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Items: 1 to 20 of 110

1.

TNF-related weak inducer of apoptosis (TWEAK) promotes kidney fibrosis and Ras-dependent proliferation of cultured renal fibroblast.

Ucero AC, Benito-Martin A, Fuentes-Calvo I, Santamaria B, Blanco J, Lopez-Novoa JM, Ruiz-Ortega M, Egido J, Burkly LC, Martinez-Salgado C, Ortiz A.

Biochim Biophys Acta. 2013 Oct;1832(10):1744-55. doi: 10.1016/j.bbadis.2013.05.032. Epub 2013 Jun 6.

2.

TWEAK, a multifunctional cytokine in kidney injury.

Sanz AB, Sanchez-Niño MD, Ortiz A.

Kidney Int. 2011 Oct;80(7):708-18. doi: 10.1038/ki.2011.180. Epub 2011 Jun 22. Review.

3.

Relevant role of PKG in the progression of fibrosis induced by TNF-like weak inducer of apoptosis.

Martín P, Mora I, Cortes MA, Calleros L, García-Jerez A, Ortiz A, Rodríguez-Puyol M, Rodríguez-Puyol D, Olmos G.

Am J Physiol Renal Physiol. 2014 Jul 1;307(1):F75-85. doi: 10.1152/ajprenal.00398.2013. Epub 2014 May 28.

4.

Tweak induces proliferation in renal tubular epithelium: a role in uninephrectomy induced renal hyperplasia.

Sanz AB, Sanchez-Niño MD, Izquierdo MC, Jakubowski A, Justo P, Blanco-Colio LM, Ruiz-Ortega M, Egido J, Ortiz A.

J Cell Mol Med. 2009 Sep;13(9B):3329-42. doi: 10.1111/j.1582-4934.2009.00766.x. Epub 2009 May 1.

5.

The cytokine TWEAK modulates renal tubulointerstitial inflammation.

Sanz AB, Justo P, Sanchez-Niño MD, Blanco-Colio LM, Winkles JA, Kreztler M, Jakubowski A, Blanco J, Egido J, Ruiz-Ortega M, Ortiz A.

J Am Soc Nephrol. 2008 Apr;19(4):695-703. doi: 10.1681/ASN.2007050577. Epub 2008 Jan 30.

6.

TWEAK and the progression of renal disease: clinical translation.

Sanz AB, Izquierdo MC, Sanchez-Niño MD, Ucero AC, Egido J, Ruiz-Ortega M, Ramos AM, Putterman C, Ortiz A.

Nephrol Dial Transplant. 2014 Feb;29 Suppl 1:i54-i62. doi: 10.1093/ndt/gft342. Review.

7.

Out of the TWEAKlight: Elucidating the Role of Fn14 and TWEAK in Acute Kidney Injury.

Sanz AB, Ruiz-Andres O, Sanchez-Niño MD, Ruiz-Ortega M, Ramos AM, Ortiz A.

Semin Nephrol. 2016 May;36(3):189-98. doi: 10.1016/j.semnephrol.2016.03.006. Review.

PMID:
27339384
8.

TWEAK-Fn14 Signaling Activates Myofibroblasts to Drive Progression of Fibrotic Kidney Disease.

Gomez IG, Roach AM, Nakagawa N, Amatucci A, Johnson BG, Dunn K, Kelly MC, Karaca G, Zheng TS, Szak S, Peppiatt-Wildman CM, Burkly LC, Duffield JS.

J Am Soc Nephrol. 2016 Dec;27(12):3639-3652. Epub 2016 Mar 29.

PMID:
27026366
9.

Proinflammatory effects of TWEAK/Fn14 interactions in glomerular mesangial cells.

Campbell S, Burkly LC, Gao HX, Berman JW, Su L, Browning B, Zheng T, Schiffer L, Michaelson JS, Putterman C.

J Immunol. 2006 Feb 1;176(3):1889-98.

10.

Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cells.

Tirnitz-Parker JE, Viebahn CS, Jakubowski A, Klopcic BR, Olynyk JK, Yeoh GC, Knight B.

Hepatology. 2010 Jul;52(1):291-302. doi: 10.1002/hep.23663.

PMID:
20578156
11.

TWEAK (tumor necrosis factor-like weak inducer of apoptosis) activates CXCL16 expression during renal tubulointerstitial inflammation.

Izquierdo MC, Sanz AB, Mezzano S, Blanco J, Carrasco S, Sanchez-Niño MD, Benito-Martín A, Ruiz-Ortega M, Egido J, Ortiz A.

Kidney Int. 2012 Jun;81(11):1098-107. doi: 10.1038/ki.2011.475. Epub 2012 Jan 25.

12.

Cytokine cooperation in renal tubular cell injury: the role of TWEAK.

Justo P, Sanz AB, Sanchez-Niño MD, Winkles JA, Lorz C, Egido J, Ortiz A.

Kidney Int. 2006 Nov;70(10):1750-8. Epub 2006 Sep 27.

13.

TNF-related weak inducer of apoptosis (TWEAK) regulates junctional proteins in tubular epithelial cells via canonical NF-κB pathway and ERK activation.

Berzal S, González-Guerrero C, Rayego-Mateos S, Ucero Á, Ocaña-Salceda C, Egido J, Ortiz A, Ruiz-Ortega M, Ramos AM.

J Cell Physiol. 2015 Jul;230(7):1580-93. doi: 10.1002/jcp.24905.

PMID:
25536182
14.

Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) enhances vascular and renal damage induced by hyperlipidemic diet in ApoE-knockout mice.

Muñoz-García B, Moreno JA, López-Franco O, Sanz AB, Martín-Ventura JL, Blanco J, Jakubowski A, Burkly LC, Ortiz A, Egido J, Blanco-Colio LM.

Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2061-8. doi: 10.1161/ATVBAHA.109.194852. Epub 2009 Sep 24.

15.

Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation.

Wilhelm A, Shepherd EL, Amatucci A, Munir M, Reynolds G, Humphreys E, Resheq Y, Adams DH, Hübscher S, Burkly LC, Weston CJ, Afford SC.

J Pathol. 2016 May;239(1):109-21. doi: 10.1002/path.4707. Epub 2016 Mar 29.

16.

Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) and kidney disease.

Ruiz-Ortega M, Ortiz A, Ramos AM.

Curr Opin Nephrol Hypertens. 2014 Jan;23(1):93-100. doi: 10.1097/01.mnh.0000437331.23794.81. Review.

PMID:
24257157
17.

TWEAK/Fn14 pathway promotes a T helper 2-type chronic colitis with fibrosis in mice.

Son A, Oshio T, Kawamura YI, Hagiwara T, Yamazaki M, Inagaki-Ohara K, Okada T, Wu P, Iseki M, Takaki S, Burkly LC, Dohi T.

Mucosal Immunol. 2013 Nov;6(6):1131-42. doi: 10.1038/mi.2013.10. Epub 2013 Mar 6.

PMID:
23462911
18.

Roles of tumour necrosis factor-related weak inducer of apoptosis/fibroblast growth factor-inducible 14 pathway in lupus nephritis.

Chen J, Wei L, Xia Y.

Nephrology (Carlton). 2017 Feb;22(2):101-106. doi: 10.1111/nep.12957. Review.

PMID:
27786399
19.

TWEAKing renal injury.

Sanz AB, Moreno JA, Sanchez-Nino MD, Ucero AC, Benito A, Santamaria B, Justo P, Izquierdo MC, Egido J, Blanco-Colio LM, Ortiz A.

Front Biosci. 2008 Jan 1;13:580-9. Review.

PMID:
17981571
20.

TWEAK activates the non-canonical NFkappaB pathway in murine renal tubular cells: modulation of CCL21.

Sanz AB, Sanchez-Niño MD, Izquierdo MC, Jakubowski A, Justo P, Blanco-Colio LM, Ruiz-Ortega M, Selgas R, Egido J, Ortiz A.

PLoS One. 2010 Jan 29;5(1):e8955. doi: 10.1371/journal.pone.0008955.

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