Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 112


The relative contributions of CYP3A4 and CYP3A5 to the metabolism of vinorelbine.

Topletz AR, Dennison JB, Barbuch RJ, Hadden CE, Hall SD, Renbarger JL.

Drug Metab Dispos. 2013 Sep;41(9):1651-61. doi: 10.1124/dmd.113.051094. Epub 2013 Jun 18.


Effect of CYP3A5 expression on vincristine metabolism with human liver microsomes.

Dennison JB, Jones DR, Renbarger JL, Hall SD.

J Pharmacol Exp Ther. 2007 May;321(2):553-63. Epub 2007 Feb 1.


Metabolism of quetiapine by CYP3A4 and CYP3A5 in presence or absence of cytochrome B5.

Bakken GV, Rudberg I, Christensen H, Molden E, Refsum H, Hermann M.

Drug Metab Dispos. 2009 Feb;37(2):254-8. doi: 10.1124/dmd.108.023291. Epub 2008 Nov 20.


In Vitro Kinetic Characterization of Axitinib Metabolism.

Zientek MA, Goosen TC, Tseng E, Lin J, Bauman JN, Walker GS, Kang P, Jiang Y, Freiwald S, Neul D, Smith BJ.

Drug Metab Dispos. 2016 Jan;44(1):102-14. doi: 10.1124/dmd.115.065615. Epub 2015 Oct 28.


CYP3A4 is mainly responsibile for the metabolism of a new vinca alkaloid, vinorelbine, in human liver microsomes.

Kajita J, Kuwabara T, Kobayashi H, Kobayashi S.

Drug Metab Dispos. 2000 Sep;28(9):1121-7.


Relative contributions of cytochrome CYP3A4 versus CYP3A5 for CYP3A-cleared drugs assessed in vitro using a CYP3A4-selective inactivator (CYP3cide).

Tseng E, Walsky RL, Luzietti RA Jr, Harris JJ, Kosa RE, Goosen TC, Zientek MA, Obach RS.

Drug Metab Dispos. 2014 Jul;42(7):1163-73. doi: 10.1124/dmd.114.057000. Epub 2014 Apr 15.


The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4.

Gallagher EP, Kunze KL, Stapleton PL, Eaton DL.

Toxicol Appl Pharmacol. 1996 Dec;141(2):595-606.


Assessment of the impact of CYP3A polymorphisms on the formation of ╬▒-hydroxytamoxifen and N-desmethyltamoxifen in human liver microsomes.

Mugundu GM, Sallans L, Guo Y, Shaughnessy EA, Desai PB.

Drug Metab Dispos. 2012 Feb;40(2):389-96. doi: 10.1124/dmd.111.039388. Epub 2011 Nov 17.


Pharmacogenetic determinants of human liver microsomal alfentanil metabolism and the role of cytochrome P450 3A5.

Klees TM, Sheffels P, Thummel KE, Kharasch ED.

Anesthesiology. 2005 Mar;102(3):550-6.


Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7.

Williams JA, Ring BJ, Cantrell VE, Jones DR, Eckstein J, Ruterbories K, Hamman MA, Hall SD, Wrighton SA.

Drug Metab Dispos. 2002 Aug;30(8):883-91.


In vitro characterization of 4'-(p-toluenesulfonylamide)-4-hydroxychalcone using human liver microsomes and recombinant cytochrome P450s.

Lee B, Wu Z, Lee T, Tan XF, Park KH, Liu KH.

Xenobiotica. 2016;46(4):350-6. doi: 10.3109/00498254.2015.1081306. Epub 2015 Sep 2.


Evidence of significant contribution from CYP3A5 to hepatic drug metabolism.

Huang W, Lin YS, McConn DJ 2nd, Calamia JC, Totah RA, Isoherranen N, Glodowski M, Thummel KE.

Drug Metab Dispos. 2004 Dec;32(12):1434-45. Epub 2004 Sep 21.


Contribution of CYP3A5 to the in vitro hepatic clearance of tacrolimus.

Kamdem LK, Streit F, Zanger UM, Brockm├Âller J, Oellerich M, Armstrong VW, Wojnowski L.

Clin Chem. 2005 Aug;51(8):1374-81. Epub 2005 Jun 10.


Cytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of Lapatinib.

Towles JK, Clark RN, Wahlin MD, Uttamsingh V, Rettie AE, Jackson KD.

Drug Metab Dispos. 2016 Oct;44(10):1584-97. doi: 10.1124/dmd.116.070839. Epub 2016 Jul 22.


Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4.

Casabar RC, Wallace AD, Hodgson E, Rose RL.

Drug Metab Dispos. 2006 Oct;34(10):1779-85. Epub 2006 Jul 19.


Gomisin A is a Novel Isoform-Specific Probe for the Selective Sensing of Human Cytochrome P450 3A4 in Liver Microsomes and Living Cells.

Wu JJ, Ge GB, He YQ, Wang P, Dai ZR, Ning J, Hu LH, Yang L.

AAPS J. 2016 Jan;18(1):134-45. doi: 10.1208/s12248-015-9827-4. Epub 2015 Sep 11.


Selective metabolism of vincristine in vitro by CYP3A5.

Dennison JB, Kulanthaivel P, Barbuch RJ, Renbarger JL, Ehlhardt WJ, Hall SD.

Drug Metab Dispos. 2006 Aug;34(8):1317-27. Epub 2006 May 5.

Supplemental Content

Support Center