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Items: 1 to 20 of 113

1.

Deletion of phd2 in myeloid lineage attenuates hypertensive cardiovascular remodeling.

Ikeda J, Ichiki T, Matsuura H, Inoue E, Kishimoto J, Watanabe A, Sankoda C, Kitamoto S, Tokunou T, Takeda K, Fong GH, Sunagawa K.

J Am Heart Assoc. 2013 Jun 18;2(3):e000178. doi: 10.1161/JAHA.113.000178.

2.

Silencing of HIF prolyl-hydroxylase 2 gene in the renal medulla attenuates salt-sensitive hypertension in Dahl S rats.

Zhu Q, Hu J, Han WQ, Zhang F, Li PL, Wang Z, Li N.

Am J Hypertens. 2014 Jan;27(1):107-13. doi: 10.1093/ajh/hpt207. Epub 2013 Nov 4.

3.

Inhibition of prolyl hydroxylase domain-containing protein on hypertension/renal injury induced by high salt diet and nitric oxide withdrawal.

Dallatu MK, Choi M, Oyekan AO.

J Hypertens. 2013 Oct;31(10):2043-9. doi: 10.1097/HJH.0b013e32836356a0.

PMID:
23811999
4.

Conditional knockout of prolyl hydroxylase domain protein 2 attenuates high fat-diet-induced cardiac dysfunction in mice.

Zeng H, Chen JX.

PLoS One. 2014 Dec 29;9(12):e115974. doi: 10.1371/journal.pone.0115974. eCollection 2014.

5.
6.

Conditional Deletion of Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Gene Reveals Its Essential Role in Chondrocyte Function and Endochondral Bone Formation.

Cheng S, Xing W, Pourteymoor S, Schulte J, Mohan S.

Endocrinology. 2016 Jan;157(1):127-40. doi: 10.1210/en.2015-1473. Epub 2015 Nov 12.

8.

Smooth muscle cell-specific Hif-1α deficiency suppresses angiotensin II-induced vascular remodelling in mice.

Imanishi M, Tomita S, Ishizawa K, Kihira Y, Ueno M, Izawa-Ishizawa Y, Ikeda Y, Yamano N, Tsuchiya K, Tamaki T.

Cardiovasc Res. 2014 Jun 1;102(3):460-8. doi: 10.1093/cvr/cvu061. Epub 2014 Mar 12.

PMID:
24623277
9.

Deletion of hypoxia-inducible factor-1α in myeloid lineage exaggerates angiotensin II-induced formation of abdominal aortic aneurysm.

Takahara Y, Tokunou T, Kojima H, Hirooka Y, Ichiki T.

Clin Sci (Lond). 2017 Apr 1;131(7):609-620. doi: 10.1042/CS20160865. Epub 2017 Feb 14.

PMID:
28196857
10.

Pharmacological inhibition and genetic deficiency of plasminogen activator inhibitor-1 attenuates angiotensin II/salt-induced aortic remodeling.

Weisberg AD, Albornoz F, Griffin JP, Crandall DL, Elokdah H, Fogo AB, Vaughan DE, Brown NJ.

Arterioscler Thromb Vasc Biol. 2005 Feb;25(2):365-71. Epub 2004 Dec 2.

11.

Asiatic acid alleviates cardiovascular remodelling in rats with L-NAME-induced hypertension.

Bunbupha S, Prachaney P, Kukongviriyapan U, Kukongviriyapan V, Welbat JU, Pakdeechote P.

Clin Exp Pharmacol Physiol. 2015 Nov;42(11):1189-97. doi: 10.1111/1440-1681.12472.

PMID:
26234646
12.

Hypoxia-Inducible Factor Prolyl 4-Hydroxylase-2 Inhibition Protects Against Development of Atherosclerosis.

Rahtu-Korpela L, Määttä J, Dimova EY, Hörkkö S, Gylling H, Walkinshaw G, Hakkola J, Kivirikko KI, Myllyharju J, Serpi R, Koivunen P.

Arterioscler Thromb Vasc Biol. 2016 Apr;36(4):608-17. doi: 10.1161/ATVBAHA.115.307136. Epub 2016 Feb 4.

13.

Targeting the calpain/calpastatin system as a new strategy to prevent cardiovascular remodeling in angiotensin II-induced hypertension.

Letavernier E, Perez J, Bellocq A, Mesnard L, de Castro Keller A, Haymann JP, Baud L.

Circ Res. 2008 Mar 28;102(6):720-8. doi: 10.1161/CIRCRESAHA.107.160077. Epub 2008 Feb 7.

14.

Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway.

Hodson EJ, Nicholls LG, Turner PJ, Llyr R, Fielding JW, Douglas G, Ratnayaka I, Robbins PA, Pugh CW, Buckler KJ, Ratcliffe PJ, Bishop T.

J Physiol. 2016 Mar 1;594(5):1179-95. doi: 10.1113/JP271050. Epub 2015 Oct 6.

15.

Neuron-specific prolyl-4-hydroxylase domain 2 knockout reduces brain injury after transient cerebral ischemia.

Kunze R, Zhou W, Veltkamp R, Wielockx B, Breier G, Marti HH.

Stroke. 2012 Oct;43(10):2748-56. Epub 2012 Aug 28.

16.

Hypoxia-inducible factor prolyl-hydroxylase-2 mediates transforming growth factor beta 1-induced epithelial-mesenchymal transition in renal tubular cells.

Han WQ, Zhu Q, Hu J, Li PL, Zhang F, Li N.

Biochim Biophys Acta. 2013 Jun;1833(6):1454-62. doi: 10.1016/j.bbamcr.2013.02.029. Epub 2013 Mar 1.

17.

Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury.

Natarajan R, Salloum FN, Fisher BJ, Kukreja RC, Fowler AA 3rd.

Circ Res. 2006 Jan 6;98(1):133-40. Epub 2005 Nov 23.

18.

Hypoxia-inducible factor prolyl-hydroxylase 2 senses high-salt intake to increase hypoxia inducible factor 1alpha levels in the renal medulla.

Wang Z, Zhu Q, Xia M, Li PL, Hinton SJ, Li N.

Hypertension. 2010 May;55(5):1129-36. doi: 10.1161/HYPERTENSIONAHA.109.145896. Epub 2010 Mar 22.

19.

Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.

Marxsen JH, Stengel P, Doege K, Heikkinen P, Jokilehto T, Wagner T, Jelkmann W, Jaakkola P, Metzen E.

Biochem J. 2004 Aug 1;381(Pt 3):761-7.

20.

Enhancement of angiogenesis through stabilization of hypoxia-inducible factor-1 by silencing prolyl hydroxylase domain-2 gene.

Wu S, Nishiyama N, Kano MR, Morishita Y, Miyazono K, Itaka K, Chung UI, Kataoka K.

Mol Ther. 2008 Jul;16(7):1227-34. doi: 10.1038/mt.2008.90. Epub 2008 May 20.

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