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Items: 1 to 20 of 724

1.

Phenethyl isothiocyanate triggers apoptosis in human malignant melanoma A375.S2 cells through reactive oxygen species and the mitochondria-dependent pathways.

Huang SH, Hsu MH, Hsu SC, Yang JS, Huang WW, Huang AC, Hsiao YP, Yu CC, Chung JG.

Hum Exp Toxicol. 2014 Mar;33(3):270-83. doi: 10.1177/0960327113491508. Epub 2013 Jun 11.

PMID:
23760257
2.

Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.

Huang SH, Wu LW, Huang AC, Yu CC, Lien JC, Huang YP, Yang JS, Yang JH, Hsiao YP, Wood WG, Yu CS, Chung JG.

J Agric Food Chem. 2012 Jan 18;60(2):665-75. doi: 10.1021/jf204193v. Epub 2012 Jan 6.

PMID:
22148415
4.

Phenethyl isothiocyanate (PEITC) promotes G2/M phase arrest via p53 expression and induces apoptosis through caspase- and mitochondria-dependent signaling pathways in human prostate cancer DU 145 cells.

Tang NY, Huang YT, Yu CS, Ko YC, Wu SH, Ji BC, Yang JS, Yang JL, Hsia TC, Chen YY, Chung JG.

Anticancer Res. 2011 May;31(5):1691-702.

PMID:
21617228
5.

Phenethyl isothiocyanate induces DNA damage-associated G2/M arrest and subsequent apoptosis in oral cancer cells with varying p53 mutations.

Yeh YT, Yeh H, Su SH, Lin JS, Lee KJ, Shyu HW, Chen ZF, Huang SY, Su SJ.

Free Radic Biol Med. 2014 Sep;74:1-13. doi: 10.1016/j.freeradbiomed.2014.06.008. Epub 2014 Jun 19.

PMID:
24952138
6.

Triptolide induces S phase arrest via the inhibition of cyclin E and CDC25A and triggers apoptosis via caspase- and mitochondrial-dependent signaling pathways in A375.S2 human melanoma cells.

Hung FM, Chen YL, Huang AC, Hsiao YP, Yang JS, Chung MT, Chueh FS, Lu HF, Chung JG.

Oncol Rep. 2013 Mar;29(3):1053-60. doi: 10.3892/or.2013.2230. Epub 2013 Jan 8.

PMID:
23314229
7.

Cantharidin induces G2/M phase arrest by inhibition of Cdc25c and Cyclin A and triggers apoptosis through reactive oxygen species and the mitochondria‑dependent pathways of A375.S2 human melanoma cells.

Hsiao YP, Tsai CH, Wu PP, Hsu SC, Liu HC, Huang YP, Yang JH, Chung JG.

Int J Oncol. 2014 Dec;45(6):2393-402. doi: 10.3892/ijo.2014.2689. Epub 2014 Sep 30.

PMID:
25340978
8.

Gallic acid induces apoptosis in A375.S2 human melanoma cells through caspase-dependent and -independent pathways.

Lo C, Lai TY, Yang JH, Yang JS, Ma YS, Weng SW, Chen YY, Lin JG, Chung JG.

Int J Oncol. 2010 Aug;37(2):377-85.

PMID:
20596665
9.

PEITC induces apoptosis of Human Brain Glioblastoma GBM8401 Cells through the extrinsic- and intrinsic -signaling pathways.

Chou YC, Chang MY, Wang MJ, Harnod T, Hung CH, Lee HT, Shen CC, Chung JG.

Neurochem Int. 2015 Feb;81:32-40. doi: 10.1016/j.neuint.2015.01.001. Epub 2015 Jan 9.

10.

Phenethyl isothiocyanate induced apoptosis via down regulation of Bcl-2/XIAP and triggering of the mitochondrial pathway in MCF-7 cells.

Lee JW, Cho MK.

Arch Pharm Res. 2008 Dec;31(12):1604-12. doi: 10.1007/s12272-001-2158-2. Epub 2008 Dec 20.

PMID:
19099231
12.

Casticin Induced Apoptosis in A375.S2 Human Melanoma Cells through the Inhibition of NF-[Formula: see text]B and Mitochondria-Dependent Pathways In Vitro and Inhibited Human Melanoma Xenografts in a Mouse Model In Vivo.

Shiue YW, Lu CC, Hsiao YP, Liao CL, Lin JP, Lai KC, Yu CC, Huang YP, Ho HC, Chung JG.

Am J Chin Med. 2016;44(3):637-61. doi: 10.1142/S0192415X1650035X. Epub 2016 Apr 24.

PMID:
27109154
13.

Sodium ascorbate inhibits growth via the induction of cell cycle arrest and apoptosis in human malignant melanoma A375.S2 cells.

Lin SY, Lai WW, Chou CC, Kuo HM, Li TM, Chung JG, Yang JH.

Melanoma Res. 2006 Dec;16(6):509-19.

PMID:
17119452
14.

Involvement of reactive oxygen species and caspase-dependent pathway in berberine-induced cell cycle arrest and apoptosis in C6 rat glioma cells.

Chen TC, Lai KC, Yang JS, Liao CL, Hsia TC, Chen GW, Lin JJ, Lin HJ, Chiu TH, Tang YJ, Chung JG.

Int J Oncol. 2009 Jun;34(6):1681-90.

PMID:
19424587
15.

Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells.

Wang CC, Chiang YM, Sung SC, Hsu YL, Chang JK, Kuo PL.

Cancer Lett. 2008 Jan 18;259(1):82-98. Epub 2007 Nov 19.

PMID:
18023967
17.

Danthron, an anthraquinone derivative, induces DNA damage and caspase cascades-mediated apoptosis in SNU-1 human gastric cancer cells through mitochondrial permeability transition pores and Bax-triggered pathways.

Chiang JH, Yang JS, Ma CY, Yang MD, Huang HY, Hsia TC, Kuo HM, Wu PP, Lee TH, Chung JG.

Chem Res Toxicol. 2011 Jan 14;24(1):20-9. doi: 10.1021/tx100248s. Epub 2010 Dec 2.

PMID:
21126053
18.

Mitochondrial-dependent caspase activation pathway is involved in baicalein-induced apoptosis in human hepatoma J5 cells.

Kuo HM, Tsai HC, Lin YL, Yang JS, Huang AC, Yang MD, Hsu SC, Chung MC, Gibson Wood W, Chung JG.

Int J Oncol. 2009 Oct;35(4):717-24.

PMID:
19724907
19.

Beta-phenylethyl isothiocyanate mediated apoptosis; contribution of Bax and the mitochondrial death pathway.

Rose P, Armstrong JS, Chua YL, Ong CN, Whiteman M.

Int J Biochem Cell Biol. 2005 Jan;37(1):100-19.

PMID:
15381154
20.

Phenethyl isothiocyanate-induced apoptosis in PC-3 human prostate cancer cells is mediated by reactive oxygen species-dependent disruption of the mitochondrial membrane potential.

Xiao D, Lew KL, Zeng Y, Xiao H, Marynowski SW, Dhir R, Singh SV.

Carcinogenesis. 2006 Nov;27(11):2223-34. Epub 2006 Jun 13.

PMID:
16774948

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