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Items: 1 to 20 of 81


Picornavirus uncoating intermediate captured in atomic detail.

Ren J, Wang X, Hu Z, Gao Q, Sun Y, Li X, Porta C, Walter TS, Gilbert RJ, Zhao Y, Axford D, Williams M, McAuley K, Rowlands DJ, Yin W, Wang J, Stuart DI, Rao Z, Fry EE.

Nat Commun. 2013;4:1929. doi: 10.1038/ncomms2889.


Uncoating of common cold virus is preceded by RNA switching as determined by X-ray and cryo-EM analyses of the subviral A-particle.

Pickl-Herk A, Luque D, Vives-Adrián L, Querol-Audí J, Garriga D, Trus BL, Verdaguer N, Blaas D, Castón JR.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20063-8. doi: 10.1073/pnas.1312128110. Epub 2013 Nov 25.


Limits of structural plasticity in a picornavirus capsid revealed by a massively expanded equine rhinitis A virus particle.

Bakker SE, Groppelli E, Pearson AR, Stockley PG, Rowlands DJ, Ranson NA.

J Virol. 2014 Jun;88(11):6093-9. doi: 10.1128/JVI.01979-13. Epub 2014 Mar 19.



Tuthill TJ, Groppelli E, Hogle JM, Rowlands DJ.

Curr Top Microbiol Immunol. 2010;343:43-89. doi: 10.1007/82_2010_37.


Structural and functional analysis of coxsackievirus A9 integrin αvβ6 binding and uncoating.

Shakeel S, Seitsonen JJ, Kajander T, Laurinmäki P, Hyypiä T, Susi P, Butcher SJ.

J Virol. 2013 Apr;87(7):3943-51. doi: 10.1128/JVI.02989-12. Epub 2013 Jan 30.


The enterovirus 71 A-particle forms a gateway to allow genome release: a cryoEM study of picornavirus uncoating.

Shingler KL, Yoder JL, Carnegie MS, Ashley RE, Makhov AM, Conway JF, Hafenstein S.

PLoS Pathog. 2013 Mar;9(3):e1003240. doi: 10.1371/journal.ppat.1003240. Epub 2013 Mar 21. Erratum in: PLoS Pathog. 2013 Sep;9(9). doi: 10.1371/annotation/e92d19e0-996a-4bfa-afdd-20dce770ed75.


Raman spectroscopic signatures of echovirus 1 uncoating.

Ruokola P, Dadu E, Kazmertsuk A, Häkkänen H, Marjomäki V, Ihalainen JA.

J Virol. 2014 Aug;88(15):8504-13. doi: 10.1128/JVI.03398-13. Epub 2014 May 21.


Structure and Genome Release Mechanism of the Human Cardiovirus Saffold Virus 3.

Mullapudi E, Nováček J, Pálková L, Kulich P, Lindberg AM, van Kuppeveld FJ, Plevka P.

J Virol. 2016 Aug 12;90(17):7628-39. doi: 10.1128/JVI.00746-16. Print 2016 Sep 1.


Viral uncoating is directional: exit of the genomic RNA in a common cold virus starts with the poly-(A) tail at the 3'-end.

Harutyunyan S, Kumar M, Sedivy A, Subirats X, Kowalski H, Köhler G, Blaas D.

PLoS Pathog. 2013;9(4):e1003270. doi: 10.1371/journal.ppat.1003270. Epub 2013 Apr 4.


The refined structure of human rhinovirus 16 at 2.15 A resolution: implications for the viral life cycle.

Hadfield AT, Lee Wm, Zhao R, Oliveira MA, Minor I, Rueckert RR, Rossmann MG.

Structure. 1997 Mar 15;5(3):427-41.


Implications for viral uncoating from the structure of bovine enterovirus.

Smyth M, Tate J, Hoey E, Lyons C, Martin S, Stuart D.

Nat Struct Biol. 1995 Mar;2(3):224-31.


Picornavirus entry.

Bergelson JM, Coyne CB.

Adv Exp Med Biol. 2013;790:24-41. doi: 10.1007/978-1-4614-7651-1_2. Review.


Molecular mechanism of SCARB2-mediated attachment and uncoating of EV71.

Dang M, Wang X, Wang Q, Wang Y, Lin J, Sun Y, Li X, Zhang L, Lou Z, Wang J, Rao Z.

Protein Cell. 2014 Sep;5(9):692-703. doi: 10.1007/s13238-014-0087-3. Epub 2014 Jul 2.


Hepatitis A virus and the origins of picornaviruses.

Wang X, Ren J, Gao Q, Hu Z, Sun Y, Li X, Rowlands DJ, Yin W, Wang J, Stuart DI, Rao Z, Fry EE.

Nature. 2015 Jan 1;517(7532):85-88. doi: 10.1038/nature13806. Epub 2014 Oct 19.


A Novel Open and Infectious Form of Echovirus 1.

Myllynen M, Kazmertsuk A, Marjomäki V.

J Virol. 2016 Jul 11;90(15):6759-70. doi: 10.1128/JVI.00342-16. Print 2016 Aug 1.


The crystal structure of cricket paralysis virus: the first view of a new virus family.

Tate J, Liljas L, Scotti P, Christian P, Lin T, Johnson JE.

Nat Struct Biol. 1999 Aug;6(8):765-74.


Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity.

Ren J, Wang X, Zhu L, Hu Z, Gao Q, Yang P, Li X, Wang J, Shen X, Fry EE, Rao Z, Stuart DI.

J Virol. 2015 Oct;89(20):10500-11. doi: 10.1128/JVI.01102-15. Epub 2015 Aug 12.


Low temperature and pressure stability of picornaviruses: implications for virus uncoating.

Oliveira AC, Ishimaru D, Gonçalves RB, Smith TJ, Mason P, Sá-Carvalho D, Silva JL.

Biophys J. 1999 Mar;76(3):1270-9.


Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes.

Groppelli E, Levy HC, Sun E, Strauss M, Nicol C, Gold S, Zhuang X, Tuthill TJ, Hogle JM, Rowlands DJ.

PLoS Pathog. 2017 Feb 6;13(2):e1006197. doi: 10.1371/journal.ppat.1006197. eCollection 2017 Feb.

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