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Items: 1 to 20 of 119

1.

[Function and mechanism of tumor suppressor gene FBW7 in tumorigenesis].

Huang HJ, Zheng F, Xu FP, Liu YH, Zhuang HG.

Zhonghua Bing Li Xue Za Zhi. 2013 Mar;42(3):214-6. doi: 10.3760/cma.j.issn.0529-5807.2013.03.020. Review. Chinese. No abstract available.

PMID:
23769449
2.

MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7.

Xu Y, Sengupta T, Kukreja L, Minella AC.

J Biol Chem. 2010 Nov 5;285(45):34439-46. doi: 10.1074/jbc.M110.152306. Epub 2010 Sep 7.

3.

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.

Yada M, Hatakeyama S, Kamura T, Nishiyama M, Tsunematsu R, Imaki H, Ishida N, Okumura F, Nakayama K, Nakayama KI.

EMBO J. 2004 May 19;23(10):2116-25. Epub 2004 Apr 22.

4.

Recombinant human adenovirus-p53 injection induced apoptosis in hepatocellular carcinoma cell lines mediated by p53-Fbxw7 pathway, which controls c-Myc and cyclin E.

Tu K, Zheng X, Zhou Z, Li C, Zhang J, Gao J, Yao Y, Liu Q.

PLoS One. 2013 Jul 1;8(7):e68574. doi: 10.1371/journal.pone.0068574. Print 2013.

5.

Aberrant regulation of FBW7 in cancer.

Wang L, Ye X, Liu Y, Wei W, Wang Z.

Oncotarget. 2014 Apr 30;5(8):2000-15. Review.

6.

F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.

Sancho R, Jandke A, Davis H, Diefenbacher ME, Tomlinson I, Behrens A.

Gastroenterology. 2010 Sep;139(3):929-41. doi: 10.1053/j.gastro.2010.05.078. Epub 2010 Jun 2.

PMID:
20638938
7.

Tumor suppressor activities of the Fbw7 E3 ubiquitin ligase receptor.

Fuchs SY.

Cancer Biol Ther. 2005 May;4(5):506-8. Epub 2005 May 5. Review.

PMID:
15908780
8.

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.

Welcker M, Orian A, Jin J, Grim JE, Harper JW, Eisenman RN, Clurman BE.

Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):9085-90. Epub 2004 May 18. Erratum in: Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):504. Grim, Jonathan A [corrected to Grim, Jonathan E].

9.

A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.

Welcker M, Orian A, Grim JE, Eisenman RN, Clurman BE.

Curr Biol. 2004 Oct 26;14(20):1852-7. Erratum in: Curr Biol. 2005 Dec;15(24):2285. Grim, Jonathan A [corrected to Grim, Jonathan E].

10.

Fbw7 isoform interaction contributes to cyclin E proteolysis.

Zhang W, Koepp DM.

Mol Cancer Res. 2006 Dec;4(12):935-43.

11.

E3 ubiquitin ligase FBW7α inhibits cholangiocarcinoma cell proliferation by downregulating c-Myc and cyclin E.

Li M, Ouyang L, Zheng Z, Xiang D, Ti A, Li L, Dan Y, Yu C, Li W.

Oncol Rep. 2017 Mar;37(3):1627-1636. doi: 10.3892/or.2017.5432. Epub 2017 Feb 7.

PMID:
28184929
12.

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.

Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W.

Nature. 2011 Mar 3;471(7336):104-9. doi: 10.1038/nature09732.

13.

Role of the ubiquitin ligase Fbw7 in cancer progression.

Cheng Y, Li G.

Cancer Metastasis Rev. 2012 Jun;31(1-2):75-87. doi: 10.1007/s10555-011-9330-z. Review.

PMID:
22124735
14.

Regulating Fbw7 on the road to cancer.

Xu W, Taranets L, Popov N.

Semin Cancer Biol. 2016 Feb;36:62-70. doi: 10.1016/j.semcancer.2015.09.005. Epub 2015 Oct 13. Review.

PMID:
26459133
15.

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

Akhoondi S, Sun D, von der Lehr N, Apostolidou S, Klotz K, Maljukova A, Cepeda D, Fiegl H, Dafou D, Marth C, Mueller-Holzner E, Corcoran M, Dagnell M, Nejad SZ, Nayer BN, Zali MR, Hansson J, Egyhazi S, Petersson F, Sangfelt P, Nordgren H, Grander D, Reed SI, Widschwendter M, Sangfelt O, Spruck C.

Cancer Res. 2007 Oct 1;67(19):9006-12. Erratum in: Cancer Res. 2008 Feb 15;68(4):1245. Dofou, Dimitra [corrected to Dafou, Dimitra].

16.

Opposing functions of Fbxw7 in keratinocyte growth, differentiation and skin tumorigenesis mediated through negative regulation of c-Myc and Notch.

Ishikawa Y, Hosogane M, Okuyama R, Aoyama S, Onoyama I, Nakayama KI, Nakayama K.

Oncogene. 2013 Apr 11;32(15):1921-32. doi: 10.1038/onc.2012.213. Epub 2012 Jun 4.

PMID:
22665065
17.

Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase.

Isobe T, Hattori T, Kitagawa K, Uchida C, Kotake Y, Kosugi I, Oda T, Kitagawa M.

J Biol Chem. 2009 Oct 9;284(41):27766-79. doi: 10.1074/jbc.M109.006809. Epub 2009 Aug 13.

18.

PI3K-dependent phosphorylation of Fbw7 modulates substrate degradation and activity.

Schülein C, Eilers M, Popov N.

FEBS Lett. 2011 Jul 21;585(14):2151-7. doi: 10.1016/j.febslet.2011.05.036. Epub 2011 May 24.

19.

The two faces of FBW7 in cancer drug resistance.

Wang Z, Fukushima H, Gao D, Inuzuka H, Wan L, Lau AW, Liu P, Wei W.

Bioessays. 2011 Nov;33(11):851-9. doi: 10.1002/bies.201100101. Epub 2011 Aug 30. Review.

20.

Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities.

Davis RJ, Welcker M, Clurman BE.

Cancer Cell. 2014 Oct 13;26(4):455-64. doi: 10.1016/j.ccell.2014.09.013. Review.

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