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Items: 1 to 20 of 73

1.

Epitope mapping of M36, a human antibody domain with potent and broad HIV-1 inhibitory activity.

Wan C, Sun J, Chen W, Yuan X, Chong H, Prabakaran P, Dimitrov DS, He Y.

PLoS One. 2013 Jun 11;8(6):e66638. doi: 10.1371/journal.pone.0066638. Print 2013.

2.

Bifunctional fusion proteins of the human engineered antibody domain m36 with human soluble CD4 are potent inhibitors of diverse HIV-1 isolates.

Chen W, Xiao X, Wang Y, Zhu Z, Dimitrov DS.

Antiviral Res. 2010 Oct;88(1):107-15. doi: 10.1016/j.antiviral.2010.08.004. Epub 2010 Aug 13.

3.

Strain specificity and binding affinity requirements of neutralizing monoclonal antibodies to the C4 domain of gp120 from human immunodeficiency virus type 1.

Nakamura GR, Byrn R, Wilkes DM, Fox JA, Hobbs MR, Hastings R, Wessling HC, Norcross MA, Fendly BM, Berman PW.

J Virol. 1993 Oct;67(10):6179-91.

4.

Germlining of the HIV-1 broadly neutralizing antibody domain m36.

Chen W, Li W, Ying T, Wang Y, Feng Y, Dimitrov DS.

Antiviral Res. 2015 Apr;116:62-6. doi: 10.1016/j.antiviral.2015.02.001. Epub 2015 Feb 9.

5.

Structural elements of primary CCR5-using HIV-1 gp120 proteins influencing sensitivity and resistance to the broadly neutralizing monoclonal antibody b12.

Sterjovski J, Churchill MJ, Ellett A, Wesselingh SL, Ramsland PA, Gorry PR.

Virology. 2012 Oct 25;432(2):394-404. doi: 10.1016/j.virol.2012.06.024. Epub 2012 Jul 19.

6.

Human domain antibodies to conserved sterically restricted regions on gp120 as exceptionally potent cross-reactive HIV-1 neutralizers.

Chen W, Zhu Z, Feng Y, Dimitrov DS.

Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17121-6. doi: 10.1073/pnas.0805297105. Epub 2008 Oct 28.

7.
8.

epitopes immediately below the base of the V3 loop of gp120 as targets for the initial autologous neutralizing antibody response in two HIV-1 subtype B-infected individuals.

Tang H, Robinson JE, Gnanakaran S, Li M, Rosenberg ES, Perez LG, Haynes BF, Liao HX, Labranche CC, Korber BT, Montefiori DC.

J Virol. 2011 Sep;85(18):9286-99. doi: 10.1128/JVI.02286-10. Epub 2011 Jul 6.

10.

Neutralizing recombinant human antibodies to a conformational V2- and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure.

Ditzel HJ, Binley JM, Moore JP, Sodroski J, Sullivan N, Sawyer LS, Hendry RM, Yang WP, Barbas CF 3rd, Burton DR.

J Immunol. 1995 Jan 15;154(2):893-906.

PMID:
7529290
11.

Design and synthesis of a highly immunogenic, discontinuous epitope of HIV-1 gp120 which binds to CD4+ve transfected cells.

Cotton GJ, Howie SE, Heslop I, Ross JA, Harrison DJ, Ramage R.

Mol Immunol. 1996 Feb;33(2):171-8.

PMID:
8649438
12.
13.

Epitope mapping and characterization of a novel CD4-induced human monoclonal antibody capable of neutralizing primary HIV-1 strains.

Xiang SH, Wang L, Abreu M, Huang CC, Kwong PD, Rosenberg E, Robinson JE, Sodroski J.

Virology. 2003 Oct 10;315(1):124-34.

14.

HIV-1 V3 loop crown epitope-focused mimotope selection by patient serum from random phage display libraries: implications for the epitope structural features.

Gazarian KG, Palacios-Rodríguez Y, Gazarian TG, Huerta L.

Mol Immunol. 2013 Jun;54(2):148-56. doi: 10.1016/j.molimm.2012.11.016. Epub 2012 Dec 25.

PMID:
23270686
16.

Phage-displayed mimotopes recognizing a biologically active anti-HIV-1 gp120 murine monoclonal antibody.

Gómez-Román VR, Cao C, Bai Y, Santamaría H, Acero G, Manoutcharian K, Weiner DB, Ugen KE, Gevorkian G.

J Acquir Immune Defic Syndr. 2002 Oct 1;31(2):147-53.

PMID:
12394792
18.

Crystal structure of the broadly cross-reactive HIV-1-neutralizing Fab X5 and fine mapping of its epitope.

Darbha R, Phogat S, Labrijn AF, Shu Y, Gu Y, Andrykovitch M, Zhang MY, Pantophlet R, Martin L, Vita C, Burton DR, Dimitrov DS, Ji X.

Biochemistry. 2004 Feb 17;43(6):1410-7.

PMID:
14769016
20.

Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes.

Moulard M, Phogat SK, Shu Y, Labrijn AF, Xiao X, Binley JM, Zhang MY, Sidorov IA, Broder CC, Robinson J, Parren PW, Burton DR, Dimitrov DS.

Proc Natl Acad Sci U S A. 2002 May 14;99(10):6913-8. Epub 2002 May 7.

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