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Items: 1 to 20 of 524

1.

Particulate formulations for the delivery of poly(I:C) as vaccine adjuvant.

Hafner AM, Corthésy B, Merkle HP.

Adv Drug Deliv Rev. 2013 Oct;65(10):1386-99. doi: 10.1016/j.addr.2013.05.013. Epub 2013 Jun 7. Review.

PMID:
23751781
2.

Surface-assembled poly(I:C) on PEGylated PLGA microspheres as vaccine adjuvant: APC activation and bystander cell stimulation.

Hafner AM, Corthésy B, Textor M, Merkle HP.

Int J Pharm. 2016 Nov 30;514(1):176-188. doi: 10.1016/j.ijpharm.2016.07.042.

PMID:
27863662
3.

Surface assembly of poly(I:C) on PEGylated microspheres to shield from adverse interactions with fibroblasts.

Hafner AM, Burschowsky D, Corthésy B, Textor M, Merkle HP.

J Control Release. 2012 Apr 30;159(2):204-14. doi: 10.1016/j.jconrel.2012.02.002. Epub 2012 Feb 10.

PMID:
22349184
4.

Tuning the immune response of dendritic cells to surface-assembled poly(I:C) on microspheres through synergistic interactions between phagocytic and TLR3 signaling.

Hafner AM, Corthésy B, Textor M, Merkle HP.

Biomaterials. 2011 Apr;32(10):2651-61. doi: 10.1016/j.biomaterials.2010.12.021. Epub 2011 Jan 8.

PMID:
21216459
5.

Ampligen: a potential toll-like 3 receptor adjuvant for immunotherapy of cancer.

Jasani B, Navabi H, Adams M.

Vaccine. 2009 May 26;27(25-26):3401-4. doi: 10.1016/j.vaccine.2009.01.071. Epub 2009 Feb 5.

PMID:
19200817
6.

Immunity by formulation design: induction of high CD8+ T-cell responses by poly(I:C) incorporated into the CAF01 adjuvant via a double emulsion method.

Nordly P, Rose F, Christensen D, Nielsen HM, Andersen P, Agger EM, Foged C.

J Control Release. 2011 Mar 30;150(3):307-17. doi: 10.1016/j.jconrel.2010.11.021. Epub 2010 Nov 25.

PMID:
21111765
7.

Reprint of Neutrophil cell surface receptors and their intracellular signal transduction pathways.

Futosi K, Fodor S, Mócsai A.

Int Immunopharmacol. 2013 Dec;17(4):1185-97. doi: 10.1016/j.intimp.2013.11.010. Epub 2013 Nov 18. Review.

PMID:
24263067
8.

Co-stimulation with TLR3 and TLR21 ligands synergistically up-regulates Th1-cytokine IFN-γ and regulatory cytokine IL-10 expression in chicken monocytes.

He H, Genovese KJ, Swaggerty CL, MacKinnon KM, Kogut MH.

Dev Comp Immunol. 2012 Apr;36(4):756-60. doi: 10.1016/j.dci.2011.11.006. Epub 2011 Nov 18.

PMID:
22120532
9.

The stimulation of CD8+ T cells by dendritic cells pulsed with polyketal microparticles containing ion-paired protein antigen and poly(inosinic acid)-poly(cytidylic acid).

Heffernan MJ, Kasturi SP, Yang SC, Pulendran B, Murthy N.

Biomaterials. 2009 Feb;30(5):910-8. doi: 10.1016/j.biomaterials.2008.10.034. Epub 2008 Nov 25.

10.

Immunoadjuvant effects of polyadenylic:polyuridylic acids through TLR3 and TLR7.

Sugiyama T, Hoshino K, Saito M, Yano T, Sasaki I, Yamazaki C, Akira S, Kaisho T.

Int Immunol. 2008 Jan;20(1):1-9. Epub 2007 Nov 1.

PMID:
17981792
11.

Cationic polypeptide micelle-based antigen delivery system: a simple and robust adjuvant to improve vaccine efficacy.

Luo Z, Li P, Deng J, Gao N, Zhang Y, Pan H, Liu L, Wang C, Cai L, Ma Y.

J Control Release. 2013 Sep 10;170(2):259-67. doi: 10.1016/j.jconrel.2013.05.027. Epub 2013 Jun 3.

PMID:
23742880
12.

Not all polyriboinosinic-polyribocytidylic acids (Poly I:C) are equivalent for inducing maturation of dendritic cells: implication for alpha-type-1 polarized DCs.

Avril T, de Tayrac M, Leberre C, Quillien V.

J Immunother. 2009 May;32(4):353-62. doi: 10.1097/CJI.0b013e31819d29bf.

PMID:
19342970
14.

Biodegradable nanoparticle mediated antigen delivery to human cord blood derived dendritic cells for induction of primary T cell responses.

Diwan M, Elamanchili P, Lane H, Gainer A, Samuel J.

J Drug Target. 2003;11(8-10):495-507.

PMID:
15203918
15.

Identification of immune factors regulating antitumor immunity using polymeric vaccines with multiple adjuvants.

Ali OA, Verbeke C, Johnson C, Sands RW, Lewin SA, White D, Doherty E, Dranoff G, Mooney DJ.

Cancer Res. 2014 Mar 15;74(6):1670-81. doi: 10.1158/0008-5472.CAN-13-0777. Epub 2014 Jan 30.

16.

Mechanisms and pathways of innate immune activation and regulation in health and cancer.

Cui J, Chen Y, Wang HY, Wang RF.

Hum Vaccin Immunother. 2014;10(11):3270-85. doi: 10.4161/21645515.2014.979640. Review.

17.

Regulation of the MIR155 host gene in physiological and pathological processes.

Elton TS, Selemon H, Elton SM, Parinandi NL.

Gene. 2013 Dec 10;532(1):1-12. doi: 10.1016/j.gene.2012.12.009. Epub 2012 Dec 14. Review.

PMID:
23246696
18.

The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine.

Trumpfheller C, Caskey M, Nchinda G, Longhi MP, Mizenina O, Huang Y, Schlesinger SJ, Colonna M, Steinman RM.

Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2574-9. doi: 10.1073/pnas.0711976105. Epub 2008 Feb 6.

19.

Intracellular delivery of major histocompatibility complex class I-binding epitopes: dendritic cells loaded and matured with cationic peptide/poly(I:C) complexes efficiently activate T cells.

Haenssle HA, Riedl P, Buhl T, Schardt A, Rosenberger A, Schön MP, Schirmbeck R.

Exp Dermatol. 2010 Jan;19(1):19-28. doi: 10.1111/j.1600-0625.2009.00954.x. Epub 2009 Sep 16.

PMID:
19758325
20.

Signal regulatory protein alpha negatively regulates both TLR3 and cytoplasmic pathways in type I interferon induction.

Dong LW, Kong XN, Yan HX, Yu LX, Chen L, Yang W, Liu Q, Huang DD, Wu MC, Wang HY.

Mol Immunol. 2008 Jun;45(11):3025-35. doi: 10.1016/j.molimm.2008.03.012. Epub 2008 May 8.

PMID:
18471880

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