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Items: 1 to 20 of 130

1.

A transgenic TCR directs the development of IL-4+ and PLZF+ innate CD4 T cells.

Zhu L, Qiao Y, Choi ES, Das J, Sant'angelo DB, Chang CH.

J Immunol. 2013 Jul 15;191(2):737-44. doi: 10.4049/jimmunol.1300862. Epub 2013 Jun 17.

2.

Promyelocytic leukemia zinc finger turns on the effector T cell program without requirement for agonist TCR signaling.

Savage AK, Constantinides MG, Bendelac A.

J Immunol. 2011 May 15;186(10):5801-6. doi: 10.4049/jimmunol.1100119. Epub 2011 Apr 8.

3.

Innate PLZF+CD4+ αβ T cells develop and expand in the absence of Itk.

Prince AL, Watkin LB, Yin CC, Selin LK, Kang J, Schwartzberg PL, Berg LJ.

J Immunol. 2014 Jul 15;193(2):673-87. doi: 10.4049/jimmunol.1302058. Epub 2014 Jun 13.

4.

Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells.

Qiao Y, Zhu L, Sofi H, Lapinski PE, Horai R, Mueller K, Stritesky GL, He X, Teh HS, Wiest DL, Kappes DJ, King PD, Hogquist KA, Schwartzberg PL, Sant'Angelo DB, Chang CH.

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16264-9. doi: 10.1073/pnas.1207528109. Epub 2012 Sep 17.

5.

Development of innate CD4+ and CD8+ T cells in Itk-deficient mice is regulated by distinct pathways.

Prince AL, Kraus Z, Carty SA, Ng C, Yin CC, Jordan MS, Schwartzberg PL, Berg LJ.

J Immunol. 2014 Jul 15;193(2):688-99. doi: 10.4049/jimmunol.1302059. Epub 2014 Jun 18.

6.

Subcellular distribution of Lck during CD4 T-cell maturation in the thymic medulla regulates the T-cell activation threshold.

Stephen TL, Wilson BS, Laufer TM.

Proc Natl Acad Sci U S A. 2012 May 8;109(19):7415-20. doi: 10.1073/pnas.1119272109. Epub 2012 Apr 23.

7.

A role for Ly108 in the induction of promyelocytic zinc finger transcription factor in developing thymocytes.

Dutta M, Kraus ZJ, Gomez-Rodriguez J, Hwang SH, Cannons JL, Cheng J, Lee SY, Wiest DL, Wakeland EK, Schwartzberg PL.

J Immunol. 2013 Mar 1;190(5):2121-8. doi: 10.4049/jimmunol.1202145. Epub 2013 Jan 25.

8.

PLZF induces the spontaneous acquisition of memory/effector functions in T cells independently of NKT cell-related signals.

Kovalovsky D, Alonzo ES, Uche OU, Eidson M, Nichols KE, Sant'Angelo DB.

J Immunol. 2010 Jun 15;184(12):6746-55. doi: 10.4049/jimmunol.1000776. Epub 2010 May 21.

9.

Jarid2 is induced by TCR signalling and controls iNKT cell maturation.

Pereira RM, Martinez GJ, Engel I, Cruz-Guilloty F, Barboza BA, Tsagaratou A, Lio CW, Berg LJ, Lee Y, Kronenberg M, Bandukwala HS, Rao A.

Nat Commun. 2014 Aug 8;5:4540. doi: 10.1038/ncomms5540.

10.

MHC class II-restricted interaction between thymocytes plays an essential role in the production of innate CD8+ T cells.

Min HS, Lee YJ, Jeon YK, Kim EJ, Kang BH, Jung KC, Chang CH, Park SH.

J Immunol. 2011 May 15;186(10):5749-57. doi: 10.4049/jimmunol.1002825. Epub 2011 Apr 8.

11.

CD4(+) T cells from MHC II-dependent thymocyte-thymocyte interaction provide efficient help for B cells.

Kim EJ, Choi B, Moon H, Lee YJ, Jeon YK, Park SH, Kim TJ, Jung KC.

Immunol Cell Biol. 2011 Nov;89(8):897-903. doi: 10.1038/icb.2011.8. Epub 2011 Mar 1.

13.

PLZF(+) Innate T Cells Support the TGF-β-Dependent Generation of Activated/Memory-Like Regulatory T Cells.

Kang BH, Park HJ, Park HJ, Lee JI, Park SH, Jung KC.

Mol Cells. 2016 Jun 30;39(6):468-76. doi: 10.14348/molcells.2016.0004. Epub 2016 Apr 20.

14.

Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength.

Izon DJ, Punt JA, Xu L, Karnell FG, Allman D, Myung PS, Boerth NJ, Pui JC, Koretzky GA, Pear WS.

Immunity. 2001 Mar;14(3):253-64.

15.

The activation threshold of CD4+ T cells is defined by TCR/peptide-MHC class II interactions in the thymic medulla.

Stephen TL, Tikhonova A, Riberdy JM, Laufer TM.

J Immunol. 2009 Nov 1;183(9):5554-62. doi: 10.4049/jimmunol.0901104.

16.

Generation of PLZF+ CD4+ T cells via MHC class II-dependent thymocyte-thymocyte interaction is a physiological process in humans.

Lee YJ, Jeon YK, Kang BH, Chung DH, Park CG, Shin HY, Jung KC, Park SH.

J Exp Med. 2010 Jan 18;207(1):237-46. doi: 10.1084/jem.20091519. Epub 2009 Dec 28.

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20.

Pak2 Controls Acquisition of NKT Cell Fate by Regulating Expression of the Transcription Factors PLZF and Egr2.

O'Hagan KL, Zhao J, Pryshchep O, Wang CR, Phee H.

J Immunol. 2015 Dec 1;195(11):5272-84. doi: 10.4049/jimmunol.1501367. Epub 2015 Oct 30.

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