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Items: 1 to 20 of 92

1.

NKX2-1/TTF-1: an enigmatic oncogene that functions as a double-edged sword for cancer cell survival and progression.

Yamaguchi T, Hosono Y, Yanagisawa K, Takahashi T.

Cancer Cell. 2013 Jun 10;23(6):718-23. doi: 10.1016/j.ccr.2013.04.002. Review.

2.

Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1).

Runkle EA, Rice SJ, Qi J, Masser D, Antonetti DA, Winslow MM, Mu D.

J Biol Chem. 2012 Aug 17;287(34):28790-801. doi: 10.1074/jbc.M112.367987. Epub 2012 Jul 2.

3.

The complexity of thyroid transcription factor 1 with both pro- and anti-oncogenic activities.

Mu D.

J Biol Chem. 2013 Aug 30;288(35):24992-5000. doi: 10.1074/jbc.R113.491647. Epub 2013 Jul 1. Review.

4.

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung.

Maeda Y, Tsuchiya T, Hao H, Tompkins DH, Xu Y, Mucenski ML, Du L, Keiser AR, Fukazawa T, Naomoto Y, Nagayasu T, Whitsett JA.

J Clin Invest. 2012 Dec;122(12):4388-400. doi: 10.1172/JCI64048. Epub 2012 Nov 12.

5.

NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma.

Yamaguchi T, Yanagisawa K, Sugiyama R, Hosono Y, Shimada Y, Arima C, Kato S, Tomida S, Suzuki M, Osada H, Takahashi T.

Cancer Cell. 2012 Mar 20;21(3):348-61. doi: 10.1016/j.ccr.2012.02.008.

6.

Nkx2-1: a novel tumor biomarker of lung cancer.

Yang L, Lin M, Ruan WJ, Dong LL, Chen EG, Wu XH, Ying KJ.

J Zhejiang Univ Sci B. 2012 Nov;13(11):855-66. doi: 10.1631/jzus.B1100382. Review.

7.

Suppression of lung adenocarcinoma progression by Nkx2-1.

Winslow MM, Dayton TL, Verhaak RG, Kim-Kiselak C, Snyder EL, Feldser DM, Hubbard DD, DuPage MJ, Whittaker CA, Hoersch S, Yoon S, Crowley D, Bronson RT, Chiang DY, Meyerson M, Jacks T.

Nature. 2011 May 5;473(7345):101-4. doi: 10.1038/nature09881. Epub 2011 Apr 6.

8.

Thyroid transcription factor-1 (TTF-1/Nkx2.1/TITF1) gene regulation in the lung.

Boggaram V.

Clin Sci (Lond). 2009 Jan;116(1):27-35. doi: 10.1042/CS20080068. Review.

PMID:
19037882
9.

Thyroid transcription factor-1.

Bingle CD.

Int J Biochem Cell Biol. 1997 Dec;29(12):1471-3. Review.

PMID:
9570141
10.

Genome-wide analyses of Nkx2-1 binding to transcriptional target genes uncover novel regulatory patterns conserved in lung development and tumors.

Tagne JB, Gupta S, Gower AC, Shen SS, Varma S, Lakshminarayanan M, Cao Y, Spira A, Volkert TL, Ramirez MI.

PLoS One. 2012;7(1):e29907. doi: 10.1371/journal.pone.0029907. Epub 2012 Jan 5.

11.

Lineage-specific dependency of lung adenocarcinomas on the lung development regulator TTF-1.

Tanaka H, Yanagisawa K, Shinjo K, Taguchi A, Maeno K, Tomida S, Shimada Y, Osada H, Kosaka T, Matsubara H, Mitsudomi T, Sekido Y, Tanimoto M, Yatabe Y, Takahashi T.

Cancer Res. 2007 Jul 1;67(13):6007-11.

12.

TTF-1 phosphorylation is required for peripheral lung morphogenesis, perinatal survival, and tissue-specific gene expression.

DeFelice M, Silberschmidt D, DiLauro R, Xu Y, Wert SE, Weaver TE, Bachurski CJ, Clark JC, Whitsett JA.

J Biol Chem. 2003 Sep 12;278(37):35574-83. Epub 2003 Jun 26.

13.

[Research progress of thyroid transcription factor-1 as molecular marker in lung carcinoma].

Ge X, Jiang L.

Zhongguo Fei Ai Za Zhi. 2014 Jun 20;17(6):491-5. doi: 10.3779/j.issn.1009-3419.2014.06.10. Review. Chinese.

14.

Opposite roles of FOXA1 and NKX2-1 in lung cancer progression.

Deutsch L, Wrage M, Koops S, Glatzel M, Uzunoglu FG, Kutup A, Hinsch A, Sauter G, Izbicki JR, Pantel K, Wikman H.

Genes Chromosomes Cancer. 2012 Jun;51(6):618-29. doi: 10.1002/gcc.21950. Epub 2012 Mar 2.

PMID:
22383183
15.

Developmental expression of the Xenopus Nkx2-1 and Nkx2-4 genes.

Small EM, Vokes SA, Garriock RJ, Li D, Krieg PA.

Mech Dev. 2000 Sep;96(2):259-62.

PMID:
10960795
16.

Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.

Snyder EL, Watanabe H, Magendantz M, Hoersch S, Chen TA, Wang DG, Crowley D, Whittaker CA, Meyerson M, Kimura S, Jacks T.

Mol Cell. 2013 Apr 25;50(2):185-99. doi: 10.1016/j.molcel.2013.02.018. Epub 2013 Mar 21.

17.
18.

Obligate progression precedes lung adenocarcinoma dissemination.

Caswell DR, Chuang CH, Yang D, Chiou SH, Cheemalavagu S, Kim-Kiselak C, Connolly A, Winslow MM.

Cancer Discov. 2014 Jul;4(7):781-9. doi: 10.1158/2159-8290.CD-13-0862. Epub 2014 Apr 16.

19.

TTF-1 is an epithelial morphoregulatory transcriptional factor.

Minoo P, Li C, Liu HB, Hamdan H, deLemos R.

Chest. 1997 Jun;111(6 Suppl):135S-137S. No abstract available.

PMID:
9184563
20.
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