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Tumor-infiltrating PD1-Positive Lymphocytes and FoxP3-Positive Regulatory T Cells Predict Distant Metastatic Relapse and Survival of Clear Cell Renal Cell Carcinoma.

Kang MJ, Kim KM, Bae JS, Park HS, Lee H, Chung MJ, Moon WS, Lee DG, Jang KY.

Transl Oncol. 2013 Jun 1;6(3):282-9. Print 2013 Jun.


Tumor infiltrating PD1-positive lymphocytes and the expression of PD-L1 predict poor prognosis of soft tissue sarcomas.

Kim JR, Moon YJ, Kwon KS, Bae JS, Wagle S, Kim KM, Park HS, Lee H, Moon WS, Chung MJ, Kang MJ, Jang KY.

PLoS One. 2013 Dec 11;8(12):e82870. doi: 10.1371/journal.pone.0082870. eCollection 2013 Dec 11.


Tumor-infiltrating Foxp3+ regulatory T cells are correlated with cyclooxygenase-2 expression and are associated with recurrence in resected non-small cell lung cancer.

Shimizu K, Nakata M, Hirami Y, Yukawa T, Maeda A, Tanemoto K.

J Thorac Oncol. 2010 May;5(5):585-90. doi: 10.1097/JTO.0b013e3181d60fd7.


Higher intratumoral infiltrated Foxp3+ Treg numbers and Foxp3+/CD8+ ratio are associated with adverse prognosis in resectable gastric cancer.

Shen Z, Zhou S, Wang Y, Li RL, Zhong C, Liang C, Sun Y.

J Cancer Res Clin Oncol. 2010 Oct;136(10):1585-95. doi: 10.1007/s00432-010-0816-9. Epub 2010 Mar 11.


Intratumoral forkhead box P3-positive regulatory T cells predict poor survival in cyclooxygenase-2-positive uveal melanoma.

Mougiakakos D, Johansson CC, Trocme E, All-Ericsson C, Economou MA, Larsson O, Seregard S, Kiessling R.

Cancer. 2010 May 1;116(9):2224-33. doi: 10.1002/cncr.24999.


Prognostic value of tumor-infiltrating lymphocytes in Epstein-Barr virus-associated gastric cancer.

Kang BW, Seo AN, Yoon S, Bae HI, Jeon SW, Kwon OK, Chung HY, Yu W, Kang H, Kim JG.

Ann Oncol. 2016 Mar;27(3):494-501. doi: 10.1093/annonc/mdv610. Epub 2015 Dec 16.


The Association Between PD-L1 Expression and the Clinical Outcomes to Vascular Endothelial Growth Factor-Targeted Therapy in Patients With Metastatic Clear Cell Renal Cell Carcinoma.

Shin SJ, Jeon YK, Cho YM, Lee JL, Chung DH, Park JY, Go H.

Oncologist. 2015 Nov;20(11):1253-60. doi: 10.1634/theoncologist.2015-0151. Epub 2015 Sep 30.


Increased intratumoral FOXP3-positive regulatory immune cells during interleukin-2 treatment in metastatic renal cell carcinoma.

Jensen HK, Donskov F, Nordsmark M, Marcussen N, von der Maase H.

Clin Cancer Res. 2009 Feb 1;15(3):1052-8. doi: 10.1158/1078-0432.CCR-08-1296.


Regulatory T cell infiltration predicts outcome following resection of colorectal cancer liver metastases.

Katz SC, Bamboat ZM, Maker AV, Shia J, Pillarisetty VG, Yopp AC, Hedvat CV, Gonen M, Jarnagin WR, Fong Y, D'Angelica MI, DeMatteo RP.

Ann Surg Oncol. 2013 Mar;20(3):946-55. doi: 10.1245/s10434-012-2668-9. Epub 2012 Sep 26.


Acetylation status of P53 and the expression of DBC1, SIRT1, and androgen receptor are associated with survival in clear cell renal cell carcinoma patients.

Noh SJ, Kang MJ, Kim KM, Bae JS, Park HS, Moon WS, Chung MJ, Lee H, Lee DG, Jang KY.

Pathology. 2013 Oct;45(6):574-80. doi: 10.1097/PAT.0b013e3283652c7a.


Type II papillary histology predicts poor outcome in patients with renal cell carcinoma and vena cava thrombus.

Kim KH, You D, Jeong IG, Kwon TW, Cho YM, Hong JH, Ahn H, Kim CS.

BJU Int. 2012 Dec;110(11 Pt B):E673-8. doi: 10.1111/j.1464-410X.2012.11498.x. Epub 2012 Sep 14.


Prognostic potential of FOXP3 expression in non-small cell lung cancer cells combined with tumor-infiltrating regulatory T cells.

Tao H, Mimura Y, Aoe K, Kobayashi S, Yamamoto H, Matsuda E, Okabe K, Matsumoto T, Sugi K, Ueoka H.

Lung Cancer. 2012 Jan;75(1):95-101. doi: 10.1016/j.lungcan.2011.06.002. Epub 2011 Jun 29.


CD8⁺ cytotoxic T cell and FOXP3⁺ regulatory T cell infiltration in relation to breast cancer survival and molecular subtypes.

Liu F, Lang R, Zhao J, Zhang X, Pringle GA, Fan Y, Yin D, Gu F, Yao Z, Fu L.

Breast Cancer Res Treat. 2011 Nov;130(2):645-55. doi: 10.1007/s10549-011-1647-3. Epub 2011 Jun 30.


A comparative study of metastatic renal cell carcinoma with correlation to subtype and primary tumor.

Mai KT, Landry DC, Robertson SJ, Commons AS, Burns BF, Thijssen A, Collins J.

Pathol Res Pract. 2001;197(10):671-5.


Pathobiology and prognosis of chromophobe renal cell carcinoma.

Klatte T, Han KR, Said JW, Böhm M, Allhoff EP, Kabbinavar FF, Belldegrun AS, Pantuck AJ.

Urol Oncol. 2008 Nov-Dec;26(6):604-9. doi: 10.1016/j.urolonc.2007.07.015. Epub 2008 Jan 14.


Prediction of recurrence and survival in hepatocellular carcinoma based on two Cox models mainly determined by FoxP3+ regulatory T cells.

Lin SZ, Chen KJ, Xu ZY, Chen H, Zhou L, Xie HY, Zheng SS.

Cancer Prev Res (Phila). 2013 Jun;6(6):594-602. doi: 10.1158/1940-6207.CAPR-12-0379. Epub 2013 Apr 18.


Prognostic significance of tumor-infiltrating T-lymphocytes in primary and metastatic lesions of advanced stage ovarian cancer.

Leffers N, Gooden MJ, de Jong RA, Hoogeboom BN, ten Hoor KA, Hollema H, Boezen HM, van der Zee AG, Daemen T, Nijman HW.

Cancer Immunol Immunother. 2009 Mar;58(3):449-59. doi: 10.1007/s00262-008-0583-5. Epub 2008 Sep 13.


Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection.

Gao Q, Qiu SJ, Fan J, Zhou J, Wang XY, Xiao YS, Xu Y, Li YW, Tang ZY.

J Clin Oncol. 2007 Jun 20;25(18):2586-93.


Alteration in regulatory T cells and programmed cell death 1-expressing regulatory T cells in active generalized vitiligo and their clinical correlation.

Tembhre MK, Parihar AS, Sharma VK, Sharma A, Chattopadhyay P, Gupta S.

Br J Dermatol. 2015 Apr;172(4):940-50. doi: 10.1111/bjd.13511. Epub 2015 Feb 27.


FOXO1 and TCF7L2 genes involved in metastasis and poor prognosis in clear cell renal cell carcinoma.

Kojima T, Shimazui T, Horie R, Hinotsu S, Oikawa T, Kawai K, Suzuki H, Meno K, Akaza H, Uchida K.

Genes Chromosomes Cancer. 2010 Apr;49(4):379-89. doi: 10.1002/gcc.20750.


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