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Items: 1 to 20 of 106

1.

Common dysfunctional variants in ABCG2 are a major cause of early-onset gout.

Matsuo H, Ichida K, Takada T, Nakayama A, Nakashima H, Nakamura T, Kawamura Y, Takada Y, Yamamoto K, Inoue H, Oikawa Y, Naito M, Hishida A, Wakai K, Okada C, Shimizu S, Sakiyama M, Chiba T, Ogata H, Niwa K, Hosoyamada M, Mori A, Hamajima N, Suzuki H, Kanai Y, Sakurai Y, Hosoya T, Shimizu T, Shinomiya N.

Sci Rep. 2013;3:2014. doi: 10.1038/srep02014.

2.

ABCG2/BCRP dysfunction as a major cause of gout.

Matsuo H, Takada T, Ichida K, Nakamura T, Nakayama A, Suzuki H, Hosoya T, Shinomiya N.

Nucleosides Nucleotides Nucleic Acids. 2011 Dec;30(12):1117-28. doi: 10.1080/15257770.2011.633954.

PMID:
22132966
3.

Identification of ABCG2 dysfunction as a major factor contributing to gout.

Matsuo H, Takada T, Ichida K, Nakamura T, Nakayama A, Takada Y, Okada C, Sakurai Y, Hosoya T, Kanai Y, Suzuki H, Shinomiya N.

Nucleosides Nucleotides Nucleic Acids. 2011 Dec;30(12):1098-104. doi: 10.1080/15257770.2011.627902.

PMID:
22132963
4.

Common defects of ABCG2, a high-capacity urate exporter, cause gout: a function-based genetic analysis in a Japanese population.

Matsuo H, Takada T, Ichida K, Nakamura T, Nakayama A, Ikebuchi Y, Ito K, Kusanagi Y, Chiba T, Tadokoro S, Takada Y, Oikawa Y, Inoue H, Suzuki K, Okada R, Nishiyama J, Domoto H, Watanabe S, Fujita M, Morimoto Y, Naito M, Nishio K, Hishida A, Wakai K, Asai Y, Niwa K, Kamakura K, Nonoyama S, Sakurai Y, Hosoya T, Kanai Y, Suzuki H, Hamajima N, Shinomiya N.

Sci Transl Med. 2009 Nov 4;1(5):5ra11. doi: 10.1126/scitranslmed.3000237.

5.

ABCG2 dysfunction increases the risk of renal overload hyperuricemia.

Matsuo H, Takada T, Nakayama A, Shimizu T, Sakiyama M, Shimizu S, Chiba T, Nakashima H, Nakamura T, Takada Y, Sakurai Y, Hosoya T, Shinomiya N, Ichida K.

Nucleosides Nucleotides Nucleic Acids. 2014;33(4-6):266-74. doi: 10.1080/15257770.2013.866679.

PMID:
24940678
6.

Functional polymorphisms of the ABCG2 gene are associated with gout disease in the Chinese Han male population.

Zhou D, Liu Y, Zhang X, Gu X, Wang H, Luo X, Zhang J, Zou H, Guan M.

Int J Mol Sci. 2014 May 22;15(5):9149-59. doi: 10.3390/ijms15059149.

7.

The rs2231142 variant of the ABCG2 gene is associated with uric acid levels and gout among Japanese people.

Yamagishi K, Tanigawa T, Kitamura A, Köttgen A, Folsom AR, Iso H; CIRCS Investigators.

Rheumatology (Oxford). 2010 Aug;49(8):1461-5. doi: 10.1093/rheumatology/keq096. Epub 2010 Apr 25.

PMID:
20421215
8.

[Recent progress and prospects for research on urate efflux transporter ABCG2].

Ichida K.

Nihon Rinsho. 2014 Apr;72(4):757-65. Review. Japanese.

PMID:
24796111
9.

Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors.

Nakayama A, Matsuo H, Nakaoka H, Nakamura T, Nakashima H, Takada Y, Oikawa Y, Takada T, Sakiyama M, Shimizu S, Kawamura Y, Chiba T, Abe J, Wakai K, Kawai S, Okada R, Tamura T, Shichijo Y, Akashi A, Suzuki H, Hosoya T, Sakurai Y, Ichida K, Shinomiya N.

Sci Rep. 2014 Jun 9;4:5227. doi: 10.1038/srep05227.

10.

Ethnic differences in ATP-binding cassette transporter, sub-family G, member 2 (ABCG2/BCRP): genotype combinations and estimated functions.

Sakiyama M, Matsuo H, Takada Y, Nakamura T, Nakayama A, Takada T, Kitajiri S, Wakai K, Suzuki H, Shinomiya N.

Drug Metab Pharmacokinet. 2014;29(6):490-2. doi: 10.2133/dmpk.DMPK-14-SC-041. Epub 2014 May 27.

11.

Genetic variation in the ABCG2 gene is associated with gout risk in the Chinese Han population.

Jiri M, Zhang L, Lan B, He N, Feng T, Liu K, Jin T, Kang L.

Clin Rheumatol. 2016 Jan;35(1):159-63. doi: 10.1007/s10067-015-3105-9. Epub 2015 Oct 27.

PMID:
26506822
12.

A strong role for the ABCG2 gene in susceptibility to gout in New Zealand Pacific Island and Caucasian, but not Māori, case and control sample sets.

Phipps-Green AJ, Hollis-Moffatt JE, Dalbeth N, Merriman ME, Topless R, Gow PJ, Harrison AA, Highton J, Jones PB, Stamp LK, Merriman TR.

Hum Mol Genet. 2010 Dec 15;19(24):4813-9. doi: 10.1093/hmg/ddq412. Epub 2010 Sep 21.

PMID:
20858603
13.

Association of functional polymorphism rs2231142 (Q141K) in the ABCG2 gene with serum uric acid and gout in 4 US populations: the PAGE Study.

Zhang L, Spencer KL, Voruganti VS, Jorgensen NW, Fornage M, Best LG, Brown-Gentry KD, Cole SA, Crawford DC, Deelman E, Franceschini N, Gaffo AL, Glenn KR, Heiss G, Jenny NS, Kottgen A, Li Q, Liu K, Matise TC, North KE, Umans JG, Kao WH.

Am J Epidemiol. 2013 May 1;177(9):923-32. doi: 10.1093/aje/kws330. Epub 2013 Apr 3.

14.

Polymorphisms of uric transporter proteins in the pathogenesis of gout in a Chinese Han population.

Wan W, Xu X, Zhao DB, Pang YF, Wang YX.

Genet Mol Res. 2015 Mar 30;14(1):2546-50. doi: 10.4238/2015.March.30.13.

15.

ABCG2 is a high-capacity urate transporter and its genetic impairment increases serum uric acid levels in humans.

Nakayama A, Matsuo H, Takada T, Ichida K, Nakamura T, Ikebuchi Y, Ito K, Hosoya T, Kanai Y, Suzuki H, Shinomiya N.

Nucleosides Nucleotides Nucleic Acids. 2011 Dec;30(12):1091-7. doi: 10.1080/15257770.2011.633953.

PMID:
22132962
16.

Influence of the ABCG2 gout risk 141 K allele on urate metabolism during a fructose challenge.

Dalbeth N, House ME, Gamble GD, Pool B, Horne A, Purvis L, Stewart A, Merriman M, Cadzow M, Phipps-Green A, Merriman TR.

Arthritis Res Ther. 2014 Jan 30;16(1):R34. doi: 10.1186/ar4463.

17.

The ABCG2 gene Q141K polymorphism contributes to an increased risk of gout: a meta-analysis of 2185 cases.

Qiu Y, Liu H, Qing Y, Yang M, Tan X, Zhao M, Lin M, Zhou J.

Mod Rheumatol. 2014 Sep;24(5):829-34. doi: 10.3109/14397595.2013.875639. Epub 2014 Feb 5.

PMID:
24499401
18.

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout.

Woodward OM, Köttgen A, Coresh J, Boerwinkle E, Guggino WB, Köttgen M.

Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10338-42. doi: 10.1073/pnas.0901249106. Epub 2009 Jun 8.

19.

ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload.

Matsuo H, Nakayama A, Sakiyama M, Chiba T, Shimizu S, Kawamura Y, Nakashima H, Nakamura T, Takada Y, Oikawa Y, Takada T, Nakaoka H, Abe J, Inoue H, Wakai K, Kawai S, Guang Y, Nakagawa H, Ito T, Niwa K, Yamamoto K, Sakurai Y, Suzuki H, Hosoya T, Ichida K, Shimizu T, Shinomiya N.

Sci Rep. 2014 Jan 20;4:3755. doi: 10.1038/srep03755.

20.

Genetic analysis of ABCG2 and SLC2A9 gene polymorphisms in gouty arthritis in a Korean population.

Kim YS, Kim Y, Park G, Kim SK, Choe JY, Park BL, Kim HS.

Korean J Intern Med. 2015 Nov;30(6):913-20. doi: 10.3904/kjim.2015.30.6.913. Epub 2015 Oct 30.

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