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Items: 1 to 20 of 166

1.

Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion.

Klett EL, Chen S, Edin ML, Li LO, Ilkayeva O, Zeldin DC, Newgard CB, Coleman RA.

J Biol Chem. 2013 Jul 26;288(30):21618-29. doi: 10.1074/jbc.M113.481077. Epub 2013 Jun 13.

2.

Characterization of Acyl-CoA synthetase isoforms in pancreatic beta cells: Gene silencing shows participation of ACSL3 and ACSL4 in insulin secretion.

Ansari IH, Longacre MJ, Stoker SW, Kendrick MA, O'Neill LM, Zitur LJ, Fernandez LA, Ntambi JM, MacDonald MJ.

Arch Biochem Biophys. 2017 Mar 15;618:32-43. doi: 10.1016/j.abb.2017.02.001. Epub 2017 Feb 11.

PMID:
28193492
3.

Hepatic long-chain acyl-CoA synthetase 5 mediates fatty acid channeling between anabolic and catabolic pathways.

Bu SY, Mashek DG.

J Lipid Res. 2010 Nov;51(11):3270-80. doi: 10.1194/jlr.M009407. Epub 2010 Aug 26.

4.

Elevated insulin secretion from liver X receptor-activated pancreatic beta-cells involves increased de novo lipid synthesis and triacylglyceride turnover.

Green CD, Jump DB, Olson LK.

Endocrinology. 2009 Jun;150(6):2637-45. doi: 10.1210/en.2008-1039. Epub 2009 Feb 19.

5.

Role of long-chain acyl-coenzyme A synthetases in the regulation of arachidonic acid metabolism in interleukin 1β-stimulated rat fibroblasts.

Kuwata H, Yoshimura M, Sasaki Y, Yoda E, Nakatani Y, Kudo I, Hara S.

Biochim Biophys Acta. 2014 Jan;1841(1):44-53. doi: 10.1016/j.bbalip.2013.09.015. Epub 2013 Oct 1.

PMID:
24095834
6.

Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion.

Herrero L, Rubí B, Sebastián D, Serra D, Asins G, Maechler P, Prentki M, Hegardt FG.

Diabetes. 2005 Feb;54(2):462-71.

7.

Long-chain acyl-CoA synthetase 4 modulates prostaglandin E₂ release from human arterial smooth muscle cells.

Golej DL, Askari B, Kramer F, Barnhart S, Vivekanandan-Giri A, Pennathur S, Bornfeldt KE.

J Lipid Res. 2011 Apr;52(4):782-93. doi: 10.1194/jlr.M013292. Epub 2011 Jan 17.

8.

Distinct transcriptional regulation of long-chain acyl-CoA synthetase isoforms and cytosolic thioesterase 1 in the rodent heart by fatty acids and insulin.

Durgan DJ, Smith JK, Hotze MA, Egbejimi O, Cuthbert KD, Zaha VG, Dyck JR, Abel ED, Young ME.

Am J Physiol Heart Circ Physiol. 2006 Jun;290(6):H2480-97. Epub 2006 Jan 20.

9.

Functional interaction between acyl-CoA synthetase 4, lipooxygenases and cyclooxygenase-2 in the aggressive phenotype of breast cancer cells.

Maloberti PM, Duarte AB, Orlando UD, Pasqualini ME, Solano AR, López-Otín C, Podestá EJ.

PLoS One. 2010 Nov 11;5(11):e15540. doi: 10.1371/journal.pone.0015540.

10.

Increased glucose metabolism and glycerolipid formation by fatty acids and GPR40 receptor signaling underlies the fatty acid potentiation of insulin secretion.

El-Azzouny M, Evans CR, Treutelaar MK, Kennedy RT, Burant CF.

J Biol Chem. 2014 May 9;289(19):13575-88. doi: 10.1074/jbc.M113.531970. Epub 2014 Mar 27.

11.

Transcriptional co-activator peroxisome proliferator-activated receptor (PPAR)gamma co-activator-1beta is involved in the regulation of glucose-stimulated insulin secretion in INS-1E cells.

Oberkofler H, Hafner M, Felder T, Krempler F, Patsch W.

J Mol Med (Berl). 2009 Mar;87(3):299-306. doi: 10.1007/s00109-008-0425-0. Epub 2008 Dec 11.

PMID:
19082571
13.

Rat long chain acyl-CoA synthetase 5 increases fatty acid uptake and partitioning to cellular triacylglycerol in McArdle-RH7777 cells.

Mashek DG, McKenzie MA, Van Horn CG, Coleman RA.

J Biol Chem. 2006 Jan 13;281(2):945-50. Epub 2005 Nov 1.

14.

Normal flux through ATP-citrate lyase or fatty acid synthase is not required for glucose-stimulated insulin secretion.

Joseph JW, Odegaard ML, Ronnebaum SM, Burgess SC, Muehlbauer J, Sherry AD, Newgard CB.

J Biol Chem. 2007 Oct 26;282(43):31592-600. Epub 2007 Sep 6.

15.

Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells.

Mulder H, Lu D, Finley J 4th, An J, Cohen J, Antinozzi PA, McGarry JD, Newgard CB.

J Biol Chem. 2001 Mar 2;276(9):6479-84. Epub 2000 Dec 11.

16.

Rat long-chain acyl-CoA synthetase mRNA, protein, and activity vary in tissue distribution and in response to diet.

Mashek DG, Li LO, Coleman RA.

J Lipid Res. 2006 Sep;47(9):2004-10. Epub 2006 Jun 13.

17.

Reactive oxygen species stimulate insulin secretion in rat pancreatic islets: studies using mono-oleoyl-glycerol.

Saadeh M, Ferrante TC, Kane A, Shirihai O, Corkey BE, Deeney JT.

PLoS One. 2012;7(1):e30200. doi: 10.1371/journal.pone.0030200. Epub 2012 Jan 17.

18.

Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism.

Ronnebaum SM, Joseph JW, Ilkayeva O, Burgess SC, Lu D, Becker TC, Sherry AD, Newgard CB.

J Biol Chem. 2008 May 23;283(21):14248-56. doi: 10.1074/jbc.M800119200. Epub 2008 Apr 1.

19.

Chronic leucine exposure results in reduced but reversible glucose-stimulated insulin secretion in INS-1 cells.

Zhang X, Han W, Jiang X, Li M, Gao L, Zhao JJ.

Mol Med Rep. 2014 Jun;9(6):2554-8. doi: 10.3892/mmr.2014.2122. Epub 2014 Apr 8.

PMID:
24715028
20.

PPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunction.

Ravnskjaer K, Frigerio F, Boergesen M, Nielsen T, Maechler P, Mandrup S.

J Lipid Res. 2010 Jun;51(6):1370-9. doi: 10.1194/jlr.M001123. Epub 2009 Nov 30.

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