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Items: 1 to 20 of 125

1.

Ubiquitination of tumor necrosis factor receptor-associated factor 4 (TRAF4) by Smad ubiquitination regulatory factor 1 (Smurf1) regulates motility of breast epithelial and cancer cells.

Wang X, Jin C, Tang Y, Tang LY, Zhang YE.

J Biol Chem. 2013 Jul 26;288(30):21784-92. doi: 10.1074/jbc.M113.472704. Epub 2013 Jun 11.

2.

Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation.

Li S, Lu K, Wang J, An L, Yang G, Chen H, Cui Y, Yin X, Xie P, Xing G, He F, Zhang L.

Mol Cell Biochem. 2010 May;338(1-2):11-7. doi: 10.1007/s11010-009-0315-y. Epub 2009 Nov 24.

PMID:
19937093
3.

TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.

Zhang L, Zhou F, García de Vinuesa A, de Kruijf EM, Mesker WE, Hui L, Drabsch Y, Li Y, Bauer A, Rousseau A, Sheppard KA, Mickanin C, Kuppen PJ, Lu CX, Ten Dijke P.

Mol Cell. 2013 Sep 12;51(5):559-72. doi: 10.1016/j.molcel.2013.07.014. Epub 2013 Aug 22.

4.

Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.

Xie Y, Avello M, Schirle M, McWhinnie E, Feng Y, Bric-Furlong E, Wilson C, Nathans R, Zhang J, Kirschner MW, Huang SM, Cong F.

J Biol Chem. 2013 Feb 1;288(5):2976-85. doi: 10.1074/jbc.M112.430066. Epub 2012 Nov 26.

5.

Tumor necrosis factor-receptor-associated factor-4 is a positive regulator of transforming growth factor-beta signaling that affects neural crest formation.

Kalkan T, Iwasaki Y, Park CY, Thomsen GH.

Mol Biol Cell. 2009 Jul;20(14):3436-50. doi: 10.1091/mbc.E08-03-0325. Epub 2009 May 20.

6.

Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells.

Fukunaga E, Inoue Y, Komiya S, Horiguchi K, Goto K, Saitoh M, Miyazawa K, Koinuma D, Hanyu A, Imamura T.

J Biol Chem. 2008 Dec 19;283(51):35660-7. doi: 10.1074/jbc.M710496200. Epub 2008 Oct 16.

7.

SMURF1 plays a role in EGF-induced breast cancer cell migration and invasion.

Kwon A, Lee HL, Woo KM, Ryoo HM, Baek JH.

Mol Cells. 2013 Dec;36(6):548-55. doi: 10.1007/s10059-013-0233-4. Epub 2013 Nov 14.

8.

TRAF2 regulates the cytoplasmic/nuclear distribution of TRAF4 and its biological function in breast cancer cells.

Zhang X, Wen Z, Sun L, Wang J, Song M, Wang E, Mi X.

Biochem Biophys Res Commun. 2013 Jun 28;436(2):344-8. doi: 10.1016/j.bbrc.2013.05.107. Epub 2013 Jun 4.

PMID:
23743189
9.

SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization.

Yi P, Xia W, Wu RC, Lonard DM, Hung MC, O'Malley BW.

Genes Dev. 2013 Feb 1;27(3):274-87. doi: 10.1101/gad.203760.112.

10.

Smurf1-mediated Lys29-linked nonproteolytic polyubiquitination of axin negatively regulates Wnt/β-catenin signaling.

Fei C, Li Z, Li C, Chen Y, Chen Z, He X, Mao L, Wang X, Zeng R, Li L.

Mol Cell Biol. 2013 Oct;33(20):4095-105. doi: 10.1128/MCB.00418-13. Epub 2013 Aug 19.

11.

TRAF4 promotes tumorigenesis of breast cancer through activation of Akt.

Zhang J, Li X, Yang W, Jiang X, Li N.

Oncol Rep. 2014 Sep;32(3):1312-8. doi: 10.3892/or.2014.3304. Epub 2014 Jul 3.

PMID:
24993240
12.

Smurf1 ubiquitin ligase targets Kruppel-like factor KLF2 for ubiquitination and degradation in human lung cancer H1299 cells.

Xie P, Tang Y, Shen S, Wang Y, Xing G, Yin Y, He F, Zhang L.

Biochem Biophys Res Commun. 2011 Apr 1;407(1):254-9. doi: 10.1016/j.bbrc.2011.03.016. Epub 2011 Mar 5.

PMID:
21382345
13.

Tumor necrosis factor receptor-associated factor 4 is a dynamic tight junction-related shuttle protein involved in epithelium homeostasis.

Kédinger V, Alpy F, Baguet A, Polette M, Stoll I, Chenard MP, Tomasetto C, Rio MC.

PLoS One. 2008;3(10):e3518. doi: 10.1371/journal.pone.0003518. Epub 2008 Oct 27. Erratum in: PLoS ONE. 2008;3(11). doi: 10.1371/annotation/2019a487-1af6-4f4e-882a-16398799e882.

14.

TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration.

Rousseau A, McEwen AG, Poussin-Courmontagne P, Rognan D, Nominé Y, Rio MC, Tomasetto C, Alpy F.

PLoS Biol. 2013 Dec;11(12):e1001726. doi: 10.1371/journal.pbio.1001726. Epub 2013 Dec 3.

15.

Tumor necrosis factor-α enhances the transcription of Smad ubiquitination regulatory factor 1 in an activating protein-1- and Runx2-dependent manner.

Lee HL, Yi T, Baek K, Kwon A, Hwang HR, Qadir AS, Park HJ, Woo KM, Ryoo HM, Kim GS, Baek JH.

J Cell Physiol. 2013 May;228(5):1076-86. doi: 10.1002/jcp.24256.

PMID:
23042144
16.

Smurf1 represses TNF-α production through ubiquitination and destabilization of USP5.

Qian G, Ren Y, Zuo Y, Yuan Y, Zhao P, Wang X, Cheng Q, Liu J, Zhang L, Guo T, Liu C, Zheng H.

Biochem Biophys Res Commun. 2016 Jun 3;474(3):491-496. doi: 10.1016/j.bbrc.2016.04.135. Epub 2016 Apr 29.

PMID:
27133717
17.

Autoubiquitination of BCA2 RING E3 ligase regulates its own stability and affects cell migration.

Amemiya Y, Azmi P, Seth A.

Mol Cancer Res. 2008 Sep;6(9):1385-96. doi: 10.1158/1541-7786.MCR-08-0094.

18.

Smurf1 controls S phase progression and tumorigenesis through Wee1 degradation.

Wei R, Guo J, Li M, Yang X, Zhu R, Huang H, Li K, Zhang L, Gao R.

FEBS Lett. 2017 Apr;591(8):1150-1158. doi: 10.1002/1873-3468.12624. Epub 2017 Apr 3.

PMID:
28294307
19.

Smad ubiquitylation regulatory factor 1/2 (Smurf1/2) promotes p53 degradation by stabilizing the E3 ligase MDM2.

Nie J, Xie P, Liu L, Xing G, Chang Z, Yin Y, Tian C, He F, Zhang L.

J Biol Chem. 2010 Jul 23;285(30):22818-30. doi: 10.1074/jbc.M110.126920. Epub 2010 May 18.

20.

SCF E3 ligase F-box protein complex SCF(FBXL19) regulates cell migration by mediating Rac1 ubiquitination and degradation.

Zhao J, Mialki RK, Wei J, Coon TA, Zou C, Chen BB, Mallampalli RK, Zhao Y.

FASEB J. 2013 Jul;27(7):2611-9. doi: 10.1096/fj.12-223099. Epub 2013 Mar 19.

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