Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 243

1.

Gastrointestinal pain: unraveling a novel endogenous pathway through uroguanylin/guanylate cyclase-C/cGMP activation.

Silos-Santiago I, Hannig G, Eutamene H, Ustinova EE, Bernier SG, Ge P, Graul C, Jacobson S, Jin H, Liong E, Kessler MM, Reza T, Rivers S, Shea C, Tchernychev B, Bryant AP, Kurtz CB, Bueno L, Pezzone MA, Currie MG.

Pain. 2013 Sep;154(9):1820-30. doi: 10.1016/j.pain.2013.05.044. Epub 2013 Jun 5.

2.

Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate.

Castro J, Harrington AM, Hughes PA, Martin CM, Ge P, Shea CM, Jin H, Jacobson S, Hannig G, Mann E, Cohen MB, MacDougall JE, Lavins BJ, Kurtz CB, Silos-Santiago I, Johnston JM, Currie MG, Blackshaw LA, Brierley SM.

Gastroenterology. 2013 Dec;145(6):1334-46.e1-11. doi: 10.1053/j.gastro.2013.08.017. Epub 2013 Aug 16.

3.

Guanylate cyclase C-mediated antinociceptive effects of linaclotide in rodent models of visceral pain.

Eutamene H, Bradesi S, Larauche M, Theodorou V, Beaufrand C, Ohning G, Fioramonti J, Cohen M, Bryant AP, Kurtz C, Currie MG, Mayer EA, Bueno L.

Neurogastroenterol Motil. 2010 Mar;22(3):312-e84. doi: 10.1111/j.1365-2982.2009.01385.x. Epub 2009 Aug 25.

4.

MRP4 Modulation of the Guanylate Cyclase-C/cGMP Pathway: Effects on Linaclotide-Induced Electrolyte Secretion and cGMP Efflux.

Tchernychev B, Ge P, Kessler MM, Solinga RM, Wachtel D, Tobin JV, Thomas SR, Lunte CE, Fretzen A, Hannig G, Bryant AP, Kurtz CB, Currie MG, Silos-Santiago I.

J Pharmacol Exp Ther. 2015 Oct;355(1):48-56. doi: 10.1124/jpet.115.224329. Epub 2015 Jul 27.

5.

Uroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMP.

Shailubhai K, Yu HH, Karunanandaa K, Wang JY, Eber SL, Wang Y, Joo NS, Kim HD, Miedema BW, Abbas SZ, Boddupalli SS, Currie MG, Forte LR.

Cancer Res. 2000 Sep 15;60(18):5151-7.

6.
7.

Uroguanylin and guanylin regulate transport of mouse cortical collecting duct independent of guanylate cyclase C.

Sindić A, Velic A, Başoglu C, Hirsch JR, Edemir B, Kuhn M, Schlatter E.

Kidney Int. 2005 Sep;68(3):1008-17.

8.

Renal effects of uroguanylin and guanylin in vivo.

Carrithers SL, Hill MJ, Johnson BR, O'Hara SM, Jackson BA, Ott CE, Lorenz J, Mann EA, Giannella RA, Forte LR, Greenberg RN.

Braz J Med Biol Res. 1999 Nov;32(11):1337-44.

9.

Guanylin peptides: cyclic GMP signaling mechanisms.

Forte LR, Freeman RH, Krause WJ, London RM.

Braz J Med Biol Res. 1999 Nov;32(11):1329-36.

10.

Guanylin, uroguanylin, and heat-stable euterotoxin activate guanylate cyclase C and/or a pertussis toxin-sensitive G protein in human proximal tubule cells.

Sindiće A, Başoglu C, Cerçi A, Hirsch JR, Potthast R, Kuhn M, Ghanekar Y, Visweswariah SS, Schlatter E.

J Biol Chem. 2002 May 17;277(20):17758-64. Epub 2002 Mar 21.

11.

Signal transduction pathways via guanylin and uroguanylin in stomach and intestine.

London RM, Krause WJ, Fan X, Eber SL, Forte LR.

Am J Physiol. 1997 Jul;273(1 Pt 1):G93-105.

PMID:
9252514
12.

Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit.

Busby RW, Bryant AP, Bartolini WP, Cordero EA, Hannig G, Kessler MM, Mahajan-Miklos S, Pierce CM, Solinga RM, Sun LJ, Tobin JV, Kurtz CB, Currie MG.

Eur J Pharmacol. 2010 Dec 15;649(1-3):328-35. doi: 10.1016/j.ejphar.2010.09.019. Epub 2010 Sep 20.

PMID:
20863829
13.

Opossum colonic mucosa contains uroguanylin and guanylin peptides.

Hamra FK, Krause WJ, Eber SL, Freeman RH, Smith CE, Currie MG, Forte LR.

Am J Physiol. 1996 Apr;270(4 Pt 1):G708-16.

PMID:
8928802
14.

Guanylate cyclase-C/cGMP: an emerging pathway in the regulation of visceral pain.

Hannig G, Tchernychev B, Kurtz CB, Bryant AP, Currie MG, Silos-Santiago I.

Front Mol Neurosci. 2014 Apr 16;7:31. doi: 10.3389/fnmol.2014.00031. eCollection 2014. Review.

15.

Guanylin peptides: renal actions mediated by cyclic GMP.

Forte LR, London RM, Freeman RH, Krause WJ.

Am J Physiol Renal Physiol. 2000 Feb;278(2):F180-91. Review.

16.

Salt and water homeostasis: uroguanylin is a circulating peptide hormone with natriuretic activity.

Forte LR, Fan X, Hamra FK.

Am J Kidney Dis. 1996 Aug;28(2):296-304. Review.

PMID:
8768930
18.

Synthesis, biological activity and isomerism of guanylate cyclase C-activating peptides guanylin and uroguanylin.

Klodt J, Kuhn M, Marx UC, Martin S, Rösch P, Forssmann WG, Adermann K.

J Pept Res. 1997 Sep;50(3):222-30.

PMID:
9309586
19.

Interaction of atrial natriuretic peptide, urodilatin, guanylin and uroguanylin in the isolated perfused rat kidney.

Santos-Neto MS, Carvalho AF, Monteiro HS, Forte LR, Fonteles MC.

Regul Pept. 2006 Sep 11;136(1-3):14-22. Epub 2006 Jun 30.

PMID:
16814407
20.

Structure and activity of uroguanylin and guanylin from the intestine and urine of rats.

Fan X, Hamra FK, London RM, Eber SL, Krause WJ, Freeman RH, Smith CE, Currie MG, Forte LR.

Am J Physiol. 1997 Nov;273(5 Pt 1):E957-64.

Supplemental Content

Support Center