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Items: 1 to 20 of 89

1.

Unintended effects of cardiovascular drugs on the pathogenesis of Alzheimer's disease.

Wang J, Zhao Z, Lin E, Zhao W, Qian X, Freire D, Bilski AE, Cheng A, Vempati P, Ho L, Ono K, Yamada M, Pasinetti GM.

PLoS One. 2013 Jun 6;8(6):e65232. doi: 10.1371/journal.pone.0065232. Print 2013.

2.

Phenylbutyric acid reduces amyloid plaques and rescues cognitive behavior in AD transgenic mice.

Wiley JC, Pettan-Brewer C, Ladiges WC.

Aging Cell. 2011 Jun;10(3):418-28. doi: 10.1111/j.1474-9726.2011.00680.x. Epub 2011 Mar 22.

3.

Self-assembling nanofibers alter the processing of amyloid precursor protein in a transgenic mouse model of Alzheimer's disease.

Yang H, Yang H, Xie Z, Wang P, Bi J.

Neurol Res. 2015 Jan;37(1):84-91. doi: 10.1179/1743132814Y.0000000417. Epub 2014 Jul 9.

PMID:
25005263
4.

Neuroprotective Effects of Icariin on Brain Metabolism, Mitochondrial Functions, and Cognition in Triple-Transgenic Alzheimer's Disease Mice.

Chen YJ, Zheng HY, Huang XX, Han SX, Zhang DS, Ni JZ, He XY.

CNS Neurosci Ther. 2016 Jan;22(1):63-73. doi: 10.1111/cns.12473. Epub 2015 Nov 20.

PMID:
26584824
5.

Baicalein reduces β-amyloid and promotes nonamyloidogenic amyloid precursor protein processing in an Alzheimer's disease transgenic mouse model.

Zhang SQ, Obregon D, Ehrhart J, Deng J, Tian J, Hou H, Giunta B, Sawmiller D, Tan J.

J Neurosci Res. 2013 Sep;91(9):1239-46. doi: 10.1002/jnr.23244. Epub 2013 May 17.

6.

Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.

Rockenstein E, Torrance M, Mante M, Adame A, Paulino A, Rose JB, Crews L, Moessler H, Masliah E.

J Neurosci Res. 2006 May 15;83(7):1252-61.

PMID:
16511867
7.

MicroRNA-29c targets β-site amyloid precursor protein-cleaving enzyme 1 and has a neuroprotective role in vitro and in vivo.

Yang G, Song Y, Zhou X, Deng Y, Liu T, Weng G, Yu D, Pan S.

Mol Med Rep. 2015 Aug;12(2):3081-8. doi: 10.3892/mmr.2015.3728. Epub 2015 May 5.

PMID:
25955795
8.

Amyloid-beta causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons.

Chiba T, Yamada M, Sasabe J, Terashita K, Shimoda M, Matsuoka M, Aiso S.

Mol Psychiatry. 2009 Feb;14(2):206-22. doi: 10.1038/mp.2008.105. Epub 2008 Sep 23.

PMID:
18813209
9.

L-3-n-butylphthalide improves cognitive impairment and reduces amyloid-beta in a transgenic model of Alzheimer's disease.

Peng Y, Sun J, Hon S, Nylander AN, Xia W, Feng Y, Wang X, Lemere CA.

J Neurosci. 2010 Jun 16;30(24):8180-9. doi: 10.1523/JNEUROSCI.0340-10.2010.

10.

Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease.

Sanchez-Mejia RO, Newman JW, Toh S, Yu GQ, Zhou Y, Halabisky B, Cissé M, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L.

Nat Neurosci. 2008 Nov;11(11):1311-8. doi: 10.1038/nn.2213. Epub 2008 Oct 19.

11.

[Research on EGCG improving the degenerative changes of the brain in AD model mice induced with chemical drugs].

He M, Liu MY, Wang S, Tang QS, Yao WF, Zhao HS, Wei MJ.

Zhong Yao Cai. 2012 Oct;35(10):1641-4. Chinese.

PMID:
23627134
12.

Caffeine suppresses amyloid-beta levels in plasma and brain of Alzheimer's disease transgenic mice.

Cao C, Cirrito JR, Lin X, Wang L, Verges DK, Dickson A, Mamcarz M, Zhang C, Mori T, Arendash GW, Holtzman DM, Potter H.

J Alzheimers Dis. 2009;17(3):681-97. doi: 10.3233/JAD-2009-1071. Erratum in: J Alzheimers Dis. 2009 Nov;18(3):727. Wang, Lilly [corrected to Wang, Li]..

13.

FGF2 gene transfer restores hippocampal functions in mouse models of Alzheimer's disease and has therapeutic implications for neurocognitive disorders.

Kiyota T, Ingraham KL, Jacobsen MT, Xiong H, Ikezu T.

Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):E1339-48. doi: 10.1073/pnas.1102349108. Epub 2011 Oct 31. Erratum in: Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21282.

14.

Novel therapeutic strategy for neurodegeneration by blocking Aβ seeding mediated aggregation in models of Alzheimer's disease.

Eleuteri S, Di Giovanni S, Rockenstein E, Mante M, Adame A, Trejo M, Wrasidlo W, Wu F, Fraering PC, Masliah E, Lashuel HA.

Neurobiol Dis. 2015 Feb;74:144-57. doi: 10.1016/j.nbd.2014.08.017. Epub 2014 Aug 28.

15.

Impaired β-amyloid secretion in Alzheimer's disease pathogenesis.

Tampellini D, Rahman N, Lin MT, Capetillo-Zarate E, Gouras GK.

J Neurosci. 2011 Oct 26;31(43):15384-90. doi: 10.1523/JNEUROSCI.2986-11.2011.

16.

Glucocorticoids increase impairments in learning and memory due to elevated amyloid precursor protein expression and neuronal apoptosis in 12-month old mice.

Li WZ, Li WP, Yao YY, Zhang W, Yin YY, Wu GC, Gong HL.

Eur J Pharmacol. 2010 Feb 25;628(1-3):108-15. doi: 10.1016/j.ejphar.2009.11.045. Epub 2009 Dec 2.

PMID:
19948164
17.

Recombinant soluble neprilysin reduces amyloid-beta accumulation and improves memory impairment in Alzheimer's disease mice.

Park MH, Lee JK, Choi S, Ahn J, Jin HK, Park JS, Bae JS.

Brain Res. 2013 Sep 5;1529:113-24. doi: 10.1016/j.brainres.2013.05.045. Epub 2013 Jul 2.

PMID:
23831521
18.

Impacts of aging and amyloid-β deposition on plasminogen activators and plasminogen activator inhibitor-1 in the Tg2576 mouse model of Alzheimer's disease.

Bi Oh S, Suh N, Kim I, Lee JY.

Brain Res. 2015 Feb 9;1597:159-67. doi: 10.1016/j.brainres.2014.11.042. Epub 2014 Nov 29.

PMID:
25454795
19.

Beneficial effects of a neurotrophic peptidergic mixture persist for a prolonged period following treatment interruption in a transgenic model of Alzheimer's disease.

Rockenstein E, Ubhi K, Pham E, Michael S, Doppler E, Novak P, Inglis C, Mante M, Adame A, Alvarez XA, Moessler H, Masliah E.

J Neurosci Res. 2011 Nov;89(11):1812-21. doi: 10.1002/jnr.22712. Epub 2011 Jul 25.

20.

Intranasal deferoxamine reverses iron-induced memory deficits and inhibits amyloidogenic APP processing in a transgenic mouse model of Alzheimer's disease.

Guo C, Wang T, Zheng W, Shan ZY, Teng WP, Wang ZY.

Neurobiol Aging. 2013 Feb;34(2):562-75. doi: 10.1016/j.neurobiolaging.2012.05.009. Epub 2012 Jun 19.

PMID:
22717236

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