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Items: 1 to 20 of 83

1.

Posttranscriptional regulation of PER1 underlies the oncogenic function of IREα.

Pluquet O, Dejeans N, Bouchecareilh M, Lhomond S, Pineau R, Higa A, Delugin M, Combe C, Loriot S, Cubel G, Dugot-Senant N, Vital A, Loiseau H, Gosline SJ, Taouji S, Hallett M, Sarkaria JN, Anderson K, Wu W, Rodriguez FJ, Rosenbaum J, Saltel F, Fernandez-Zapico ME, Chevet E.

Cancer Res. 2013 Aug 1;73(15):4732-43. doi: 10.1158/0008-5472.CAN-12-3989. Epub 2013 Jun 10.

2.

Cytoplasmic IRE1alpha-mediated XBP1 mRNA splicing in the absence of nuclear processing and endoplasmic reticulum stress.

Back SH, Lee K, Vink E, Kaufman RJ.

J Biol Chem. 2006 Jul 7;281(27):18691-706. Epub 2006 Apr 27.

3.

IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.

Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K.

J Clin Invest. 2015 Aug 3;125(8):3269-79. doi: 10.1172/JCI76765. Epub 2015 Jul 20.

4.

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response.

Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, Kaufman RJ.

Genes Dev. 2002 Feb 15;16(4):452-66.

5.

IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation.

Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, Ma H, Inoue T, Gao B, Kim H, Bu P, Guber RD, Shen X, Lee AH, Iwawaki T, Paton AW, Paton JC, Fang D, Tsai B, Yates JR 3rd, Wu H, Kersten S, Long Q, Duhamel GE, Simpson KW, Qi L.

Nat Cell Biol. 2015 Dec;17(12):1546-55. doi: 10.1038/ncb3266. Epub 2015 Nov 9.

6.

Opposing actions of Per1 and Cry2 in the regulation of Per1 target gene expression in the liver and kidney.

Richards J, All S, Skopis G, Cheng KY, Compton B, Srialluri N, Stow L, Jeffers LA, Gumz ML.

Am J Physiol Regul Integr Comp Physiol. 2013 Oct 1;305(7):R735-47. doi: 10.1152/ajpregu.00195.2013. Epub 2013 Jul 3.

7.

PKA phosphorylation couples hepatic inositol-requiring enzyme 1alpha to glucagon signaling in glucose metabolism.

Mao T, Shao M, Qiu Y, Huang J, Zhang Y, Song B, Wang Q, Jiang L, Liu Y, Han JD, Cao P, Li J, Gao X, Rui L, Qi L, Li W, Liu Y.

Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15852-7. doi: 10.1073/pnas.1107394108. Epub 2011 Sep 12.

8.

Positive contribution of IRE1α-XBP1 pathway to the expression of placental cathepsins.

Oikawa D, Iwawaki T.

Biochem Biophys Res Commun. 2013 Apr 19;433(4):426-31. doi: 10.1016/j.bbrc.2013.02.119. Epub 2013 Mar 26.

PMID:
23541586
9.

Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma.

Jiang D, Tam AB, Alagappan M, Hay MP, Gupta A, Kozak MM, Solow-Cordero DE, Lum PY, Denko NC, Giaccia AJ, Le QT, Niwa M, Koong AC.

Mol Cancer Ther. 2016 Sep;15(9):2055-65. doi: 10.1158/1535-7163.MCT-15-1023. Epub 2016 Jun 15.

10.

IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis.

So JS, Cho S, Min SH, Kimball SR, Lee AH.

Mol Cell Biol. 2015 Aug;35(16):2761-70. doi: 10.1128/MCB.00215-15. Epub 2015 Jun 1.

11.

A functional link between the co-translational protein translocation pathway and the UPR.

Plumb R, Zhang ZR, Appathurai S, Mariappan M.

Elife. 2015 May 20;4. doi: 10.7554/eLife.07426.

12.

Autocrine control of glioma cells adhesion and migration through IRE1α-mediated cleavage of SPARC mRNA.

Dejeans N, Pluquet O, Lhomond S, Grise F, Bouchecareilh M, Juin A, Meynard-Cadars M, Bidaud-Meynard A, Gentil C, Moreau V, Saltel F, Chevet E.

J Cell Sci. 2012 Sep 15;125(Pt 18):4278-87. doi: 10.1242/jcs.099291. Epub 2012 Jun 20.

13.

[Circadian rhythm variation of the clock genes Per1 and cell cycle related genes in different stages of carcinogenesis of buccal mucosa in animal model].

Tan X, Ye H, Yang K, Chen D, Tang H.

Zhonghua Kou Qiang Yi Xue Za Zhi. 2015 Jul;50(7):392-8. Chinese.

PMID:
26564741
14.

The circadian protein period 1 contributes to blood pressure control and coordinately regulates renal sodium transport genes.

Stow LR, Richards J, Cheng KY, Lynch IJ, Jeffers LA, Greenlee MM, Cain BD, Wingo CS, Gumz ML.

Hypertension. 2012 Jun;59(6):1151-6. doi: 10.1161/HYPERTENSIONAHA.112.190892. Epub 2012 Apr 23.

15.

The unfolded protein response is activated in skeletal muscle by high-fat feeding: potential role in the downregulation of protein synthesis.

Deldicque L, Cani PD, Philp A, Raymackers JM, Meakin PJ, Ashford ML, Delzenne NM, Francaux M, Baar K.

Am J Physiol Endocrinol Metab. 2010 Nov;299(5):E695-705. doi: 10.1152/ajpendo.00038.2010. Epub 2010 May 25.

16.

Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severity.

Fedeles SV, So JS, Shrikhande A, Lee SH, Gallagher AR, Barkauskas CE, Somlo S, Lee AH.

J Clin Invest. 2015 May;125(5):1955-67. doi: 10.1172/JCI78863. Epub 2015 Apr 6.

17.

The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.

Zhang K, Wong HN, Song B, Miller CN, Scheuner D, Kaufman RJ.

J Clin Invest. 2005 Feb;115(2):268-81.

18.

High epiregulin expression in human U87 glioma cells relies on IRE1α and promotes autocrine growth through EGF receptor.

Auf G, Jabouille A, Delugin M, Guérit S, Pineau R, North S, Platonova N, Maitre M, Favereaux A, Vajkoczy P, Seno M, Bikfalvi A, Minchenko D, Minchenko O, Moenner M.

BMC Cancer. 2013 Dec 13;13:597. doi: 10.1186/1471-2407-13-597.

19.

A synthetic biology approach identifies the mammalian UPR RNA ligase RtcB.

Lu Y, Liang FX, Wang X.

Mol Cell. 2014 Sep 4;55(5):758-70. doi: 10.1016/j.molcel.2014.06.032. Epub 2014 Jul 31.

20.

IRE1alpha controls cyclin A1 expression and promotes cell proliferation through XBP-1.

Thorpe JA, Schwarze SR.

Cell Stress Chaperones. 2010 Sep;15(5):497-508. doi: 10.1007/s12192-009-0163-4. Epub 2009 Dec 15.

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