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Items: 1 to 20 of 99


Random fluctuation of selection coefficients and the extent of nucleotide variation in human populations.

Miura S, Zhang Z, Nei M.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10676-81. doi: 10.1073/pnas.1308462110. Epub 2013 Jun 10.


Relative effects of mutability and selection on single nucleotide polymorphisms in transcribed regions of the human genome.

Gorlov IP, Gorlova OY, Amos CI.

BMC Genomics. 2008 Jun 17;9:292. doi: 10.1186/1471-2164-9-292.


The evolution of isochores: evidence from SNP frequency distributions.

Lercher MJ, Smith NG, Eyre-Walker A, Hurst LD.

Genetics. 2002 Dec;162(4):1805-10.


Empirical distributions of F(ST) from large-scale human polymorphism data.

Elhaik E.

PLoS One. 2012;7(11):e49837. doi: 10.1371/journal.pone.0049837. Epub 2012 Nov 21.


Interrogating a high-density SNP map for signatures of natural selection.

Akey JM, Zhang G, Zhang K, Jin L, Shriver MD.

Genome Res. 2002 Dec;12(12):1805-14.


Fluctuating Selection in the Moran.

Dean AM, Lehman C, Yi X.

Genetics. 2017 Mar;205(3):1271-1283. doi: 10.1534/genetics.116.192914. Epub 2017 Jan 20.


A simple method for analyzing exome sequencing data shows distinct levels of nonsynonymous variation for human immune and nervous system genes.

Freudenberg J, Gregersen PK, Freudenberg-Hua Y.

PLoS One. 2012;7(6):e38087. doi: 10.1371/journal.pone.0038087. Epub 2012 Jun 6.


Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution.

Ling S, Hu Z, Yang Z, Yang F, Li Y, Lin P, Chen K, Dong L, Cao L, Tao Y, Hao L, Chen Q, Gong Q, Wu D, Li W, Zhao W, Tian X, Hao C, Hungate EA, Catenacci DV, Hudson RR, Li WH, Lu X, Wu CI.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6496-505. doi: 10.1073/pnas.1519556112. Epub 2015 Nov 11. Erratum in: Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E663.


Simulating sequences of the human genome with rare variants.

Peng B, Liu X.

Hum Hered. 2010;70(4):287-91. doi: 10.1159/000323316. Epub 2011 Jan 6.


Geographical distribution of selected and putatively neutral SNPs in Southeast Asian malaria parasites.

Anderson TJ, Nair S, Sudimack D, Williams JT, Mayxay M, Newton PN, Guthmann JP, Smithuis FM, Tran TH, van den Broek IV, White NJ, Nosten F.

Mol Biol Evol. 2005 Dec;22(12):2362-74. Epub 2005 Aug 10.


Variable SNP density in aspartyl-protease genes of the malaria parasite Plasmodium falciparum.

Barry AE, Leliwa-Sytek A, Man K, Kasper JM, Hartl DL, Day KP.

Gene. 2006 Jul 19;376(2):163-73. Epub 2006 Apr 5.


Inference of purifying and positive selection in three subspecies of chimpanzees (Pan troglodytes) from exome sequencing.

Bataillon T, Duan J, Hvilsom C, Jin X, Li Y, Skov L, Glemin S, Munch K, Jiang T, Qian Y, Hobolth A, Wang J, Mailund T, Siegismund HR, Schierup MH.

Genome Biol Evol. 2015 Mar 30;7(4):1122-32. doi: 10.1093/gbe/evv058.


The effects of demography and long-term selection on the accuracy of genomic prediction with sequence data.

MacLeod IM, Hayes BJ, Goddard ME.

Genetics. 2014 Dec;198(4):1671-84. doi: 10.1534/genetics.114.168344. Epub 2014 Sep 18.


Positive and negative selection on the human genome.

Fay JC, Wyckoff GJ, Wu CI.

Genetics. 2001 Jul;158(3):1227-34.


DNA sequence variation in a 3.7-kb noncoding sequence 5' of the CYP1A2 gene: implications for human population history and natural selection.

Wooding SP, Watkins WS, Bamshad MJ, Dunn DM, Weiss RB, Jorde LB.

Am J Hum Genet. 2002 Sep;71(3):528-42. Epub 2002 Aug 9.


The molecular nature of allelic diversity for two models of balancing selection.

Gillespie JH.

Theor Popul Biol. 1990 Feb;37(1):91-109.


A whole genome long-range haplotype (WGLRH) test for detecting imprints of positive selection in human populations.

Zhang C, Bailey DK, Awad T, Liu G, Xing G, Cao M, Valmeekam V, Retief J, Matsuzaki H, Taub M, Seielstad M, Kennedy GC.

Bioinformatics. 2006 Sep 1;22(17):2122-8. Epub 2006 Jul 15.


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