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Items: 1 to 20 of 287

1.

CHOP-mediated hepcidin suppression modulates hepatic iron load.

Mueller K, Sunami Y, Stuetzle M, Guldiken N, Kucukoglu O, Mueller S, Kulaksiz H, Schwarz P, Strnad P.

J Pathol. 2013 Dec;231(4):532-42. doi: 10.1002/path.4221. Epub 2013 Oct 15.

PMID:
23749468
2.

Hepcidin is down-regulated in alcoholic liver injury: implications for the pathogenesis of alcoholic liver disease.

Bridle K, Cheung TK, Murphy T, Walters M, Anderson G, Crawford DG, Fletcher LM.

Alcohol Clin Exp Res. 2006 Jan;30(1):106-12.

PMID:
16433737
3.

C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism.

Courselaud B, Pigeon C, Inoue Y, Inoue J, Gonzalez FJ, Leroyer P, Gilot D, Boudjema K, Guguen-Guillouzo C, Brissot P, Loréal O, Ilyin G.

J Biol Chem. 2002 Oct 25;277(43):41163-70. Epub 2002 Aug 14.

4.

Liver hepcidin mRNA expression is inappropriately low in alcoholic patients compared with healthy controls.

Costa-Matos L, Batista P, Monteiro N, Simões M, Egas C, Pereira J, Pinho H, Santos N, Ribeiro J, Cipriano MA, Henriques P, Girão F, Rodrigues A, Carvalho A.

Eur J Gastroenterol Hepatol. 2012 Oct;24(10):1158-65. doi: 10.1097/MEG.0b013e328355cfd0.

PMID:
22732356
5.

Alcohol metabolism-mediated oxidative stress down-regulates hepcidin transcription and leads to increased duodenal iron transporter expression.

Harrison-Findik DD, Schafer D, Klein E, Timchenko NA, Kulaksiz H, Clemens D, Fein E, Andriopoulos B, Pantopoulos K, Gollan J.

J Biol Chem. 2006 Aug 11;281(32):22974-82. Epub 2006 May 31.

6.

Heat stress stimulates hepcidin mRNA expression and C/EBPα protein expression in aged rodent liver.

Bloomer SA, Kregel KC, Brown KE.

Arch Gerontol Geriatr. 2014 Jan-Feb;58(1):145-52. doi: 10.1016/j.archger.2013.07.012. Epub 2013 Aug 8.

7.

Hepatitis C virus-induced reactive oxygen species raise hepatic iron level in mice by reducing hepcidin transcription.

Nishina S, Hino K, Korenaga M, Vecchi C, Pietrangelo A, Mizukami Y, Furutani T, Sakai A, Okuda M, Hidaka I, Okita K, Sakaida I.

Gastroenterology. 2008 Jan;134(1):226-38. doi: 10.1053/j.gastro.2007.10.011. Epub 2007 Oct 9.

PMID:
18166355
8.

Quercetin prevents ethanol-induced iron overload by regulating hepcidin through the BMP6/SMAD4 signaling pathway.

Tang Y, Li Y, Yu H, Gao C, Liu L, Chen S, Xing M, Liu L, Yao P.

J Nutr Biochem. 2014 Jun;25(6):675-82. doi: 10.1016/j.jnutbio.2014.02.009. Epub 2014 Mar 19.

PMID:
24746831
9.

Hepcidin knockout mice fed with iron-rich diet develop chronic liver injury and liver fibrosis due to lysosomal iron overload.

Lunova M, Goehring C, Kuscuoglu D, Mueller K, Chen Y, Walther P, Deschemin JC, Vaulont S, Haybaeck J, Lackner C, Trautwein C, Strnad P.

J Hepatol. 2014 Sep;61(3):633-41. doi: 10.1016/j.jhep.2014.04.034. Epub 2014 May 6.

PMID:
24816174
10.

[The effect of alcohol on the regulation of iron metabolism].

Cylwik B, Chrostek L, Szmitkowski M.

Pol Merkur Lekarski. 2008 Sep;25(147):273-5. Review. Polish.

PMID:
19112848
11.

BMP type II receptors have redundant roles in the regulation of hepatic hepcidin gene expression and iron metabolism.

Mayeur C, Leyton PA, Kolodziej SA, Yu B, Bloch KD.

Blood. 2014 Sep 25;124(13):2116-23. doi: 10.1182/blood-2014-04-572644. Epub 2014 Jul 29.

12.

Iron-mediated regulation of liver hepcidin expression in rats and mice is abolished by alcohol.

Harrison-Findik DD, Klein E, Crist C, Evans J, Timchenko N, Gollan J.

Hepatology. 2007 Dec;46(6):1979-85.

PMID:
17763462
13.

IL-22 regulates iron availability in vivo through the induction of hepcidin.

Smith CL, Arvedson TL, Cooke KS, Dickmann LJ, Forte C, Li H, Merriam KL, Perry VK, Tran L, Rottman JB, Maxwell JR.

J Immunol. 2013 Aug 15;191(4):1845-55. doi: 10.4049/jimmunol.1202716. Epub 2013 Jul 8.

14.

Bone morphogenetic protein-binding endothelial regulator of liver sinusoidal endothelial cells induces iron overload in a fatty liver mouse model.

Hasebe T, Tanaka H, Sawada K, Nakajima S, Ohtake T, Fujiya M, Kohgo Y.

J Gastroenterol. 2017 Mar;52(3):341-351. doi: 10.1007/s00535-016-1237-6. Epub 2016 Jun 30.

15.

Hepcidin is down-regulated in alcohol loading.

Ohtake T, Saito H, Hosoki Y, Inoue M, Miyoshi S, Suzuki Y, Fujimoto Y, Kohgo Y.

Alcohol Clin Exp Res. 2007 Jan;31(1 Suppl):S2-8.

PMID:
17331161
16.

Upregulation of iron regulatory hormone hepcidin by interferon α.

Ichiki K, Ikuta K, Addo L, Tanaka H, Sasaki Y, Shimonaka Y, Sasaki K, Ito S, Shindo M, Ohtake T, Fujiya M, Torimoto Y, Kohgo Y.

J Gastroenterol Hepatol. 2014 Feb;29(2):387-94. doi: 10.1111/jgh.12348.

PMID:
23926964
17.

Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin.

Latour C, Kautz L, Besson-Fournier C, Island ML, Canonne-Hergaux F, Loréal O, Ganz T, Coppin H, Roth MP.

Hepatology. 2014 Feb;59(2):683-94. doi: 10.1002/hep.26648. Epub 2013 Dec 16.

PMID:
23907767
18.

Hepcidin is directly regulated by insulin and plays an important role in iron overload in streptozotocin-induced diabetic rats.

Wang H, Li H, Jiang X, Shi W, Shen Z, Li M.

Diabetes. 2014 May;63(5):1506-18. doi: 10.2337/db13-1195. Epub 2013 Dec 30.

19.

Effects of iron overload condition on liver toxicity and hepcidin/ferroportin expression in thalassemic mice.

Kumfu S, Chattipakorn SC, Fucharoen S, Chattipakorn N.

Life Sci. 2016 Apr 1;150:15-23. doi: 10.1016/j.lfs.2016.02.082. Epub 2016 Feb 24.

PMID:
26921633
20.

Inhibition of hepcidin transcription by growth factors.

Goodnough JB, Ramos E, Nemeth E, Ganz T.

Hepatology. 2012 Jul;56(1):291-9. doi: 10.1002/hep.25615. Epub 2012 Jun 18.

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