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Items: 1 to 20 of 104


Stimulation of somatic cell reprogramming by ERas-Akt-FoxO1 signaling axis.

Yu Y, Liang D, Tian Q, Chen X, Jiang B, Chou BK, Hu P, Cheng L, Gao P, Li J, Wang G.

Stem Cells. 2014 Feb;32(2):349-63. doi: 10.1002/stem.1447.


The Role of Embryonic Stem Cell-expressed RAS (ERAS) in the Maintenance of Quiescent Hepatic Stellate Cells.

Nakhaei-Rad S, Nakhaeizadeh H, Götze S, Kordes C, Sawitza I, Hoffmann MJ, Franke M, Schulz WA, Scheller J, Piekorz RP, Häussinger D, Ahmadian MR.

J Biol Chem. 2016 Apr 15;291(16):8399-413. doi: 10.1074/jbc.M115.700088. Epub 2016 Feb 16.


FOXO1 is an essential regulator of pluripotency in human embryonic stem cells.

Zhang X, Yalcin S, Lee DF, Yeh TY, Lee SM, Su J, Mungamuri SK, Rimmelé P, Kennedy M, Sellers R, Landthaler M, Tuschl T, Chi NW, Lemischka I, Keller G, Ghaffari S.

Nat Cell Biol. 2011 Jul 31;13(9):1092-9. doi: 10.1038/ncb2293.


Helicobacter pylori-associated regulation of forkhead transcription factors FoxO1/3a in human gastric cells.

Tabassam FH, Graham DY, Yamaoka Y.

Helicobacter. 2012 Jun;17(3):193-202. doi: 10.1111/j.1523-5378.2012.00939.x. Epub 2012 Mar 20.


The roles of ERAS during cell lineage specification of mouse early embryonic development.

Zhao ZA, Yu Y, Ma HX, Wang XX, Lu X, Zhai Y, Zhang X, Wang H, Li L.

Open Biol. 2015 Aug;5(8). pii: 150092. doi: 10.1098/rsob.150092.


Foxo1 is required in mouse spermatogonial stem cells for their maintenance and the initiation of spermatogenesis.

Goertz MJ, Wu Z, Gallardo TD, Hamra FK, Castrillon DH.

J Clin Invest. 2011 Sep;121(9):3456-66. doi: 10.1172/JCI57984. Epub 2011 Aug 25.


Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway.

Tan SH, Shui G, Zhou J, Shi Y, Huang J, Xia D, Wenk MR, Shen HM.

Autophagy. 2014 Feb;10(2):226-42. doi: 10.4161/auto.27003. Epub 2013 Nov 26.


Sox2 expression is regulated by a negative feedback loop in embryonic stem cells that involves AKT signaling and FoxO1.

Ormsbee Golden BD, Wuebben EL, Rizzino A.

PLoS One. 2013 Oct 8;8(10):e76345. doi: 10.1371/journal.pone.0076345. eCollection 2013.


Regulation of cardiomyocyte proliferation and myocardial growth during development by FOXO transcription factors.

Evans-Anderson HJ, Alfieri CM, Yutzey KE.

Circ Res. 2008 Mar 28;102(6):686-94. doi: 10.1161/CIRCRESAHA.107.163428. Epub 2008 Jan 24.


Differential effects of Akt isoforms on somatic cell reprogramming.

Tang Y, Jiang Z, Luo Y, Zhao X, Wang L, Norris C, Tian XC.

J Cell Sci. 2014 Sep 15;127(Pt 18):3998-4008. doi: 10.1242/jcs.150029. Epub 2014 Jul 18.


Valproic acid induces monoamine oxidase A via Akt/forkhead box O1 activation.

Wu JB, Shih JC.

Mol Pharmacol. 2011 Oct;80(4):714-23. doi: 10.1124/mol.111.072744. Epub 2011 Jul 20.


TNF induction of atrogin-1/MAFbx mRNA depends on Foxo4 expression but not AKT-Foxo1/3 signaling.

Moylan JS, Smith JD, Chambers MA, McLoughlin TJ, Reid MB.

Am J Physiol Cell Physiol. 2008 Oct;295(4):C986-93. doi: 10.1152/ajpcell.00041.2008. Epub 2008 Aug 13.


Regulation of forkhead box O1 (FOXO1) by protein kinase B and glucocorticoids: different mechanisms of induction of beta cell death in vitro.

Kaiser G, Gerst F, Michael D, Berchtold S, Friedrich B, Strutz-Seebohm N, Lang F, Häring HU, Ullrich S.

Diabetologia. 2013 Jul;56(7):1587-95. doi: 10.1007/s00125-013-2863-7. Epub 2013 Feb 23.


PTEN-mediated Akt/β-catenin/Foxo1 signaling regulates innate immune responses in mouse liver ischemia/reperfusion injury.

Kamo N, Ke B, Busuttil RW, Kupiec-Weglinski JW.

Hepatology. 2013 Jan;57(1):289-98. doi: 10.1002/hep.25958. Epub 2012 Dec 4.


LRP16 gene protects mouse insulinoma MIN6 cells against fatty acid-induced apoptosis through Akt/FoxO1 signaling.

Li XJ, Guo QH, Wang X, Xue B, Sun LQ, Meng QT, Lu JM, Mu YM.

Chin Med J (Engl). 2012 May;125(10):1695-702.


FoxO3a contributes to the reprogramming process and the differentiation of induced pluripotent stem cells.

Wang Y, Tian C, Zheng JC.

Stem Cells Dev. 2013 Nov 15;22(22):2954-63. doi: 10.1089/scd.2013.0044. Epub 2013 Aug 9.


Inhibition of FOXO1/3 promotes vascular calcification.

Deng L, Huang L, Sun Y, Heath JM, Wu H, Chen Y.

Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):175-83. doi: 10.1161/ATVBAHA.114.304786. Epub 2014 Nov 6.


Hepatocyte growth factor inhibits VEGF-forkhead-dependent gene expression in endothelial cells.

Abid MR, Nadeau RJ, Spokes KC, Minami T, Li D, Shih SC, Aird WC.

Arterioscler Thromb Vasc Biol. 2008 Nov;28(11):2042-8. doi: 10.1161/ATVBAHA.108.175109. Epub 2008 Sep 11.


Residual expression of reprogramming factors affects the transcriptional program and epigenetic signatures of induced pluripotent stem cells.

Sommer CA, Christodoulou C, Gianotti-Sommer A, Shen SS, Sailaja BS, Hezroni H, Spira A, Meshorer E, Kotton DN, Mostoslavsky G.

PLoS One. 2012;7(12):e51711. doi: 10.1371/journal.pone.0051711. Epub 2012 Dec 14.


miR-34 miRNAs provide a barrier for somatic cell reprogramming.

Choi YJ, Lin CP, Ho JJ, He X, Okada N, Bu P, Zhong Y, Kim SY, Bennett MJ, Chen C, Ozturk A, Hicks GG, Hannon GJ, He L.

Nat Cell Biol. 2011 Oct 23;13(11):1353-60. doi: 10.1038/ncb2366.

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