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PDCD2 functions in cancer cell proliferation and predicts relapsed leukemia.

Barboza N, Minakhina S, Medina DJ, Balsara B, Greenwood S, Huzzy L, Rabson AB, Steward R, Schaar DG.

Cancer Biol Ther. 2013 Jun;14(6):546-55. doi: 10.4161/cbt.24484.


PDCD2 controls hematopoietic stem cell differentiation during development.

Kramer J, Granier CJ, Davis S, Piso K, Hand J, Rabson AB, Sabaawy HE.

Stem Cells Dev. 2013 Jan 1;22(1):58-72. doi: 10.1089/scd.2012.0074. Epub 2012 Aug 16.


Zfrp8, the Drosophila ortholog of PDCD2, functions in lymph gland development and controls cell proliferation.

Minakhina S, Druzhinina M, Steward R.

Development. 2007 Jul;134(13):2387-96. Epub 2007 May 23.


Zfrp8/PDCD2 Interacts with RpS2 Connecting Ribosome Maturation and Gene-Specific Translation.

Minakhina S, Naryshkina T, Changela N, Tan W, Steward R.

PLoS One. 2016 Jan 25;11(1):e0147631. doi: 10.1371/journal.pone.0147631. eCollection 2016.


PDCD2 is essential for inner cell mass development and embryonic stem cell maintenance.

Mu W, Munroe RJ, Barker AK, Schimenti JC.

Dev Biol. 2010 Nov 15;347(2):279-88. doi: 10.1016/j.ydbio.2010.08.026. Epub 2010 Sep 9.


Overexpression of the PDCD2-like gene results in inhibited TNF-alpha production in activated Daudi cells.

Chen Q, Yan CQ, Liu FJ, Tong J, Miao SL, Chen JP.

Hum Immunol. 2008 Apr-May;69(4-5):259-65. doi: 10.1016/j.humimm.2008.01.020. Epub 2008 Apr 16.


Hematopoietic stem cells in Drosophila.

Minakhina S, Steward R.

Development. 2010 Jan;137(1):27-31. doi: 10.1242/dev.043943.


Kruppel-like factor 7 overexpression suppresses hematopoietic stem and progenitor cell function.

Schuettpelz LG, Gopalan PK, Giuste FO, Romine MP, van Os R, Link DC.

Blood. 2012 Oct 11;120(15):2981-9. doi: 10.1182/blood-2012-02-409839. Epub 2012 Aug 30.


Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia.

Kharas MG, Lengner CJ, Al-Shahrour F, Bullinger L, Ball B, Zaidi S, Morgan K, Tam W, Paktinat M, Okabe R, Gozo M, Einhorn W, Lane SW, Scholl C, Fröhling S, Fleming M, Ebert BL, Gilliland DG, Jaenisch R, Daley GQ.

Nat Med. 2010 Aug;16(8):903-8. doi: 10.1038/nm.2187. Epub 2010 Jul 8.


Cloning of cDNAs with PDCD2(C) domain and their expressions during apoptosis of HEK293T cells.

Chen Q, Qian K, Yan C.

Mol Cell Biochem. 2005 Dec;280(1-2):185-91.


shRNA-Mediated BAALC knockdown affects proliferation and apoptosis in human acute myeloid leukemia cells.

Xu B, Chen G, Shi P, Guo X, Xiao P, Wang W, Zhou S.

Hematology. 2012 Jan;17(1):35-40. doi: 10.1179/102453312X13221316477499.


miR-129-1-3p promote BGC-823 cell proliferation by targeting PDCD2.

Du Y, Wang D, Luo L, Guo J.

Anat Rec (Hoboken). 2014 Dec;297(12):2273-9. doi: 10.1002/ar.23003. Epub 2014 Aug 11.


Mesenchymal stromal cells from patients with acute myeloid leukemia have altered capacity to expand differentiated hematopoietic progenitors.

Chandran P, Le Y, Li Y, Sabloff M, Mehic J, Rosu-Myles M, Allan DS.

Leuk Res. 2015 Apr;39(4):486-93. doi: 10.1016/j.leukres.2015.01.013. Epub 2015 Feb 2.


Conserved alternative and antisense transcripts at the programmed cell death 2 locus.

Mihola O, Forejt J, Trachtulec Z.

BMC Genomics. 2007 Jan 18;8:20.


PDCD2, a protein whose expression is repressed by BCL6, induces apoptosis in human cells by activation of the caspase cascade.

Baron BW, Hyjek E, Gladstone B, Thirman MJ, Baron JM.

Blood Cells Mol Dis. 2010 Aug 15;45(2):169-75. doi: 10.1016/j.bcmd.2010.04.007. Epub 2010 Jun 3.


Programmed cell death 2 protein induces gastric cancer cell growth arrest at the early S phase of the cell cycle and apoptosis in a p53-dependent manner.

Zhang J, Wei W, Jin HC, Ying RC, Zhu AK, Zhang FJ.

Oncol Rep. 2015 Jan;33(1):103-10. doi: 10.3892/or.2014.3551. Epub 2014 Oct 17.


Repression of the PDCD2 gene by BCL6 and the implications for the pathogenesis of human B and T cell lymphomas.

Baron BW, Zeleznik-Le N, Baron MJ, Theisler C, Huo D, Krasowski MD, Thirman MJ, Baron RM, Baron JM.

Proc Natl Acad Sci U S A. 2007 May 1;104(18):7449-54. Epub 2007 Apr 27.


Transcription factor AP-2α regulates acute myeloid leukemia cell proliferation by influencing Hoxa gene expression.

Ding X, Yang Z, Zhou F, Wang F, Li X, Chen C, Li X, Hu X, Xiang S, Zhang J.

Int J Biochem Cell Biol. 2013 Aug;45(8):1647-56. doi: 10.1016/j.biocel.2013.04.024. Epub 2013 May 6.


The transcription factor PlagL2 activates Mpl transcription and signaling in hematopoietic progenitor and leukemia cells.

Landrette SF, Madera D, He F, Castilla LH.

Leukemia. 2011 Apr;25(4):655-62. doi: 10.1038/leu.2010.301. Epub 2011 Jan 25.


Differential expression of the novel oncogene, SALL4, in lymphoma, plasma cell myeloma, and acute lymphoblastic leukemia.

Cui W, Kong NR, Ma Y, Amin HM, Lai R, Chai L.

Mod Pathol. 2006 Dec;19(12):1585-92. Epub 2006 Sep 22.

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