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Items: 1 to 20 of 109

1.

Chronic activation of the low affinity site of β1-adrenoceptors stimulates haemodynamics but exacerbates pressure-overload cardiac remodelling.

Kiriazis H, Tugiono N, Xu Q, Gao XM, Jennings NL, Ming Z, Su Y, Klenowski P, Summers RJ, Kaumann A, Molenaar P, Du XJ.

Br J Pharmacol. 2013 Sep;170(2):352-65. doi: 10.1111/bph.12272.

2.

Human atrial β(1L)-adrenoceptor but not β₃-adrenoceptor activation increases force and Ca(2+) current at physiological temperature.

Christ T, Molenaar P, Klenowski PM, Ravens U, Kaumann AJ.

Br J Pharmacol. 2011 Feb;162(4):823-39. doi: 10.1111/j.1476-5381.2010.00996.x.

3.

Knockout of beta(1)- and beta(2)-adrenoceptors attenuates pressure overload-induced cardiac hypertrophy and fibrosis.

Kiriazis H, Wang K, Xu Q, Gao XM, Ming Z, Su Y, Moore XL, Lambert G, Gibbs ME, Dart AM, Du XJ.

Br J Pharmacol. 2008 Feb;153(4):684-92. doi: 10.1038/sj.bjp.0707622. Epub 2008 Jan 14.

4.

BMP-7 attenuates left ventricular remodelling under pressure overload and facilitates reverse remodelling and functional recovery.

Merino D, Villar AV, García R, Tramullas M, Ruiz L, Ribas C, Cabezudo S, Nistal JF, Hurlé MA.

Cardiovasc Res. 2016 Jun 1;110(3):331-45. doi: 10.1093/cvr/cvw076. Epub 2016 Apr 11.

PMID:
27068510
5.

Comparison of pharmacodynamics between carvedilol and metoprolol in rats with isoproterenol-induced cardiac hypertrophy: effects of carvedilol enantiomers.

Hanada K, Asari K, Saito M, Kawana J, Mita M, Ogata H.

Eur J Pharmacol. 2008 Jul 28;589(1-3):194-200. doi: 10.1016/j.ejphar.2008.04.055. Epub 2008 May 6.

PMID:
18534575
6.

CGP12177-induced haemodynamic and vascular effects in normotensive and hypertensive rats.

Holopherne D, Mallem MY, Le Strat E, Belin de Chantemèle EJ, Gogny M, Henrion D, Noireaud J, Desfontis JC.

Eur J Pharmacol. 2008 Sep 4;591(1-3):196-202. doi: 10.1016/j.ejphar.2008.06.060. Epub 2008 Jun 19.

PMID:
18601917
7.

MH-3: evidence for non-competitive antagonism towards the low-affinity site of β1-adrenoceptors.

Schlicker E, Pędzińska-Betiuk A, Kozłowska H, Szkaradek N, Żelaszczyk D, Baranowska-Kuczko M, Kieć-Kononowicz K, Marona H, Malinowska B.

Naunyn Schmiedebergs Arch Pharmacol. 2014 Aug;387(8):743-52. doi: 10.1007/s00210-014-0983-3. Epub 2014 May 3.

PMID:
24788554
8.

Effect of beta-blockers on beta3-adrenoceptor expression in chronic heart failure.

Zhao Q, Wu TG, Jiang ZF, Chen GW, Lin Y, Wang LX.

Cardiovasc Drugs Ther. 2007 Apr;21(2):85-90.

PMID:
17440824
9.

Celiprolol, a vasodilatory beta-blocker, inhibits pressure overload-induced cardiac hypertrophy and prevents the transition to heart failure via nitric oxide-dependent mechanisms in mice.

Liao Y, Asakura M, Takashima S, Ogai A, Asano Y, Shintani Y, Minamino T, Asanuma H, Sanada S, Kim J, Kitamura S, Tomoike H, Hori M, Kitakaze M.

Circulation. 2004 Aug 10;110(6):692-9. Epub 2004 Jul 19.

PMID:
15262839
10.

The low-affinity site of the beta1-adrenoceptor and its relevance to cardiovascular pharmacology.

Kaumann AJ, Molenaar P.

Pharmacol Ther. 2008 Jun;118(3):303-36. doi: 10.1016/j.pharmthera.2008.03.009. Epub 2008 Apr 11. Review.

PMID:
18501968
12.

Aspartate138 is required for the high-affinity ligand binding site but not for the low-affinity binding site of the beta1-adrenoceptor.

Joseph SS, Colledge WH, Kaumann AJ.

Naunyn Schmiedebergs Arch Pharmacol. 2004 Sep;370(3):223-6. Epub 2004 Aug 18.

PMID:
15322738
13.

Beneficial effect of the central nervous system beta-adrenoceptor blockade on the failing heart.

Gourine A, Bondar SI, Spyer KM, Gourine AV.

Circ Res. 2008 Mar 28;102(6):633-6. doi: 10.1161/CIRCRESAHA.107.165183. Epub 2008 Mar 6.

PMID:
18323523
14.

Eicosapentaenoic acid suppresses adverse effects of C-reactive protein overexpression on pressure overload-induced cardiac remodeling.

Nagai T, Anzai T, Mano Y, Kaneko H, Anzai A, Sugano Y, Maekawa Y, Takahashi T, Yoshikawa T, Fukuda K.

Heart Vessels. 2013 May;28(3):404-11. doi: 10.1007/s00380-012-0270-5. Epub 2012 Aug 9.

PMID:
22875408
15.

The role of cardiac beta1- and beta2-adrenoceptor stimulation in heart failure.

Khamssi M, Brodde OE.

J Cardiovasc Pharmacol. 1990;16 Suppl 5:S133-7. Review.

PMID:
11527117
16.
17.

Distinct role of adrenoceptor subtypes in cardiac adaptation to chronic pressure overload.

Du XJ.

Clin Exp Pharmacol Physiol. 2008 Mar;35(3):355-60. doi: 10.1111/j.1440-1681.2007.04871.x.

PMID:
18290877
18.

Chronic bilateral renal denervation reduces cardiac hypertrophic remodelling but not β-adrenergic responsiveness in hypertensive type 1 diabetic rats.

Thaung HP, Yao Y, Bussey CT, Hughes G, Jones PP, Bahn A, Sammut IA, Lamberts RR.

Exp Physiol. 2015 Jun;100(6):628-39. doi: 10.1113/EP085021.

19.

Lack of Gαi2 leads to dilative cardiomyopathy and increased mortality in β1-adrenoceptor overexpressing mice.

Keller K, Maass M, Dizayee S, Leiss V, Annala S, Köth J, Seemann WK, Müller-Ehmsen J, Mohr K, Nürnberg B, Engelhardt S, Herzig S, Birnbaumer L, Matthes J.

Cardiovasc Res. 2015 Dec 1;108(3):348-56. doi: 10.1093/cvr/cvv235. Epub 2015 Oct 13.

20.

Reduced CGP12177 binding to cardiac β-adrenoceptors in hyperglycemic high-fat-diet-fed, streptozotocin-induced diabetic rats.

Thackeray JT, Parsa-Nezhad M, Kenk M, Thorn SL, Kolajova M, Beanlands RS, DaSilva JN.

Nucl Med Biol. 2011 Oct;38(7):1059-66. doi: 10.1016/j.nucmedbio.2011.04.002. Epub 2011 Aug 9.

PMID:
21831645

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