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A synergistic vascular effect of airborne particulate matter and nickel in a mouse model.

Ying Z, Xu X, Chen M, Liu D, Zhong M, Chen LC, Sun Q, Rajagopalan S.

Toxicol Sci. 2013 Sep;135(1):72-80. doi: 10.1093/toxsci/kft136.


Endothelial dysfunction in the pulmonary artery induced by concentrated fine particulate matter exposure is associated with local but not systemic inflammation.

Davel AP, Lemos M, Pastro LM, Pedro SC, de André PA, Hebeda C, Farsky SH, Saldiva PH, Rossoni LV.

Toxicology. 2012 May 16;295(1-3):39-46. doi: 10.1016/j.tox.2012.02.004.


Effect of co-exposure to nickel and particulate matter on insulin resistance and mitochondrial dysfunction in a mouse model.

Xu X, Rao X, Wang TY, Jiang SY, Ying Z, Liu C, Wang A, Zhong M, Deiuliis JA, Maiseyeu A, Rajagopalan S, Lippmann M, Chen LC, Sun Q.

Part Fibre Toxicol. 2012 Nov 5;9:40. doi: 10.1186/1743-8977-9-40.


Exposure to ambient air fine particulate matter prevents VEGF-induced mobilization of endothelial progenitor cells from the bone marrow.

Haberzettl P, Lee J, Duggineni D, McCracken J, Bolanowski D, O'Toole TE, Bhatnagar A, Conklin DJ.

Environ Health Perspect. 2012 Jun;120(6):848-56. doi: 10.1289/ehp.1104206.


Exposure to Fine Particulate Air Pollution Causes Vascular Insulin Resistance by Inducing Pulmonary Oxidative Stress.

Haberzettl P, O'Toole TE, Bhatnagar A, Conklin DJ.

Environ Health Perspect. 2016 Dec;124(12):1830-1839.


High density lipoprotein from patients with valvular heart disease uncouples endothelial nitric oxide synthase.

Chang FJ, Yuan HY, Hu XX, Ou ZJ, Fu L, Lin ZB, Wang ZP, Wang SM, Zhou L, Xu YQ, Wang CP, Xu Z, Zhang X, Zhang CX, Ou JS.

J Mol Cell Cardiol. 2014 Sep;74:209-19. doi: 10.1016/j.yjmcc.2014.05.015. Erratum in: J Mol Cell Cardiol. 2015 Apr;81:176.


Isoproterenol induces vascular oxidative stress and endothelial dysfunction via a Giα-coupled β2-adrenoceptor signaling pathway.

Davel AP, Brum PC, Rossoni LV.

PLoS One. 2014 Mar 12;9(3):e91877. doi: 10.1371/journal.pone.0091877.


Propofol protects against high glucose-induced endothelial dysfunction in human umbilical vein endothelial cells.

Zhu M, Chen J, Tan Z, Wang J.

Anesth Analg. 2012 Feb;114(2):303-9. doi: 10.1213/ANE.0b013e31823f0c42.


Metal rich particulate matter impairs acetylcholine-mediated vasorelaxation of microvessels in mice.

Cuevas AK, Niu J, Zhong M, Liberda EN, Ghio A, Qu Q, Chen LC.

Part Fibre Toxicol. 2015 Jun 4;12:14. doi: 10.1186/s12989-014-0077-x.


Inflammatory monocytes determine endothelial nitric-oxide synthase uncoupling and nitro-oxidative stress induced by angiotensin II.

Kossmann S, Hu H, Steven S, Schönfelder T, Fraccarollo D, Mikhed Y, Brähler M, Knorr M, Brandt M, Karbach SH, Becker C, Oelze M, Bauersachs J, Widder J, Münzel T, Daiber A, Wenzel P.

J Biol Chem. 2014 Oct 3;289(40):27540-50. doi: 10.1074/jbc.M114.604231.


Amyloid β peptide-induced inhibition of endothelial nitric oxide production involves oxidative stress-mediated constitutive eNOS/HSP90 interaction and disruption of agonist-mediated Akt activation.

Lamoke F, Mazzone V, Persichini T, Maraschi A, Harris MB, Venema RC, Colasanti M, Gliozzi M, Muscoli C, Bartoli M, Mollace V.

J Neuroinflammation. 2015 May 3;12:84. doi: 10.1186/s12974-015-0304-x.


Syringaresinol causes vasorelaxation by elevating nitric oxide production through the phosphorylation and dimerization of endothelial nitric oxide synthase.

Chung BH, Kim S, Kim JD, Lee JJ, Baek YY, Jeoung D, Lee H, Choe J, Ha KS, Won MH, Kwon YG, Kim YM.

Exp Mol Med. 2012 Mar 31;44(3):191-201. doi: 10.3858/emm.2012.44.3.014.


Adiponectin improves endothelial function in hyperlipidemic rats by reducing oxidative/nitrative stress and differential regulation of eNOS/iNOS activity.

Li R, Wang WQ, Zhang H, Yang X, Fan Q, Christopher TA, Lopez BL, Tao L, Goldstein BJ, Gao F, Ma XL.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1703-8.


A Novel Arginase Inhibitor Derived from Scutellavia indica Restored Endothelial Function in ApoE-Null Mice Fed a High-Cholesterol Diet.

Hwang HM, Lee JH, Min BS, Jeon BH, Hoe KL, Kim YM, Ryoo S.

J Pharmacol Exp Ther. 2015 Oct;355(1):57-65. doi: 10.1124/jpet.115.224592.


Endothelial nitric oxide synthase uncoupling and perivascular adipose oxidative stress and inflammation contribute to vascular dysfunction in a rodent model of metabolic syndrome.

Marchesi C, Ebrahimian T, Angulo O, Paradis P, Schiffrin EL.

Hypertension. 2009 Dec;54(6):1384-92. doi: 10.1161/HYPERTENSIONAHA.109.138305.


Exposure to inhaled nickel nanoparticles causes a reduction in number and function of bone marrow endothelial progenitor cells.

Liberda EN, Cuevas AK, Gillespie PA, Grunig G, Qu Q, Chen LC.

Inhal Toxicol. 2010 Dec;22 Suppl 2:95-9. doi: 10.3109/08958378.2010.515269. Erratum in: Inhal Toxicol. 2013 Mar;25(4):233.


Long-term atorvastatin improves age-related endothelial dysfunction by ameliorating oxidative stress and normalizing eNOS/iNOS imbalance in rat aorta.

Gong X, Ma Y, Ruan Y, Fu G, Wu S.

Exp Gerontol. 2014 Apr;52:9-17. doi: 10.1016/j.exger.2014.01.015.


Effects of concentrated ambient particles on normal and hypersecretory airways in rats.

Harkema JR, Keeler G, Wagner J, Morishita M, Timm E, Hotchkiss J, Marsik F, Dvonch T, Kaminski N, Barr E.

Res Rep Health Eff Inst. 2004 Aug;(120):1-68; discussion 69-79.


Dietary Supplementation with Olive Oil or Fish Oil and Vascular Effects of Concentrated Ambient Particulate Matter Exposure in Human Volunteers.

Tong H, Rappold AG, Caughey M, Hinderliter AL, Bassett M, Montilla T, Case MW, Berntsen J, Bromberg PA, Cascio WE, Diaz-Sanchez D, Devlin RB, Samet JM.

Environ Health Perspect. 2015 Nov;123(11):1173-9. doi: 10.1289/ehp.1408988.


Vascular endothelial growth factor inhibition by dRK6 causes endothelial apoptosis, fibrosis, and inflammation in the heart via the Akt/eNOS axis in db/db mice.

Park CW, Kim HW, Lim JH, Yoo KD, Chung S, Shin SJ, Chung HW, Lee SJ, Chae CB, Kim YS, Chang YS.

Diabetes. 2009 Nov;58(11):2666-76. doi: 10.2337/db09-0136.

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