Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 171


Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation.

Sun C, Querol-Audí J, Mortimer SA, Arias-Palomo E, Doudna JA, Nogales E, Cate JH.

Nucleic Acids Res. 2013 Aug;41(15):7512-21. doi: 10.1093/nar/gkt510. Epub 2013 Jun 13.


Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit.

Hashem Y, des Georges A, Dhote V, Langlois R, Liao HY, Grassucci RA, Pestova TV, Hellen CU, Frank J.

Nature. 2013 Nov 28;503(7477):539-43. doi: 10.1038/nature12658. Epub 2013 Nov 3.


Distinct regions of human eIF3 are sufficient for binding to the HCV IRES and the 40S ribosomal subunit.

Cai Q, Todorovic A, Andaya A, Gao J, Leary JA, Cate JH.

J Mol Biol. 2010 Oct 22;403(2):185-96. doi: 10.1016/j.jmb.2010.07.054. Epub 2010 Sep 15.


Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA.

Ji H, Fraser CS, Yu Y, Leary J, Doudna JA.

Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):16990-5. Epub 2004 Nov 24.


The interaction between human initiation factor eIF3 subunit c and heat-shock protein 90: a necessary factor for translation mediated by the hepatitis C virus internal ribosome entry site.

Ujino S, Nishitsuji H, Sugiyama R, Suzuki H, Hishiki T, Sugiyama K, Shimotohno K, Takaku H.

Virus Res. 2012 Jan;163(1):390-5. doi: 10.1016/j.virusres.2011.10.003. Epub 2011 Oct 14.


HCV IRES domain IIb affects the configuration of coding RNA in the 40S subunit's decoding groove.

Filbin ME, Kieft JS.

RNA. 2011 Jul;17(7):1258-73. doi: 10.1261/rna.2594011. Epub 2011 May 23.


Components of the multifactor complex needed for internal initiation by the IRES of hepatitis C virus in Saccharomyces cerevisiae.

Rosenfeld AB, Racaniello VR.

RNA Biol. 2010 Sep-Oct;7(5):596-605. doi: 10.4161/rna.7.5.13096. Epub 2010 Sep 1.


Structural and mechanistic insights into hepatitis C viral translation initiation.

Fraser CS, Doudna JA.

Nat Rev Microbiol. 2007 Jan;5(1):29-38. Epub 2006 Nov 27. Review.


IGF2BP1 enhances HCV IRES-mediated translation initiation via the 3'UTR.

Weinlich S, Hüttelmaier S, Schierhorn A, Behrens SE, Ostareck-Lederer A, Ostareck DH.

RNA. 2009 Aug;15(8):1528-42. doi: 10.1261/rna.1578409. Epub 2009 Jun 18.


Human initiation factor eIF3 subunit b interacts with HCV IRES RNA through its N-terminal RNA recognition motif.

Pérard J, Rasia R, Medenbach J, Ayala I, Boisbouvier J, Drouet E, Baudin F.

FEBS Lett. 2009 Jan 5;583(1):70-4. doi: 10.1016/j.febslet.2008.11.025. Epub 2008 Dec 6.


LOOP IIId of the HCV IRES is essential for the structural rearrangement of the 40S-HCV IRES complex.

Angulo J, Ulryck N, Deforges J, Chamond N, Lopez-Lastra M, Masquida B, Sargueil B.

Nucleic Acids Res. 2016 Feb 18;44(3):1309-25. doi: 10.1093/nar/gkv1325. Epub 2015 Nov 30.


Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3).

Sun C, Todorovic A, Querol-Audí J, Bai Y, Villa N, Snyder M, Ashchyan J, Lewis CS, Hartland A, Gradia S, Fraser CS, Doudna JA, Nogales E, Cate JH.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20473-8. doi: 10.1073/pnas.1116821108. Epub 2011 Dec 1.


Mechanism of ribosome recruitment by hepatitis C IRES RNA.

Kieft JS, Zhou K, Jubin R, Doudna JA.

RNA. 2001 Feb;7(2):194-206.


Structural roles for human translation factor eIF3 in initiation of protein synthesis.

Siridechadilok B, Fraser CS, Hall RJ, Doudna JA, Nogales E.

Science. 2005 Dec 2;310(5753):1513-5.


A new role for PGA1 in inhibiting hepatitis C virus-IRES-mediated translation by targeting viral translation factors.

Tsukimoto A, Sugiyama R, Abe M, Nishitsuji H, Shimizu Y, Shimotohno K, Kawai G, Takaku H.

Antiviral Res. 2015 May;117:1-9. doi: 10.1016/j.antiviral.2015.01.013. Epub 2015 Feb 7.


The pathway of HCV IRES-mediated translation initiation.

Otto GA, Puglisi JD.

Cell. 2004 Oct 29;119(3):369-80.


The HCV IRES pseudoknot positions the initiation codon on the 40S ribosomal subunit.

Berry KE, Waghray S, Doudna JA.

RNA. 2010 Aug;16(8):1559-69. doi: 10.1261/rna.2197210. Epub 2010 Jun 28.

Supplemental Content

Support Center