Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 104

1.
2.
3.

Multidrug resistance-associated protein 1 mediates 15-deoxy-Δ(12,14)-prostaglandin J2-induced expression of glutamate cysteine ligase expression via Nrf2 signaling in human breast cancer cells.

Song NY, Kim DH, Kim EH, Na HK, Kim NJ, Suh YG, Surh YJ.

Chem Res Toxicol. 2011 Aug 15;24(8):1231-41. doi: 10.1021/tx200090n. Epub 2011 Jul 25.

PMID:
21728338
4.

Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway.

Maher JM, Dieter MZ, Aleksunes LM, Slitt AL, Guo G, Tanaka Y, Scheffer GL, Chan JY, Manautou JE, Chen Y, Dalton TP, Yamamoto M, Klaassen CD.

Hepatology. 2007 Nov;46(5):1597-610.

PMID:
17668877
5.

Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2.

Aleksunes LM, Slitt AL, Maher JM, Augustine LM, Goedken MJ, Chan JY, Cherrington NJ, Klaassen CD, Manautou JE.

Toxicol Appl Pharmacol. 2008 Jan 1;226(1):74-83. Epub 2007 Aug 31.

6.

A Txnrd1-dependent metabolic switch alters hepatic lipogenesis, glycogen storage, and detoxification.

Iverson SV, Eriksson S, Xu J, Prigge JR, Talago EA, Meade TA, Meade ES, Capecchi MR, Arnér ES, Schmidt EE.

Free Radic Biol Med. 2013 Oct;63:369-80. doi: 10.1016/j.freeradbiomed.2013.05.028. Epub 2013 Jun 3.

7.

Investigation of the effect of a panel of model hepatotoxins on the Nrf2-Keap1 defence response pathway in CD-1 mice.

Randle LE, Goldring CE, Benson CA, Metcalfe PN, Kitteringham NR, Park BK, Williams DP.

Toxicology. 2008 Jan 20;243(3):249-60. Epub 2007 Oct 23.

PMID:
18078705
8.

Bucillamine induces glutathione biosynthesis via activation of the transcription factor Nrf2.

Wielandt AM, Vollrath V, Farias M, Chianale J.

Biochem Pharmacol. 2006 Aug 14;72(4):455-62. Epub 2006 Jun 27.

PMID:
16806086
9.

Induction of lung glutathione and glutamylcysteine ligase by 1,4-phenylenebis(methylene)selenocyanate and its glutathione conjugate: role of nuclear factor-erythroid 2-related factor 2.

Emmert SW, El-Bayoumy K, Das A, Sun YW, Amin S, Desai D, Aliaga C, Richie JP Jr.

Free Radic Biol Med. 2012 May 15;52(10):2064-71. doi: 10.1016/j.freeradbiomed.2012.03.018. Epub 2012 Apr 17.

10.

Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice.

Reisman SA, Csanaky IL, Aleksunes LM, Klaassen CD.

Toxicol Sci. 2009 May;109(1):31-40. doi: 10.1093/toxsci/kfp047. Epub 2009 Feb 26.

11.

Selective mitochondrial glutathione depletion by ethanol enhances acetaminophen toxicity in rat liver.

Zhao P, Kalhorn TF, Slattery JT.

Hepatology. 2002 Aug;36(2):326-35.

PMID:
12143040
12.

Ajoene, a stable garlic by-product, has an antioxidant effect through Nrf2-mediated glutamate-cysteine ligase induction in HepG2 cells and primary hepatocytes.

Kay HY, Won Yang J, Kim TH, Lee DY, Kang B, Ryu JH, Jeon R, Kim SG.

J Nutr. 2010 Jul;140(7):1211-9. doi: 10.3945/jn.110.121277. Epub 2010 May 12.

13.

Salvianolic acid B protects against acetaminophen hepatotoxicity by inducing Nrf2 and phase II detoxification gene expression via activation of the PI3K and PKC signaling pathways.

Lin M, Zhai X, Wang G, Tian X, Gao D, Shi L, Wu H, Fan Q, Peng J, Liu K, Yao J.

J Pharmacol Sci. 2015 Feb;127(2):203-10. doi: 10.1016/j.jphs.2014.12.010. Epub 2014 Dec 24.

15.

Acetaminophen analog N-acetyl-m-aminophenol, but not its reactive metabolite, N-acetyl-p-benzoquinone imine induces CYP3A activity via inhibition of protein degradation.

Santoh M, Sanoh S, Ohtsuki Y, Ejiri Y, Kotake Y, Ohta S.

Biochem Biophys Res Commun. 2017 May 6;486(3):639-644. doi: 10.1016/j.bbrc.2017.03.073. Epub 2017 Mar 21.

PMID:
28341123
16.

Mechanisms of N-acetyl-p-benzoquinone imine cytotoxicity.

Albano E, Rundgren M, Harvison PJ, Nelson SD, Moldéus P.

Mol Pharmacol. 1985 Sep;28(3):306-11.

PMID:
4033631
17.

Protection by chrysin, apigenin, and luteolin against oxidative stress is mediated by the Nrf2-dependent up-regulation of heme oxygenase 1 and glutamate cysteine ligase in rat primary hepatocytes.

Huang CS, Lii CK, Lin AH, Yeh YW, Yao HT, Li CC, Wang TS, Chen HW.

Arch Toxicol. 2013 Jan;87(1):167-78. doi: 10.1007/s00204-012-0913-4. Epub 2012 Aug 5.

PMID:
22864849
18.
20.

High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes.

Enomoto A, Itoh K, Nagayoshi E, Haruta J, Kimura T, O'Connor T, Harada T, Yamamoto M.

Toxicol Sci. 2001 Jan;59(1):169-77.

PMID:
11134556

Supplemental Content

Support Center