91. doi: 10.3346/jkms.2014.29.3.386. Epub 2014 Feb 27.

17.

Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing.

Lin PL, Ford CB, Coleman MT, Myers AJ, Gawande R, Ioerger T, Sacchettini J, Fortune SM, Flynn JL.

Nat Med. 2014 Jan;20(1):75-9. doi: 10.1038/nm.3412. Epub 2013 Dec 15.

18.
19.

Advances in imaging of tuberculosis: the role of ¹⁸F-FDG PET and PET/CT.

Vorster M, Sathekge MM, Bomanji J.

Curr Opin Pulm Med. 2014 May;20(3):287-93. doi: 10.1097/MCP.0000000000000043. Review.

PMID:
24614238
20.

Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques.

Lin PL, Dartois V, Johnston PJ, Janssen C, Via L, Goodwin MB, Klein E, Barry CE 3rd, Flynn JL.

Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14188-93. doi: 10.1073/pnas.1121497109. Epub 2012 Jul 23.

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