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Items: 1 to 20 of 101

1.

Suppression of colon carcinogenesis by targeting Notch signaling.

Miyamoto S, Nakanishi M, Rosenberg DW.

Carcinogenesis. 2013 Oct;34(10):2415-23. doi: 10.1093/carcin/bgt191. Epub 2013 Jun 1.

2.

Notch inhibits expression of the Krüppel-like factor 4 tumor suppressor in the intestinal epithelium.

Ghaleb AM, Aggarwal G, Bialkowska AB, Nandan MO, Yang VW.

Mol Cancer Res. 2008 Dec;6(12):1920-7. doi: 10.1158/1541-7786.MCR-08-0224.

3.

Effects of N-[N-(3, 5-difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester (DAPT) on cell proliferation and apoptosis in Ishikawa endometrial cancer cells.

Mori M, Miyamoto T, Yakushiji H, Ohno S, Miyake Y, Sakaguchi T, Hattori M, Hongo A, Nakaizumi A, Ueda M, Ohno E.

Hum Cell. 2012 Mar;25(1):9-15. doi: 10.1007/s13577-011-0038-8. Epub 2011 Dec 22.

PMID:
22189483
4.

Three Pathways of Colonic Carcinogenesis in Rats.

Rubio CA.

Anticancer Res. 2017 Jan;37(1):15-20. Review.

PMID:
28011469
5.

Atonal homolog 1 is required for growth and differentiation effects of notch/gamma-secretase inhibitors on normal and cancerous intestinal epithelial cells.

Kazanjian A, Noah T, Brown D, Burkart J, Shroyer NF.

Gastroenterology. 2010 Sep;139(3):918-28, 928.e1-6. doi: 10.1053/j.gastro.2010.05.081. Epub 2010 Jun 2.

6.

Targeting Notch signaling by γ-secretase inhibitor I enhances the cytotoxic effect of 5-FU in gastric cancer.

Lee HW, Kim SJ, Choi IJ, Song J, Chun KH.

Clin Exp Metastasis. 2015 Aug;32(6):593-603. doi: 10.1007/s10585-015-9730-5. Epub 2015 Jul 2.

PMID:
26134677
7.
8.

gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity.

Meng RD, Shelton CC, Li YM, Qin LX, Notterman D, Paty PB, Schwartz GK.

Cancer Res. 2009 Jan 15;69(2):573-82. doi: 10.1158/0008-5472.CAN-08-2088.

9.

In vivo manifestation of Notch related phenotypes in zebrafish treated with Alzheimer's amyloid reducing gamma-secretase inhibitors.

Yang T, Arslanova D, Xu X, Li YM, Xia W.

J Neurochem. 2010 Jun;113(5):1200-9. doi: 10.1111/j.1471-4159.2010.06681.x. Epub 2010 Mar 12.

12.

The Heparanase Inhibitor PG545 Attenuates Colon Cancer Initiation and Growth, Associating with Increased p21 Expression.

Singh P, Blatt A, Feld S, Zohar Y, Saadi E, Barki-Harrington L, Hammond E, Ilan N, Vlodavsky I, Chowers Y, Half E.

Neoplasia. 2017 Mar;19(3):175-184. doi: 10.1016/j.neo.2016.12.001. Epub 2017 Jan 29.

13.

Notch signaling contributes to lung cancer clonogenic capacity in vitro but may be circumvented in tumorigenesis in vivo.

Osanyingbemi-Obidi J, Dobromilskaya I, Illei PB, Hann CL, Rudin CM.

Mol Cancer Res. 2011 Dec;9(12):1746-54. doi: 10.1158/1541-7786.MCR-11-0286. Epub 2011 Oct 12.

14.

5,5'-Dibromo-bis(3'-indolyl)methane induces Kruppel-like factor 4 and p21 in colon cancer cells.

Cho SD, Chintharlapalli S, Abdelrahim M, Papineni S, Liu S, Guo J, Lei P, Abudayyeh A, Safe S.

Mol Cancer Ther. 2008 Jul;7(7):2109-20. doi: 10.1158/1535-7163.MCT-07-2311.

15.

FXR silencing in human colon cancer by DNA methylation and KRAS signaling.

Bailey AM, Zhan L, Maru D, Shureiqi I, Pickering CR, Kiriakova G, Izzo J, He N, Wei C, Baladandayuthapani V, Liang H, Kopetz S, Powis G, Guo GL.

Am J Physiol Gastrointest Liver Physiol. 2014 Jan 1;306(1):G48-58. doi: 10.1152/ajpgi.00234.2013. Epub 2013 Oct 31. Erratum in: Am J Physiol Gastrointest Liver Physiol. 2014 Feb 15;306(4):G357.

16.

Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family.

Suliman MA, Zhang Z, Na H, Ribeiro AL, Zhang Y, Niang B, Hamid AS, Zhang H, Xu L, Zuo Y.

Int J Mol Med. 2016 Sep;38(3):776-84. doi: 10.3892/ijmm.2016.2689. Epub 2016 Jul 22.

17.

Activation of Notch signaling in tumorigenesis of experimental pancreatic cancer induced by dimethylbenzanthracene in mice.

Kimura K, Satoh K, Kanno A, Hamada S, Hirota M, Endoh M, Masamune A, Shimosegawa T.

Cancer Sci. 2007 Feb;98(2):155-62.

PMID:
17297654
18.

Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.

Konishi J, Kawaguchi KS, Vo H, Haruki N, Gonzalez A, Carbone DP, Dang TP.

Cancer Res. 2007 Sep 1;67(17):8051-7.

19.

Inhibition of the Notch-Hey1 axis blocks embryonal rhabdomyosarcoma tumorigenesis.

Belyea BC, Naini S, Bentley RC, Linardic CM.

Clin Cancer Res. 2011 Dec 1;17(23):7324-36. doi: 10.1158/1078-0432.CCR-11-1004. Epub 2011 Sep 23.

20.

Blockade of Notch signaling ameliorates murine collagen-induced arthritis via suppressing Th1 and Th17 cell responses.

Jiao Z, Wang W, Hua S, Liu M, Wang H, Wang X, Chen Y, Xu H, Lu L.

Am J Pathol. 2014 Apr;184(4):1085-93. doi: 10.1016/j.ajpath.2013.12.010. Epub 2014 Feb 1.

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