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Items: 1 to 20 of 89

1.

UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells.

Brunner R, Ng CL, Aissaoui H, Akabas MH, Boss C, Brun R, Callaghan PS, Corminboeuf O, Fidock DA, Frame IJ, Heidmann B, Le Bihan A, Jenö P, Mattheis C, Moes S, Müller IB, Paguio M, Roepe PD, Siegrist R, Voss T, Welford RW, Wittlin S, Binkert C.

J Biol Chem. 2013 Aug 2;288(31):22576-83. doi: 10.1074/jbc.M113.453159. Epub 2013 Jun 10.

2.

Influence of the Plasmodium falciparum P-glycoprotein homologue 1 (pfmdr1 gene product) on the antimalarial action of cyclosporin.

Gavigan CS, Shen M, Machado SG, Bell A.

J Antimicrob Chemother. 2007 Feb;59(2):197-203. Epub 2006 Nov 13.

PMID:
17105736
3.

Pleiotropic resistance to diverse antimalarials in actinomycin D-resistant Plasmodium falciparum.

Abrahem A, Certad G, Pan X, Georges E.

Biochem Pharmacol. 2000 May 1;59(9):1123-32.

PMID:
10704942
4.

PfMDR1: mechanisms of transport modulation by functional polymorphisms.

Ferreira PE, Holmgren G, Veiga MI, Uhlén P, Kaneko A, Gil JP.

PLoS One. 2011;6(9):e23875. doi: 10.1371/journal.pone.0023875. Epub 2011 Sep 1.

6.

A 2-amino quinoline, 5-(3-(2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid, interacts with PfMDR1 and inhibits its drug transport in Plasmodium falciparum.

Edaye S, Reiling SJ, Leimanis ML, Wunderlich J, Rohrbach P, Georges E.

Mol Biochem Parasitol. 2014 Jun;195(1):34-42. doi: 10.1016/j.molbiopara.2014.05.006. Epub 2014 Jun 8.

PMID:
24914817
7.

Increased prevalence of the Plasmodium falciparum Pfmdr1 86N genotype among field isolates from Franceville, Gabon after replacement of chloroquine by artemether-lumefantrine and artesunate-mefloquine.

Lekana-Douki JB, Dinzouna Boutamba SD, Zatra R, Zang Edou SE, Ekomy H, Bisvigou U, Toure-Ndouo FS.

Infect Genet Evol. 2011 Mar;11(2):512-7. doi: 10.1016/j.meegid.2011.01.003. Epub 2011 Jan 17.

PMID:
21251998
9.

Intrahost selection of Plasmodium falciparum pfmdr1 alleles after antimalarial treatment on the northwestern border of Thailand.

Uhlemann AC, McGready R, Ashley EA, Brockman A, Singhasivanon P, Krishna S, White NJ, Nosten F, Price RN.

J Infect Dis. 2007 Jan 1;195(1):134-41. Epub 2006 Nov 21.

10.
11.

Contribution of the pfmdr1 gene to antimalarial drug-resistance.

Duraisingh MT, Cowman AF.

Acta Trop. 2005 Jun;94(3):181-90. Review.

PMID:
15876420
12.

Surveillance of artemether-lumefantrine associated Plasmodium falciparum multidrug resistance protein-1 gene polymorphisms in Tanzania.

Kavishe RA, Paulo P, Kaaya RD, Kalinga A, van Zwetselaar M, Chilongola J, Roper C, Alifrangis M.

Malar J. 2014 Jul 9;13:264. doi: 10.1186/1475-2875-13-264.

13.

Heterologous expression and ATPase activity of mutant versus wild type PfMDR1 protein.

Amoah LE, Lekostaj JK, Roepe PD.

Biochemistry. 2007 May 22;46(20):6060-73. Epub 2007 May 1.

PMID:
17469853
14.

Pfcrt 76T and pfmdr1 86Y allele frequency in Plasmodium falciparum isolates and use of self-medication in a rural area of Gabon.

Mawili-Mboumba DP, Ndong Ngomo JM, Maboko F, Guiyedi V, Mourou Mbina JR, Kombila M, Bouyou Akotet MK.

Trans R Soc Trop Med Hyg. 2014 Nov;108(11):729-34. doi: 10.1093/trstmh/tru147. Epub 2014 Sep 23.

PMID:
25249358
15.

Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum.

Reed MB, Saliba KJ, Caruana SR, Kirk K, Cowman AF.

Nature. 2000 Feb 24;403(6772):906-9.

PMID:
10706290
16.

Role of Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes on in vitro chloroquine resistance in isolates of Plasmodium falciparum from Thailand.

Setthaudom C, Tan-ariya P, Sitthichot N, Khositnithikul R, Suwandittakul N, Leelayoova S, Mungthin M.

Am J Trop Med Hyg. 2011 Oct;85(4):606-11. doi: 10.4269/ajtmh.2011.11-0108.

17.

The pfmdr1 gene is associated with a multidrug-resistant phenotype in Plasmodium falciparum from the western border of Thailand.

Price RN, Cassar C, Brockman A, Duraisingh M, van Vugt M, White NJ, Nosten F, Krishna S.

Antimicrob Agents Chemother. 1999 Dec;43(12):2943-9.

18.

Discordant patterns of genetic variation at two chloroquine resistance loci in worldwide populations of the malaria parasite Plasmodium falciparum.

Mehlotra RK, Mattera G, Bockarie MJ, Maguire JD, Baird JK, Sharma YD, Alifrangis M, Dorsey G, Rosenthal PJ, Fryauff DJ, Kazura JW, Stoneking M, Zimmerman PA.

Antimicrob Agents Chemother. 2008 Jun;52(6):2212-22. doi: 10.1128/AAC.00089-08. Epub 2008 Apr 14.

19.

Assessing the cost-benefit effect of a Plasmodium falciparum drug resistance mutation on parasite growth in vitro.

Fröberg G, Ferreira PE, Mårtensson A, Ali A, Björkman A, Gil JP.

Antimicrob Agents Chemother. 2013 Feb;57(2):887-92. doi: 10.1128/AAC.00950-12. Epub 2012 Dec 3.

20.

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