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Items: 1 to 20 of 145

1.

The nuclear localization signal is required for nuclear GPER translocation and function in breast Cancer-Associated Fibroblasts (CAFs).

Pupo M, Vivacqua A, Perrotta I, Pisano A, Aquila S, Abonante S, Gasperi-Campani A, Pezzi V, Maggiolini M.

Mol Cell Endocrinol. 2013 Aug 25;376(1-2):23-32. doi: 10.1016/j.mce.2013.05.023. Epub 2013 Jun 5.

PMID:
23748028
2.

HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs).

De Francesco EM, Lappano R, Santolla MF, Marsico S, Caruso A, Maggiolini M.

Breast Cancer Res. 2013;15(4):R64.

3.

GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells.

Vivacqua A, Romeo E, De Marco P, De Francesco EM, Abonante S, Maggiolini M.

Breast Cancer Res Treat. 2012 Jun;133(3):1025-35. doi: 10.1007/s10549-011-1901-8. Epub 2011 Dec 7.

PMID:
22147081
4.

GPER activates Notch signaling in breast cancer cells and cancer-associated fibroblasts (CAFs).

Pupo M, Pisano A, Abonante S, Maggiolini M, Musti AM.

Int J Biochem Cell Biol. 2014 Jan;46:56-67. doi: 10.1016/j.biocel.2013.11.011. Epub 2013 Nov 22.

PMID:
24275097
5.

GPER in CAFs regulates hypoxia-driven breast cancer invasion in a CTGF-dependent manner.

Ren J, Guo H, Wu H, Tian T, Dong D, Zhang Y, Sui Y, Zhang Y, Zhao D, Wang S, Li Z, Zhang X, Liu R, Qian J, Wei H, Jiang W, Liu Y, Li Y.

Oncol Rep. 2015 Apr;33(4):1929-37. doi: 10.3892/or.2015.3779. Epub 2015 Feb 3.

PMID:
25647524
6.

GPER Mediates Non-Genomic Effects of Estrogen.

Pupo M, Maggiolini M, Musti AM.

Methods Mol Biol. 2016;1366:471-488. doi: 10.1007/978-1-4939-3127-9_37.

PMID:
26585158
7.

Cytoplasmic GPER translocation in cancer-associated fibroblasts mediates cAMP/PKA/CREB/glycolytic axis to confer tumor cells with multidrug resistance.

Yu T, Yang G, Hou Y, Tang X, Wu C, Wu XA, Guo L, Zhu Q, Luo H, Du YE, Wen S, Xu L, Yin J, Tu G, Liu M.

Oncogene. 2017 Apr;36(15):2131-2145. doi: 10.1038/onc.2016.370. Epub 2016 Oct 10.

PMID:
27721408
8.

SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer.

Santolla MF, Avino S, Pellegrino M, De Francesco EM, De Marco P, Lappano R, Vivacqua A, Cirillo F, Rigiracciolo DC, Scarpelli A, Abonante S, Maggiolini M.

Cell Death Dis. 2015 Jul 30;6:e1834. doi: 10.1038/cddis.2015.201.

9.

Bisphenol A induces gene expression changes and proliferative effects through GPER in breast cancer cells and cancer-associated fibroblasts.

Pupo M, Pisano A, Lappano R, Santolla MF, De Francesco EM, Abonante S, Rosano C, Maggiolini M.

Environ Health Perspect. 2012 Aug;120(8):1177-82. doi: 10.1289/ehp.1104526. Epub 2012 May 2.

10.

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts.

Madeo A, Maggiolini M.

Cancer Res. 2010 Jul 15;70(14):6036-46. doi: 10.1158/0008-5472.CAN-10-0408. Epub 2010 Jun 15.

11.

Insulin-like growth factor-I regulates GPER expression and function in cancer cells.

De Marco P, Bartella V, Vivacqua A, Lappano R, Santolla MF, Morcavallo A, Pezzi V, Belfiore A, Maggiolini M.

Oncogene. 2013 Feb 7;32(6):678-88. doi: 10.1038/onc.2012.97. Epub 2012 Mar 19.

PMID:
22430216
12.

GPER-mediated proliferation and estradiol production in breast cancer-associated fibroblasts.

Luo H, Yang G, Yu T, Luo S, Wu C, Sun Y, Liu M, Tu G.

Endocr Relat Cancer. 2014 Mar 7;21(2):355-69. doi: 10.1530/ERC-13-0237. Print 2014 Apr.

13.

Estrogenic gper signaling regulates mir144 expression in cancer cells and cancer-associated fibroblasts (cafs).

Vivacqua A, De Marco P, Santolla MF, Cirillo F, Pellegrino M, Panno ML, Abonante S, Maggiolini M.

Oncotarget. 2015 Jun 30;6(18):16573-87.

14.

G protein-coupled estrogen receptor mediates the up-regulation of fatty acid synthase induced by 17β-estradiol in cancer cells and cancer-associated fibroblasts.

Santolla MF, Lappano R, De Marco P, Pupo M, Vivacqua A, Sisci D, Abonante S, Iacopetta D, Cappello AR, Dolce V, Maggiolini M.

J Biol Chem. 2012 Dec 21;287(52):43234-45. doi: 10.1074/jbc.M112.417303. Epub 2012 Nov 7.

15.

Two novel GPER agonists induce gene expression changes and growth effects in cancer cells.

Lappano R, Rosano C, Santolla MF, Pupo M, De Francesco EM, De Marco P, Ponassi M, Spallarossa A, Ranise A, Maggiolini M.

Curr Cancer Drug Targets. 2012 Jun;12(5):531-42.

PMID:
22414008
16.

GPER mediates enhanced cell viability and motility via non-genomic signaling induced by 17β-estradiol in triple-negative breast cancer cells.

Yu T, Liu M, Luo H, Wu C, Tang X, Tang S, Hu P, Yan Y, Wang Z, Tu G.

J Steroid Biochem Mol Biol. 2014 Sep;143:392-403. doi: 10.1016/j.jsbmb.2014.05.003. Epub 2014 May 27.

PMID:
24874276
17.

Tamoxifen through GPER upregulates aromatase expression: a novel mechanism sustaining tamoxifen-resistant breast cancer cell growth.

Catalano S, Giordano C, Panza S, Chemi F, Bonofiglio D, Lanzino M, Rizza P, Romeo F, Fuqua SA, Maggiolini M, Andò S, Barone I.

Breast Cancer Res Treat. 2014 Jul;146(2):273-85. doi: 10.1007/s10549-014-3017-4. Epub 2014 Jun 14.

PMID:
24928526
18.

GPER mediates activation of HIF1α/VEGF signaling by estrogens.

De Francesco EM, Pellegrino M, Santolla MF, Lappano R, Ricchio E, Abonante S, Maggiolini M.

Cancer Res. 2014 Aug 1;74(15):4053-64. doi: 10.1158/0008-5472.CAN-13-3590. Epub 2014 Jun 3.

19.

GPER mediated estradiol reduces miR-148a to promote HLA-G expression in breast cancer.

Tao S, He H, Chen Q, Yue W.

Biochem Biophys Res Commun. 2014 Aug 15;451(1):74-8. doi: 10.1016/j.bbrc.2014.07.073. Epub 2014 Jul 22.

PMID:
25063027
20.

Niacin activates the G protein estrogen receptor (GPER)-mediated signalling.

Santolla MF, De Francesco EM, Lappano R, Rosano C, Abonante S, Maggiolini M.

Cell Signal. 2014 Jul;26(7):1466-75. doi: 10.1016/j.cellsig.2014.03.011. Epub 2014 Mar 21.

PMID:
24662263

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