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Items: 1 to 20 of 121

1.

Characteristics of major Escherichia coli reductases involved in aerobic nitro and azo reduction.

Mercier C, Chalansonnet V, Orenga S, Gilbert C.

J Appl Microbiol. 2013 Oct;115(4):1012-22. doi: 10.1111/jam.12294. Epub 2013 Jul 19.

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Oxygen-insensitive nitroreductases: analysis of the roles of nfsA and nfsB in development of resistance to 5-nitrofuran derivatives in Escherichia coli.

Whiteway J, Koziarz P, Veall J, Sandhu N, Kumar P, Hoecher B, Lambert IB.

J Bacteriol. 1998 Nov;180(21):5529-39.

9.

An in vitro deletion in ribE encoding lumazine synthase contributes to nitrofurantoin resistance in Escherichia coli.

Vervoort J, Xavier BB, Stewardson A, Coenen S, Godycki-Cwirko M, Adriaenssens N, Kowalczyk A, Lammens C, Harbarth S, Goossens H, Malhotra-Kumar S.

Antimicrob Agents Chemother. 2014 Dec;58(12):7225-33. doi: 10.1128/AAC.03952-14. Epub 2014 Sep 22.

10.

Discovery and evaluation of Escherichia coli nitroreductases that activate the anti-cancer prodrug CB1954.

Prosser GA, Copp JN, Syddall SP, Williams EM, Smaill JB, Wilson WR, Patterson AV, Ackerley DF.

Biochem Pharmacol. 2010 Mar 1;79(5):678-87. doi: 10.1016/j.bcp.2009.10.008. Epub 2009 Oct 21.

PMID:
19852945
11.
12.

Residue Phe42 is critical for the catalytic activity of Escherichia coli major nitroreductase NfsA.

Yang J, Zhan J, Bai J, Liu P, Xue Y, Yang Q.

Biotechnol Lett. 2013 Oct;35(10):1693-700. doi: 10.1007/s10529-013-1262-y. Epub 2013 Jun 26.

PMID:
23801116
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14.
15.

Three-dimensional structure of AzoR from Escherichia coli. An oxidereductase conserved in microorganisms.

Ito K, Nakanishi M, Lee WC, Sasaki H, Zenno S, Saigo K, Kitade Y, Tanokura M.

J Biol Chem. 2006 Jul 21;281(29):20567-76. Epub 2006 May 9.

16.

Pseudomonas aeruginosa NfsB and nitro-CBI-DEI--a promising enzyme/prodrug combination for gene directed enzyme prodrug therapy.

Green LK, Syddall SP, Carlin KM, Bell GD, Guise CP, Mowday AM, Hay MP, Smaill JB, Patterson AV, Ackerley DF.

Mol Cancer. 2013 Jun 10;12:58. doi: 10.1186/1476-4598-12-58.

17.

E. coli NfsA: an alternative nitroreductase for prodrug activation gene therapy in combination with CB1954.

Vass SO, Jarrom D, Wilson WR, Hyde EI, Searle PF.

Br J Cancer. 2009 Jun 16;100(12):1903-11. doi: 10.1038/sj.bjc.6605094. Epub 2009 May 19.

18.
19.

Steady-state and stopped-flow kinetic studies of three Escherichia coli NfsB mutants with enhanced activity for the prodrug CB1954.

Jarrom D, Jaberipour M, Guise CP, Daff S, White SA, Searle PF, Hyde EI.

Biochemistry. 2009 Aug 18;48(32):7665-72. doi: 10.1021/bi900674m.

PMID:
19580253
20.

Oxygen-insensitive nitroreductases of Escherichia coli do not reduce 3-nitrotyrosine.

Lightfoot RT, Shuman D, Ischiropoulos H.

Free Radic Biol Med. 2000 Apr 1;28(7):1132-6.

PMID:
10832075

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