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Items: 1 to 20 of 136

1.

Direct transcriptional reprogramming of adult cells to embryonic nephron progenitors.

Hendry CE, Vanslambrouck JM, Ineson J, Suhaimi N, Takasato M, Rae F, Little MH.

J Am Soc Nephrol. 2013 Sep;24(9):1424-34. doi: 10.1681/ASN.2012121143. Epub 2013 Jun 13.

2.

Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesis.

Xu J, Liu H, Park JS, Lan Y, Jiang R.

Development. 2014 Apr;141(7):1442-52. doi: 10.1242/dev.103283. Epub 2014 Mar 5.

3.
4.

Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development.

Kobayashi A, Valerius MT, Mugford JW, Carroll TJ, Self M, Oliver G, McMahon AP.

Cell Stem Cell. 2008 Aug 7;3(2):169-81. doi: 10.1016/j.stem.2008.05.020.

5.

Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators.

O'Brien LL, Guo Q, Lee Y, Tran T, Benazet JD, Whitney PH, Valouev A, McMahon AP.

Development. 2016 Feb 15;143(4):595-608. doi: 10.1242/dev.127175.

6.

Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor.

Kanda S, Tanigawa S, Ohmori T, Taguchi A, Kudo K, Suzuki Y, Sato Y, Hino S, Sander M, Perantoni AO, Sugano S, Nakao M, Nishinakamura R.

J Am Soc Nephrol. 2014 Nov;25(11):2584-95. doi: 10.1681/ASN.2013080896. Epub 2014 Apr 17.

7.

Notch2 activation in the embryonic kidney depletes nephron progenitors.

Fujimura S, Jiang Q, Kobayashi C, Nishinakamura R.

J Am Soc Nephrol. 2010 May;21(5):803-10. doi: 10.1681/ASN.2009040353. Epub 2010 Mar 18.

8.

p53 Enables metabolic fitness and self-renewal of nephron progenitor cells.

Li Y, Liu J, Li W, Brown A, Baddoo M, Li M, Carroll T, Oxburgh L, Feng Y, Saifudeen Z.

Development. 2015 Apr 1;142(7):1228-41. doi: 10.1242/dev.111617.

9.

Mdm2 is required for maintenance of the nephrogenic niche.

Hilliard SA, Yao X, El-Dahr SS.

Dev Biol. 2014 Mar 1;387(1):1-14. doi: 10.1016/j.ydbio.2014.01.009. Epub 2014 Jan 17.

10.

Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development.

Karner CM, Das A, Ma Z, Self M, Chen C, Lum L, Oliver G, Carroll TJ.

Development. 2011 Apr;138(7):1247-57. doi: 10.1242/dev.057646. Epub 2011 Feb 24.

11.

Notch signaling promotes nephrogenesis by downregulating Six2.

Chung E, Deacon P, Marable S, Shin J, Park JS.

Development. 2016 Nov 1;143(21):3907-3913. Epub 2016 Sep 15.

12.

Eya1 interacts with Six2 and Myc to regulate expansion of the nephron progenitor pool during nephrogenesis.

Xu J, Wong EY, Cheng C, Li J, Sharkar MT, Xu CY, Chen B, Sun J, Jing D, Xu PX.

Dev Cell. 2014 Nov 24;31(4):434-47. doi: 10.1016/j.devcel.2014.10.015. Epub 2014 Nov 24.

13.

Nephron progenitor cells: shifting the balance of self-renewal and differentiation.

Kopan R, Chen S, Little M.

Curr Top Dev Biol. 2014;107:293-331. doi: 10.1016/B978-0-12-416022-4.00011-1. Review.

PMID:
24439811
14.
15.

Prorenin receptor is critical for nephron progenitors.

Song R, Preston G, Kidd L, Bushnell D, Sims-Lucas S, Bates CM, Yosypiv IV.

Dev Biol. 2016 Jan 15;409(2):382-91. doi: 10.1016/j.ydbio.2015.11.024. Epub 2015 Dec 3.

16.

Epigenetic States of nephron progenitors and epithelial differentiation.

Adli M, Parlak M, Li Y, El-Dahr SS.

J Cell Biochem. 2015 Jun;116(6):893-902. doi: 10.1002/jcb.25048. Review.

17.

The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage.

Surendran K, Boyle S, Barak H, Kim M, Stomberski C, McCright B, Kopan R.

Dev Biol. 2010 Jan 15;337(2):386-95. doi: 10.1016/j.ydbio.2009.11.017. Epub 2009 Nov 13.

18.

Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease.

Harari-Steinberg O, Metsuyanim S, Omer D, Gnatek Y, Gershon R, Pri-Chen S, Ozdemir DD, Lerenthal Y, Noiman T, Ben-Hur H, Vaknin Z, Schneider DF, Aronow BJ, Goldstein RS, Hohenstein P, Dekel B.

EMBO Mol Med. 2013 Oct;5(10):1556-68. doi: 10.1002/emmm.201201584. Epub 2013 Sep 2.

19.

Microarrays and RNA-Seq identify molecular mechanisms driving the end of nephron production.

Brunskill EW, Lai HL, Jamison DC, Potter SS, Patterson LT.

BMC Dev Biol. 2011 Mar 12;11:15. doi: 10.1186/1471-213X-11-15.

20.

Nephron formation adopts a novel spatial topology at cessation of nephrogenesis.

Rumballe BA, Georgas KM, Combes AN, Ju AL, Gilbert T, Little MH.

Dev Biol. 2011 Dec 1;360(1):110-22. doi: 10.1016/j.ydbio.2011.09.011. Epub 2011 Sep 21.

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