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Items: 1 to 20 of 106

1.

Role of the Nrf2-ARE pathway in liver diseases.

Shin SM, Yang JH, Ki SH.

Oxid Med Cell Longev. 2013;2013:763257. doi: 10.1155/2013/763257. Epub 2013 May 9. Review.

2.

Role of Nrf2 in chronic liver disease.

Tang W, Jiang YF, Ponnusamy M, Diallo M.

World J Gastroenterol. 2014 Sep 28;20(36):13079-87. doi: 10.3748/wjg.v20.i36.13079. Review.

3.

Bilirubin mediated oxidative stress involves antioxidant response activation via Nrf2 pathway.

Qaisiya M, Coda Zabetta CD, Bellarosa C, Tiribelli C.

Cell Signal. 2014 Mar;26(3):512-20. doi: 10.1016/j.cellsig.2013.11.029. Epub 2013 Dec 2.

PMID:
24308969
4.

Betanin, a beetroot component, induces nuclear factor erythroid-2-related factor 2-mediated expression of detoxifying/antioxidant enzymes in human liver cell lines.

Krajka-Kuźniak V, Paluszczak J, Szaefer H, Baer-Dubowska W.

Br J Nutr. 2013 Dec;110(12):2138-49. doi: 10.1017/S0007114513001645. Epub 2013 Jun 17.

PMID:
23769299
5.

Panaxatriol saponins attenuated oxygen-glucose deprivation injury in PC12 cells via activation of PI3K/Akt and Nrf2 signaling pathway.

Huang Y, Yu J, Wan F, Zhang W, Yang H, Wang L, Qi H, Wu C.

Oxid Med Cell Longev. 2014;2014:978034. doi: 10.1155/2014/978034. Epub 2014 May 11.

6.

Activation of the Nrf2-ARE pathway in hepatocytes protects against steatosis in nutritionally induced non-alcoholic steatohepatitis in mice.

Lee LY, Köhler UA, Zhang L, Roenneburg D, Werner S, Johnson JA, Foley DP.

Toxicol Sci. 2014 Dec;142(2):361-74. doi: 10.1093/toxsci/kfu184. Epub 2014 Oct 6.

7.

Fasting induces nuclear factor E2-related factor 2 and ATP-binding Cassette transporters via protein kinase A and Sirtuin-1 in mouse and human.

Kulkarni SR, Donepudi AC, Xu J, Wei W, Cheng QC, Driscoll MV, Johnson DA, Johnson JA, Li X, Slitt AL.

Antioxid Redox Signal. 2014 Jan 1;20(1):15-30. doi: 10.1089/ars.2012.5082. Epub 2013 Jul 31.

8.

Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease.

Aleksunes LM, Manautou JE.

Toxicol Pathol. 2007 Jun;35(4):459-73. Review.

9.

The role of Nrf2 in oxidative stress-induced endothelial injuries.

Chen B, Lu Y, Chen Y, Cheng J.

J Endocrinol. 2015 Jun;225(3):R83-99. doi: 10.1530/JOE-14-0662. Epub 2015 Apr 27. Review.

10.

Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases.

Gan L, Johnson JA.

Biochim Biophys Acta. 2014 Aug;1842(8):1208-18. doi: 10.1016/j.bbadis.2013.12.011. Epub 2013 Dec 29. Review.

11.

A novel small molecule, N-(4-(2-pyridyl)(1,3-thiazol-2-yl))-2-(2,4,6-trimethylphenoxy) acetamide, selectively protects against oxidative stress-induced cell death by activating the Nrf2-ARE pathway: therapeutic implications for ALS.

Kanno T, Tanaka K, Yanagisawa Y, Yasutake K, Hadano S, Yoshii F, Hirayama N, Ikeda JE.

Free Radic Biol Med. 2012 Dec 1;53(11):2028-42. doi: 10.1016/j.freeradbiomed.2012.09.010. Epub 2012 Sep 20.

PMID:
23000247
12.

Role of the Nrf2 signaling system in health and disease.

Hybertson BM, Gao B.

Clin Genet. 2014 Nov;86(5):447-52. doi: 10.1111/cge.12474. Epub 2014 Sep 16. Review.

PMID:
25099075
13.

Implementation of a high-throughput screen for identifying small molecules to activate the Keap1-Nrf2-ARE pathway.

Wu KC, McDonald PR, Liu JJ, Chaguturu R, Klaassen CD.

PLoS One. 2012;7(10):e44686. doi: 10.1371/journal.pone.0044686. Epub 2012 Oct 8.

14.

The Nrf2-antioxidant response element pathway: a target for regulating energy metabolism.

Vomhof-Dekrey EE, Picklo MJ Sr.

J Nutr Biochem. 2012 Oct;23(10):1201-6. doi: 10.1016/j.jnutbio.2012.03.005. Epub 2012 Jul 21. Review.

PMID:
22819548
15.

Over-expression of Nrf2 diminishes ethanol-induced oxidative stress and apoptosis in neural crest cells by inducing an antioxidant response.

Chen X, Liu J, Chen SY.

Reprod Toxicol. 2013 Dec;42:102-9. doi: 10.1016/j.reprotox.2013.08.003. Epub 2013 Aug 27.

16.

Licochalcone E activates Nrf2/antioxidant response element signaling pathway in both neuronal and microglial cells: therapeutic relevance to neurodegenerative disease.

Kim SS, Lim J, Bang Y, Gal J, Lee SU, Cho YC, Yoon G, Kang BY, Cheon SH, Choi HJ.

J Nutr Biochem. 2012 Oct;23(10):1314-23. doi: 10.1016/j.jnutbio.2011.07.012. Epub 2012 Jan 5.

PMID:
22227268
17.

Dietary Lycium barbarum polysaccharide induces Nrf2/ARE pathway and ameliorates insulin resistance induced by high-fat via activation of PI3K/AKT signaling.

Yang Y, Li W, Li Y, Wang Q, Gao L, Zhao J.

Oxid Med Cell Longev. 2014;2014:145641. doi: 10.1155/2014/145641. Epub 2014 Jun 22.

18.

The Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseases.

Joshi G, Johnson JA.

Recent Pat CNS Drug Discov. 2012 Dec;7(3):218-29. Review.

19.

Dimethyl fumarate attenuates 6-OHDA-induced neurotoxicity in SH-SY5Y cells and in animal model of Parkinson's disease by enhancing Nrf2 activity.

Jing X, Shi H, Zhang C, Ren M, Han M, Wei X, Zhang X, Lou H.

Neuroscience. 2015 Feb 12;286:131-40. doi: 10.1016/j.neuroscience.2014.11.047. Epub 2014 Nov 29.

PMID:
25449120
20.

Nrf2 activates augmenter of liver regeneration (ALR) via antioxidant response element and links oxidative stress to liver regeneration.

Dayoub R, Vogel A, Schuett J, Lupke M, Spieker SM, Kettern N, Hildt E, Melter M, Weiss TS.

Mol Med. 2013 Aug 28;19:237-44. doi: 10.2119/molmed.2013.00027.

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