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Items: 1 to 20 of 97

1.

Role of macrophage-derived hypoxia-inducible factor (HIF)-1α as a mediator of vascular remodelling.

Nakayama T, Kurobe H, Sugasawa N, Kinoshita H, Higashida M, Matsuoka Y, Yoshida Y, Hirata Y, Sakata M, Maxfield MW, Shimabukuro M, Takahama Y, Sata M, Tamaki T, Kitagawa T, Tomita S.

Cardiovasc Res. 2013 Sep 1;99(4):705-15. doi: 10.1093/cvr/cvt146. Epub 2013 Jun 10.

PMID:
23752975
2.

Smooth muscle cell-specific Hif-1α deficiency suppresses angiotensin II-induced vascular remodelling in mice.

Imanishi M, Tomita S, Ishizawa K, Kihira Y, Ueno M, Izawa-Ishizawa Y, Ikeda Y, Yamano N, Tsuchiya K, Tamaki T.

Cardiovasc Res. 2014 Jun 1;102(3):460-8. doi: 10.1093/cvr/cvu061. Epub 2014 Mar 12.

PMID:
24623277
3.

Knockout of HIF-1α in tumor-associated macrophages enhances M2 polarization and attenuates their pro-angiogenic responses.

Werno C, Menrad H, Weigert A, Dehne N, Goerdt S, Schledzewski K, Kzhyshkowska J, Brüne B.

Carcinogenesis. 2010 Oct;31(10):1863-72. doi: 10.1093/carcin/bgq088. Epub 2010 Apr 28.

PMID:
20427344
4.

Role of hypoxia-inducible factor 1alpha in T cells as a negative regulator in development of vascular remodeling.

Kurobe H, Urata M, Ueno M, Ueki M, Ono S, Izawa-Ishizawa Y, Fukuhara Y, Lei Y, Ripen AM, Kanbara T, Aihara K, Ishizawa K, Akaike M, Gonzalez FJ, Tamaki T, Takahama Y, Yoshizumi M, Kitagawa T, Tomita S.

Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):210-7. doi: 10.1161/ATVBAHA.109.192666. Epub 2009 Dec 10.

5.

Hypoxia-Inducible Factor 1α Is a Critical Downstream Mediator for Hypoxia-Induced Mitogenic Factor (FIZZ1/RELMα)-Induced Pulmonary Hypertension.

Johns RA, Takimoto E, Meuchel LW, Elsaigh E, Zhang A, Heller NM, Semenza GL, Yamaji-Kegan K.

Arterioscler Thromb Vasc Biol. 2016 Jan;36(1):134-44. doi: 10.1161/ATVBAHA.115.306710. Epub 2015 Nov 19.

6.

Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery:inflammatory responses of hypoxia-inducible factor 1α (HIF-1α) in T cells observed in development of vascular remodeling.

Tomita S, Kihira Y, Imanishi M, Fukuhara Y, Imamura Y, Ishizawa K, Ikeda Y, Tsuchiya K, Tamaki T.

J Pharmacol Sci. 2011;115(4):433-9. Epub 2011 Mar 16. Review.

7.

Evaluation of hypoxia inducible factor expression in inflammatory and neurodegenerative brain models.

de Lemos ML, de la Torre AV, Petrov D, Brox S, Folch J, Pallàs M, Lazarowski A, Beas-Zarate C, Auladell C, Camins A.

Int J Biochem Cell Biol. 2013 Jul;45(7):1377-88. doi: 10.1016/j.biocel.2013.04.011. Epub 2013 Apr 17.

PMID:
23603149
8.

Hypoxia-inducible factor-1α mediates TGF-β-induced PAI-1 production in alveolar macrophages in pulmonary fibrosis.

Ueno M, Maeno T, Nomura M, Aoyagi-Ikeda K, Matsui H, Hara K, Tanaka T, Iso T, Suga T, Kurabayashi M.

Am J Physiol Lung Cell Mol Physiol. 2011 May;300(5):L740-52. doi: 10.1152/ajplung.00146.2010. Epub 2011 Jan 14.

9.

Hypoxia-inducible factor pathway and diseases of the vascular wall.

Lim CS, Kiriakidis S, Sandison A, Paleolog EM, Davies AH.

J Vasc Surg. 2013 Jul;58(1):219-30. doi: 10.1016/j.jvs.2013.02.240. Epub 2013 Apr 30. Review.

10.

Critical role for leukocyte hypoxia inducible factor-1alpha expression in post-myocardial infarction left ventricular remodeling.

Dong F, Khalil M, Kiedrowski M, O'Connor C, Petrovic E, Zhou X, Penn MS.

Circ Res. 2010 Feb 19;106(3):601-10. doi: 10.1161/CIRCRESAHA.109.208967. Epub 2009 Dec 24.

11.

Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer.

Schwab LP, Peacock DL, Majumdar D, Ingels JF, Jensen LC, Smith KD, Cushing RC, Seagroves TN.

Breast Cancer Res. 2012 Jan 7;14(1):R6.

12.

Brain-specific knock-out of hypoxia-inducible factor-1alpha reduces rather than increases hypoxic-ischemic damage.

Helton R, Cui J, Scheel JR, Ellison JA, Ames C, Gibson C, Blouw B, Ouyang L, Dragatsis I, Zeitlin S, Johnson RS, Lipton SA, Barlow C.

J Neurosci. 2005 Apr 20;25(16):4099-107. Erratum in: J Neurosci. 2005 May 11;25(19):1 p following 4888.

13.

Cutting edge: Essential role of hypoxia inducible factor-1alpha in development of lipopolysaccharide-induced sepsis.

Peyssonnaux C, Cejudo-Martin P, Doedens A, Zinkernagel AS, Johnson RS, Nizet V.

J Immunol. 2007 Jun 15;178(12):7516-9.

14.

Expression of HIF-1alpha in injured arteries controls SDF-1alpha mediated neointima formation in apolipoprotein E deficient mice.

Karshovska E, Zernecke A, Sevilmis G, Millet A, Hristov M, Cohen CD, Schmid H, Krotz F, Sohn HY, Klauss V, Weber C, Schober A.

Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2540-7. Epub 2007 Oct 11.

16.

Intracellular pathogen Leishmania donovani activates hypoxia inducible factor-1 by dual mechanism for survival advantage within macrophage.

Singh AK, Mukhopadhyay C, Biswas S, Singh VK, Mukhopadhyay CK.

PLoS One. 2012;7(6):e38489. doi: 10.1371/journal.pone.0038489. Epub 2012 Jun 12.

17.

Lack of hypoxia-inducible factor-1 alpha impairs midbrain neural precursor cells involving vascular endothelial growth factor signaling.

Milosevic J, Maisel M, Wegner F, Leuchtenberger J, Wenger RH, Gerlach M, Storch A, Schwarz J.

J Neurosci. 2007 Jan 10;27(2):412-21.

18.

VEGF-independent cell-autonomous functions of HIF-1α regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival.

Maes C, Araldi E, Haigh K, Khatri R, Van Looveren R, Giaccia AJ, Haigh JJ, Carmeliet G, Schipani E.

J Bone Miner Res. 2012 Mar;27(3):596-609. doi: 10.1002/jbmr.1487.

19.

Molecular regulation of the PAI-1 gene by hypoxia: contributions of Egr-1, HIF-1alpha, and C/EBPalpha.

Liao H, Hyman MC, Lawrence DA, Pinsky DJ.

FASEB J. 2007 Mar;21(3):935-49. Epub 2006 Dec 28.

PMID:
17197388
20.

Accumulation of HIF-1alpha under the influence of nitric oxide.

Sandau KB, Fandrey J, Brüne B.

Blood. 2001 Feb 15;97(4):1009-15.

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