Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 83

1.

Development of flavonoid-based inverse agonists of the key signaling receptor US28 of human cytomegalovirus.

Kralj A, Nguyen MT, Tschammer N, Ocampo N, Gesiotto Q, Heinrich MR, Phanstiel O 4th.

J Med Chem. 2013 Jun 27;56(12):5019-32. doi: 10.1021/jm4003457. Epub 2013 Jun 14.

PMID:
23768434
2.

Synthesis and structure-activity relationship of the first nonpeptidergic inverse agonists for the human cytomegalovirus encoded chemokine receptor US28.

Hulshof JW, Casarosa P, Menge WM, Kuusisto LM, van der Goot H, Smit MJ, de Esch IJ, Leurs R.

J Med Chem. 2005 Oct 6;48(20):6461-71.

PMID:
16190772
3.

Allosteric modulation of the G protein-coupled US28 receptor of human cytomegalovirus: are the small-weight inverse agonist of US28 'camouflaged' agonists?

Tschammer N.

Bioorg Med Chem Lett. 2014 Aug 15;24(16):3744-7. doi: 10.1016/j.bmcl.2014.06.082. Epub 2014 Jul 4.

PMID:
25052428
4.

Identification of the first nonpeptidergic inverse agonist for a constitutively active viral-encoded G protein-coupled receptor.

Casarosa P, Menge WM, Minisini R, Otto C, van Heteren J, Jongejan A, Timmerman H, Moepps B, Kirchhoff F, Mertens T, Smit MJ, Leurs R.

J Biol Chem. 2003 Feb 14;278(7):5172-8. Epub 2002 Nov 26.

5.

Identification of novel allosteric modulators for the G-protein coupled US28 receptor of human cytomegalovirus.

Kralj A, Wetzel A, Mahmoudian S, Stamminger T, Tschammer N, Heinrich MR.

Bioorg Med Chem Lett. 2011 Sep 15;21(18):5446-50. doi: 10.1016/j.bmcl.2011.06.120. Epub 2011 Jul 2.

PMID:
21784633
6.

Synthesis and biological evaluation of biphenyl amides that modulate the US28 receptor.

Kralj A, Kurt E, Tschammer N, Heinrich MR.

ChemMedChem. 2014 Jan;9(1):151-68. doi: 10.1002/cmdc.201300369. Epub 2013 Nov 21.

PMID:
24265151
7.

Identification of novel allosteric nonpeptidergic inhibitors of the human cytomegalovirus-encoded chemokine receptor US28.

Vischer HF, Hulshof JW, Hulscher S, Fratantoni SA, Verheij MH, Victorina J, Smit MJ, de Esch IJ, Leurs R.

Bioorg Med Chem. 2010 Jan 15;18(2):675-88. doi: 10.1016/j.bmc.2009.11.060. Epub 2009 Dec 6.

PMID:
20031418
8.

Synthesis and pharmacological characterization of novel inverse agonists acting on the viral-encoded chemokine receptor US28.

Hulshof JW, Vischer HF, Verheij MH, Fratantoni SA, Smit MJ, de Esch IJ, Leurs R.

Bioorg Med Chem. 2006 Nov 1;14(21):7213-30. Epub 2006 Jul 14.

PMID:
16843661
9.

The carboxy-terminal tail of human cytomegalovirus (HCMV) US28 regulates both chemokine-independent and chemokine-dependent signaling in HCMV-infected cells.

Stropes MP, Schneider OD, Zagorski WA, Miller JL, Miller WE.

J Virol. 2009 Oct;83(19):10016-27. doi: 10.1128/JVI.00354-09. Epub 2009 Jul 15.

10.

The human cytomegalovirus US28 protein is located in endocytic vesicles and undergoes constitutive endocytosis and recycling.

Fraile-Ramos A, Kledal TN, Pelchen-Matthews A, Bowers K, Schwartz TW, Marsh M.

Mol Biol Cell. 2001 Jun;12(6):1737-49.

11.

Human cytomegalovirus chemokine receptor US28 induces migration of cells on a CX3CL1-presenting surface.

Hjortø GM, Kiilerich-Pedersen K, Selmeczi D, Kledal TN, Larsen NB.

J Gen Virol. 2013 May;94(Pt 5):1111-20. doi: 10.1099/vir.0.047290-0. Epub 2013 Jan 9.

PMID:
23303826
12.

Human Cytomegalovirus US28: a functionally selective chemokine binding receptor.

Vomaske J, Nelson JA, Streblow DN.

Infect Disord Drug Targets. 2009 Nov;9(5):548-56. Review.

13.

Human cytomegalovirus-inhibitory flavonoids: studies on antiviral activity and mechanism of action.

Evers DL, Chao CF, Wang X, Zhang Z, Huong SM, Huang ES.

Antiviral Res. 2005 Dec;68(3):124-34. Epub 2005 Sep 15.

PMID:
16188329
14.

Eight flavonoids and their potential as inhibitors of human cytomegalovirus replication.

Cotin S, Calliste CA, Mazeron MC, Hantz S, Duroux JL, Rawlinson WD, Ploy MC, Alain S.

Antiviral Res. 2012 Nov;96(2):181-6. doi: 10.1016/j.antiviral.2012.09.010. Epub 2012 Sep 21.

PMID:
23000494
15.

Constitutive signaling of the human cytomegalovirus-encoded chemokine receptor US28.

Casarosa P, Bakker RA, Verzijl D, Navis M, Timmerman H, Leurs R, Smit MJ.

J Biol Chem. 2001 Jan 12;276(2):1133-7.

16.

The HCMV chemokine receptor US28 is a potential target in vascular disease.

Streblow DN, Orloff SL, Nelson JA.

Curr Drug Targets Infect Disord. 2001 Aug;1(2):151-8. Review.

PMID:
12455411
17.

The human cytomegalovirus-encoded chemokine receptor US28 promotes angiogenesis and tumor formation via cyclooxygenase-2.

Maussang D, Langemeijer E, Fitzsimons CP, Stigter-van Walsum M, Dijkman R, Borg MK, Slinger E, Schreiber A, Michel D, Tensen CP, van Dongen GA, Leurs R, Smit MJ.

Cancer Res. 2009 Apr 1;69(7):2861-9. doi: 10.1158/0008-5472.CAN-08-2487. Epub 2009 Mar 24.

18.

US28 is a potent activator of phospholipase C during HCMV infection of clinically relevant target cells.

Miller WE, Zagorski WA, Brenneman JD, Avery D, Miller JL, O'Connor CM.

PLoS One. 2012;7(11):e50524. doi: 10.1371/journal.pone.0050524. Epub 2012 Nov 29.

19.

The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis.

Waldhoer M, Casarosa P, Rosenkilde MM, Smit MJ, Leurs R, Whistler JL, Schwartz TW.

J Biol Chem. 2003 May 23;278(21):19473-82. Epub 2003 Mar 18.

20.

The human cytomegalovirus-encoded chemokine receptor US28 induces caspase-dependent apoptosis.

Pleskoff O, Casarosa P, Verneuil L, Ainoun F, Beisser P, Smit M, Leurs R, Schneider P, Michelson S, Ameisen JC.

FEBS J. 2005 Aug;272(16):4163-77.

Supplemental Content

Support Center