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Items: 1 to 20 of 103

1.

Serum iron levels and the risk of Parkinson disease: a Mendelian randomization study.

Pichler I, Del Greco M F, Gögele M, Lill CM, Bertram L, Do CB, Eriksson N, Foroud T, Myers RH; PD GWAS Consortium, Nalls M, Keller MF; International Parkinson's Disease Genomics Consortium; Wellcome Trust Case Control Consortium 2, Benyamin B, Whitfield JB; Genetics of Iron Status Consortium, Pramstaller PP, Hicks AA, Thompson JR, Minelli C.

PLoS Med. 2013;10(6):e1001462. doi: 10.1371/journal.pmed.1001462. Epub 2013 Jun 4. Erratum in: PLoS Med. 2013 Jun;10(6). doi:10.1371/annotation/c4d81646-0c0e-4a3e-9425-b220bae2d8b6.

2.

Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study.

Noyce AJ, Kia DA, Hemani G, Nicolas A, Price TR, De Pablo-Fernandez E, Haycock PC, Lewis PA, Foltynie T, Davey Smith G; International Parkinson Disease Genomics Consortium, Schrag A, Lees AJ, Hardy J, Singleton A, Nalls MA, Pearce N, Lawlor DA, Wood NW.

PLoS Med. 2017 Jun 13;14(6):e1002314. doi: 10.1371/journal.pmed.1002314. eCollection 2017 Jun.

3.

Serum iron level and kidney function: a Mendelian randomization study.

Del Greco M F, Foco L, Pichler I, Eller P, Eller K, Benyamin B, Whitfield JB; Genetics of Iron Status Consortium; CKDGen Consortium, Pramstaller PP, Thompson JR, Pattaro C, Minelli C.

Nephrol Dial Transplant. 2017 Feb 1;32(2):273-278. doi: 10.1093/ndt/gfw215.

PMID:
28186534
4.

Haptoglobin phenotype modifies serum iron levels and the effect of smoking on Parkinson disease risk.

Costa-Mallen P, Zabetian CP, Agarwal P, Hu SC, Yearout D, Samii A, Leverenz JB, Roberts JW, Checkoway H.

Parkinsonism Relat Disord. 2015 Sep;21(9):1087-92. doi: 10.1016/j.parkreldis.2015.07.006. Epub 2015 Jul 10.

5.

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression.

Bowden J, Davey Smith G, Burgess S.

Int J Epidemiol. 2015 Apr;44(2):512-25. doi: 10.1093/ije/dyv080. Epub 2015 Jun 6.

6.

Mendelian randomization of serum urate and parkinson disease progression.

Simon KC, Eberly S, Gao X, Oakes D, Tanner CM, Shoulson I, Fahn S, Schwarzschild MA, Ascherio A; Parkinson Study Group.

Ann Neurol. 2014 Dec;76(6):862-8. doi: 10.1002/ana.24281. Epub 2014 Oct 3.

7.

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator.

Bowden J, Davey Smith G, Haycock PC, Burgess S.

Genet Epidemiol. 2016 May;40(4):304-14. doi: 10.1002/gepi.21965. Epub 2016 Apr 7.

8.

Examination of HFE associations with childhood leukemia risk and extension to other iron regulatory genes.

Kennedy AE, Kamdar KY, Lupo PJ, Okcu MF, Scheurer ME, Baum MK, Dorak MT.

Leuk Res. 2014 Sep;38(9):1055-60. doi: 10.1016/j.leukres.2014.06.016. Epub 2014 Jul 11.

PMID:
25085015
9.

Resequencing analysis of five Mendelian genes and the top genes from genome-wide association studies in Parkinson's Disease.

Benitez BA, Davis AA, Jin SC, Ibanez L, Ortega-Cubero S, Pastor P, Choi J, Cooper B, Perlmutter JS, Cruchaga C.

Mol Neurodegener. 2016 Apr 19;11:29. doi: 10.1186/s13024-016-0097-0.

10.

Association of TMPRSS6 polymorphisms with ferritin, hemoglobin, and type 2 diabetes risk in a Chinese Han population.

Gan W, Guan Y, Wu Q, An P, Zhu J, Lu L, Jing L, Yu Y, Ruan S, Xie D, Makrides M, Gibson RA, Anderson GJ, Li H, Lin X, Wang F.

Am J Clin Nutr. 2012 Mar;95(3):626-32. doi: 10.3945/ajcn.111.025684. Epub 2012 Feb 1.

11.

Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis.

Proitsi P, Lupton MK, Velayudhan L, Newhouse S, Fogh I, Tsolaki M, Daniilidou M, Pritchard M, Kloszewska I, Soininen H, Mecocci P, Vellas B; Alzheimer's Disease Neuroimaging Initiative, Williams J; GERAD1 Consortium, Stewart R, Sham P, Lovestone S, Powell JF.

PLoS Med. 2014 Sep 16;11(9):e1001713. doi: 10.1371/journal.pmed.1001713. eCollection 2014 Sep.

12.

The association between the C282Y and H63D polymorphisms of HFE gene and the risk of Parkinson's disease: A meta-analysis.

Xia J, Xu H, Jiang H, Xie J.

Neurosci Lett. 2015 May 19;595:99-103. doi: 10.1016/j.neulet.2015.04.010. Epub 2015 Apr 8.

PMID:
25863172
13.

Serum total bilirubin levels and coronary heart disease--Causal association or epiphenomenon?

Kunutsor SK.

Exp Gerontol. 2015 Dec;72:63-6. doi: 10.1016/j.exger.2015.09.014. Epub 2015 Sep 25.

PMID:
26408227
14.

BMI as a Modifiable Risk Factor for Type 2 Diabetes: Refining and Understanding Causal Estimates Using Mendelian Randomization.

Corbin LJ, Richmond RC, Wade KH, Burgess S, Bowden J, Smith GD, Timpson NJ.

Diabetes. 2016 Oct;65(10):3002-7. doi: 10.2337/db16-0418. Epub 2016 Jul 8.

15.

Mendelian randomization suggests non-causal associations of testosterone with cardiometabolic risk factors and mortality.

Haring R, Teumer A, Völker U, Dörr M, Nauck M, Biffar R, Völzke H, Baumeister SE, Wallaschofski H.

Andrology. 2013 Jan;1(1):17-23. doi: 10.1111/j.2047-2927.2012.00002.x. Epub 2012 Aug 26.

16.

Associations of common variants in HFE and TMPRSS6 with iron parameters are independent of serum hepcidin in a general population: a replication study.

Galesloot TE, Geurts-Moespot AJ, den Heijer M, Sweep FC, Fleming RE, Kiemeney LA, Vermeulen SH, Swinkels DW.

J Med Genet. 2013 Sep;50(9):593-8. doi: 10.1136/jmedgenet-2013-101673. Epub 2013 Jun 21.

PMID:
23794717
17.

Mendelian randomization analysis with multiple genetic variants using summarized data.

Burgess S, Butterworth A, Thompson SG.

Genet Epidemiol. 2013 Nov;37(7):658-65. doi: 10.1002/gepi.21758. Epub 2013 Sep 20.

18.

No clear support for a role for vitamin D in Parkinson's disease: A Mendelian randomization study.

Larsson SC, Singleton AB, Nalls MA, Richards JB; International Parkinson's Disease Genomics Consortium (IPDGC).

Mov Disord. 2017 Jun 8. doi: 10.1002/mds.27069. [Epub ahead of print]

PMID:
28594127
19.

Mendelian randomization studies in coronary artery disease.

Jansen H, Samani NJ, Schunkert H.

Eur Heart J. 2014 Aug 1;35(29):1917-24. doi: 10.1093/eurheartj/ehu208. Epub 2014 Jun 10. Review.

20.

Analysis of genome-wide association studies of Alzheimer disease and of Parkinson disease to determine if these 2 diseases share a common genetic risk.

Moskvina V, Harold D, Russo G, Vedernikov A, Sharma M, Saad M, Holmans P, Bras JM, Bettella F, Keller MF, Nicolaou N, Simón-Sánchez J, Gibbs JR, Schulte C, Durr A, Guerreiro R, Hernandez D, Brice A, Stefánsson H, Majamaa K, Gasser T, Heutink P, Wood N, Martinez M, Singleton AB, Nalls MA, Hardy J, Owen MJ, O'Donovan MC, Williams J, Morris HR, Williams NM; IPDGC and GERAD Investigators.

JAMA Neurol. 2013 Oct;70(10):1268-76.

PMID:
23921447

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