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Items: 1 to 20 of 132

1.

Heterozygous disruption of renal outer medullary potassium channel in rats is associated with reduced blood pressure.

Zhou X, Zhang Z, Shin MK, Horwitz SB, Levorse JM, Zhu L, Sharif-Rodriguez W, Streltsov DY, Dajee M, Hernandez M, Pan Y, Urosevic-Price O, Wang L, Forrest G, Szeto D, Zhu Y, Cui Y, Michael B, Balogh LA, Welling PA, Wade JB, Roy S, Sullivan KA.

Hypertension. 2013 Aug;62(2):288-94. doi: 10.1161/HYPERTENSIONAHA.111.01051. Epub 2013 Jun 10.

2.

Elevated BSC-1 and ROMK expression in Dahl salt-sensitive rat kidneys.

Hoagland KM, Flasch AK, Dahly-Vernon AJ, dos Santos EA, Knepper MA, Roman RJ.

Hypertension. 2004 Apr;43(4):860-5. Epub 2004 Feb 16.

3.

Renal outer medullary potassium channel knockout models reveal thick ascending limb function and dysfunction.

Wang T.

Clin Exp Nephrol. 2012 Feb;16(1):49-54. doi: 10.1007/s10157-011-0495-0. Epub 2011 Nov 1. Review.

PMID:
22038261
4.

Mouse model of type II Bartter's syndrome. II. Altered expression of renal sodium- and water-transporting proteins.

Wagner CA, Loffing-Cueni D, Yan Q, Schulz N, Fakitsas P, Carrel M, Wang T, Verrey F, Geibel JP, Giebisch G, Hebert SC, Loffing J.

Am J Physiol Renal Physiol. 2008 Jun;294(6):F1373-80. doi: 10.1152/ajprenal.00613.2007. Epub 2008 Mar 5.

5.

Chronic Inhibition of Renal Outer Medullary Potassium Channel Not Only Prevented but Also Reversed Development of Hypertension and End-Organ Damage in Dahl Salt-Sensitive Rats.

Zhou X, Forrest MJ, Sharif-Rodriguez W, Forrest G, Szeto D, Urosevic-Price O, Zhu Y, Stevenson AS, Zhou Y, Stribling S, Dajee M, Walsh SP, Pasternak A, Sullivan KA.

Hypertension. 2017 Feb;69(2):332-338. doi: 10.1161/HYPERTENSIONAHA.116.08358. Epub 2016 Dec 5.

PMID:
27920129
6.

Absence of small conductance K+ channel (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in ROMK (Bartter's) knockout mice.

Lu M, Wang T, Yan Q, Yang X, Dong K, Knepper MA, Wang W, Giebisch G, Shull GE, Hebert SC.

J Biol Chem. 2002 Oct 4;277(40):37881-7. Epub 2002 Jul 18.

7.

Mouse model of type II Bartter's syndrome. I. Upregulation of thiazide-sensitive Na-Cl cotransport activity.

Cantone A, Yang X, Yan Q, Giebisch G, Hebert SC, Wang T.

Am J Physiol Renal Physiol. 2008 Jun;294(6):F1366-72. doi: 10.1152/ajprenal.00608.2007. Epub 2008 Apr 2.

8.

Maxi-K channels contribute to urinary potassium excretion in the ROMK-deficient mouse model of Type II Bartter's syndrome and in adaptation to a high-K diet.

Bailey MA, Cantone A, Yan Q, MacGregor GG, Leng Q, Amorim JB, Wang T, Hebert SC, Giebisch G, Malnic G.

Kidney Int. 2006 Jul;70(1):51-9. Epub 2006 May 17.

9.

Romk1 Knockout Mice Do Not Produce Bartter Phenotype but Exhibit Impaired K Excretion.

Dong K, Yan Q, Lu M, Wan L, Hu H, Guo J, Boulpaep E, Wang W, Giebisch G, Hebert SC, Wang T.

J Biol Chem. 2016 Mar 4;291(10):5259-69. doi: 10.1074/jbc.M115.707877. Epub 2016 Jan 4.

10.

Pharmacologic inhibition of the renal outer medullary potassium channel causes diuresis and natriuresis in the absence of kaliuresis.

Garcia ML, Priest BT, Alonso-Galicia M, Zhou X, Felix JP, Brochu RM, Bailey T, Thomas-Fowlkes B, Liu J, Swensen A, Pai LY, Xiao J, Hernandez M, Hoagland K, Owens K, Tang H, de Jesus RK, Roy S, Kaczorowski GJ, Pasternak A.

J Pharmacol Exp Ther. 2014 Jan;348(1):153-64. doi: 10.1124/jpet.113.208603. Epub 2013 Oct 18.

12.

Altered renal expression of Na(+) transporters and ROMK in protein-deprived rats.

Ruete MC, Carrizo LC, Bocanegra MV, Vallés PG.

Nephron Physiol. 2009;111(3):p17-29. doi: 10.1159/000199462. Epub 2009 Feb 6.

PMID:
19202345
13.

ROMK is required for expression of the 70-pS K channel in the thick ascending limb.

Lu M, Wang T, Yan Q, Wang W, Giebisch G, Hebert SC.

Am J Physiol Renal Physiol. 2004 Mar;286(3):F490-5. Epub 2003 Nov 4.

14.

Hyperphosphorylation of Na-K-2Cl cotransporter in thick ascending limbs of Dahl salt-sensitive rats.

Ares GR, Haque MZ, Delpire E, Ortiz PA.

Hypertension. 2012 Dec;60(6):1464-70. doi: 10.1161/HYPERTENSIONAHA.112.202101. Epub 2012 Oct 29.

15.

Potassium restriction downregulates ROMK expression in rat kidney.

Mennitt PA, Frindt G, Silver RB, Palmer LG.

Am J Physiol Renal Physiol. 2000 Jun;278(6):F916-24.

16.

Genetic heterogeneity of Bartter's syndrome revealed by mutations in the K+ channel, ROMK.

Simon DB, Karet FE, Rodriguez-Soriano J, Hamdan JH, DiPietro A, Trachtman H, Sanjad SA, Lifton RP.

Nat Genet. 1996 Oct;14(2):152-6.

PMID:
8841184
18.

Differential gene regulation of renal salt entry pathways by salt load in the distal nephron of the rat.

Wolf K, Castrop H, Riegger GA, Kurtz A, Krämer BK.

Pflugers Arch. 2001 Jul;442(4):498-504.

PMID:
11510880
19.

Rare independent mutations in renal salt handling genes contribute to blood pressure variation.

Ji W, Foo JN, O'Roak BJ, Zhao H, Larson MG, Simon DB, Newton-Cheh C, State MW, Levy D, Lifton RP.

Nat Genet. 2008 May;40(5):592-9. doi: 10.1038/ng.118. Epub 2008 Apr 6.

20.

Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension.

Ronzaud C, Loffing-Cueni D, Hausel P, Debonneville A, Malsure SR, Fowler-Jaeger N, Boase NA, Perrier R, Maillard M, Yang B, Stokes JB, Koesters R, Kumar S, Hummler E, Loffing J, Staub O.

J Clin Invest. 2013 Feb;123(2):657-65. doi: 10.1172/JCI61110. Epub 2013 Jan 25.

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