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Items: 1 to 20 of 72

1.

The active form of goat insulin-like peptide 3 (INSL3) is a single-chain structure comprising three domains B-C-A, constitutively expressed and secreted by testicular Leydig cells.

Siqin , Minagawa I, Okuno M, Yamada K, Sugawara Y, Nagura Y, Hamano KI, Park EY, Sasada H, Kohsaka T.

Biol Chem. 2013 May 17. pii: /j/bchm.just-accepted/hsz-2013-0357/hsz-2013-0357.xml. doi: 10.1515/hsz-2013-0357. [Epub ahead of print]

PMID:
23729566
2.

The active form of goat insulin-like peptide 3 (INSL3) is a single-chain structure comprising three domains B-C-A, constitutively expressed and secreted by testicular Leydig cells.

Siqin, Minagawa I, Okuno M, Yamada K, Sugawara Y, Nagura Y, Hamano K, Park EY, Sasada H, Kohsaka T.

Biol Chem. 2013 Sep;394(9):1181-94. doi: 10.1515/hsz-2012-0357.

PMID:
23934571
3.

Relaxin-like factor (RLF)/insulin-like peptide 3 (INSL3) is secreted from testicular Leydig cells as a monomeric protein comprising three domains B-C-A with full biological activity in boars.

Minagawa I, Fukuda M, Ishige H, Kohriki H, Shibata M, Park EY, Kawarasaki T, Kohsaka T.

Biochem J. 2012 Jan 1;441(1):265-73. doi: 10.1042/BJ20111107.

4.

Partial cDNA sequence of a relaxin-like factor (RLF) receptor, LGR8 and possible existence of the RLF ligand-receptor system in goat testes.

Siqin, Nakai M, Hagi T, Kato S, Pitia AM, Kotani M, Odanaka Y, Sugawara Y, Hamano K, Yogo K, Nagura Y, Fujita M, Sasada H, Sato E, Kohsaka T.

Anim Sci J. 2010 Dec;81(6):681-6. doi: 10.1111/j.1740-0929.2010.00801.x. Epub 2010 Oct 29.

PMID:
21108688
5.

Recombinant expression of an insulin-like peptide 3 (INSL3) precursor and its enzymatic conversion to mature human INSL3.

Luo X, Bathgate RA, Liu YL, Shao XX, Wade JD, Guo ZY.

FEBS J. 2009 Sep;276(18):5203-11. doi: 10.1111/j.1742-4658.2009.07216.x. Epub 2009 Aug 10.

6.

Design, synthesis and pharmacological evaluation of cyclic mimetics of the insulin-like peptide 3 (INSL3) B-chain.

Shabanpoor F, Bathgate RA, Hossain MA, Giannakis E, Wade JD, Hughes RA.

J Pept Sci. 2007 Feb;13(2):113-20.

PMID:
17120268
7.

Reproductive biology of the relaxin-like factor (RLF/INSL3).

Ivell R, Bathgate RA.

Biol Reprod. 2002 Sep;67(3):699-705. Review.

PMID:
12193374
8.

Dynamics of insulin-like factor 3 and its receptor expression in boar testes.

Minagawa I, Sagata D, Pitia AM, Kohriki H, Shibata M, Sasada H, Hasegawa Y, Kohsaka T.

J Endocrinol. 2014 Jan 30;220(3):247-61. doi: 10.1530/JOE-13-0430. Print 2014 Mar.

9.

Insulin-like factor 3: where are we now?

Ivell R, Hartung S, Anand-Ivell R.

Ann N Y Acad Sci. 2005 May;1041:486-96. Review.

PMID:
15956750
10.

Relaxin gene family in teleosts: phylogeny, syntenic mapping, selective constraint, and expression analysis.

Good-Avila SV, Yegorov S, Harron S, Bogerd J, Glen P, Ozon J, Wilson BC.

BMC Evol Biol. 2009 Dec 16;9:293. doi: 10.1186/1471-2148-9-293.

11.

Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3.

Rosengren KJ, Zhang S, Lin F, Daly NL, Scott DJ, Hughes RA, Bathgate RA, Craik DJ, Wade JD.

J Biol Chem. 2006 Sep 22;281(38):28287-95. Epub 2006 Jul 25.

12.

Design and development of analogues of dimers of insulin-like peptide 3 B-chain as high-affinity antagonists of the RXFP2 receptor.

Shabanpoor F, Zhang S, Hughes RA, Hossain MA, Layfield S, Ferraro T, Bathgate RA, Separovic F, Wade JD.

Biopolymers. 2011;96(1):81-7. doi: 10.1002/bip.21484.

PMID:
20560146
13.

Constitutive regulation of the Insl3 gene in rat Leydig cells.

Sadeghian H, Anand-Ivell R, Balvers M, Relan V, Ivell R.

Mol Cell Endocrinol. 2005 Sep 28;241(1-2):10-20.

PMID:
16006031
14.

Expression of insulin-like factor 3 hormone-receptor system in the reproductive organs of male goats.

Pitia AM, Minagawa I, Uera N, Hamano K, Sugawara Y, Nagura Y, Hasegawa Y, Oyamada T, Sasada H, Kohsaka T.

Cell Tissue Res. 2015 Nov;362(2):407-20. doi: 10.1007/s00441-015-2206-8. Epub 2015 May 28.

PMID:
26017634
15.

INSL3 ligand-receptor system in the equine testis.

Klonisch T, Steger K, Kehlen A, Allen WR, Froehlich C, Kauffold J, Bergmann M, Hombach-Klonisch S.

Biol Reprod. 2003 Jun;68(6):1975-81. Epub 2003 Jan 8.

PMID:
12606415
16.

Chemical synthesis and biological activity of rat INSL3.

Smith KJ, Wade JD, Claasz AA, Otvos L Jr, Temelcos C, Kubota Y, Hutson JM, Tregear GW, Bathgate RA.

J Pept Sci. 2001 Sep;7(9):495-501.

PMID:
11587188
17.

INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent.

Kumagai J, Hsu SY, Matsumi H, Roh JS, Fu P, Wade JD, Bathgate RA, Hsueh AJ.

J Biol Chem. 2002 Aug 30;277(35):31283-6. Epub 2002 Jul 11.

18.

The novel hormone INSL3 is expressed in human testicular Leydig cell tumors: a clinical and immunohistochemical study.

Rossato M, Tavolini IM, Calcagno A, Gardiman M, Dal Moro F, Artibani W.

Urol Oncol. 2011 Jan-Feb;29(1):33-7. doi: 10.1016/j.urolonc.2008.10.015. Epub 2008 Dec 25.

PMID:
19110449
19.

The orphan nuclear receptor NR4A1 regulates insulin-like 3 gene transcription in Leydig cells.

Robert NM, Martin LJ, Tremblay JJ.

Biol Reprod. 2006 Feb;74(2):322-30. Epub 2005 Oct 19.

PMID:
16237153
20.

Analogs of insulin-like peptide 3 (INSL3) B-chain are LGR8 antagonists in vitro and in vivo.

Del Borgo MP, Hughes RA, Bathgate RA, Lin F, Kawamura K, Wade JD.

J Biol Chem. 2006 May 12;281(19):13068-74. Epub 2006 Mar 17.

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