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Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation.

Rancourt RC, Veress LA, Ahmad A, Hendry-Hofer TB, Rioux JS, Garlick RB, White CW.

Toxicol Appl Pharmacol. 2013 Oct 1;272(1):86-95. doi: 10.1016/j.taap.2013.05.020. Epub 2013 May 30.


Antifibrinolytic mechanisms in acute airway injury after sulfur mustard analog inhalation.

Rancourt RC, Ahmad A, Veress LA, Rioux JS, Garlick RB, White CW.

Am J Respir Cell Mol Biol. 2014 Oct;51(4):559-67. doi: 10.1165/rcmb.2014-0012OC.


Airway obstruction due to bronchial vascular injury after sulfur mustard analog inhalation.

Veress LA, O'Neill HC, Hendry-Hofer TB, Loader JE, Rancourt RC, White CW.

Am J Respir Crit Care Med. 2010 Dec 1;182(11):1352-61. doi: 10.1164/rccm.200910-1618OC. Epub 2010 Jul 16.


Airway tissue plasminogen activator prevents acute mortality due to lethal sulfur mustard inhalation.

Veress LA, Anderson DR, Hendry-Hofer TB, Houin PR, Rioux JS, Garlick RB, Loader JE, Paradiso DC, Smith RW, Rancourt RC, Holmes WW, White CW.

Toxicol Sci. 2015 Jan;143(1):178-84. doi: 10.1093/toxsci/kfu225. Epub 2014 Oct 20.


Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog.

Houin PR, Veress LA, Rancourt RC, Hendry-Hofer TB, Loader JE, Rioux JS, Garlick RB, White CW.

Pediatr Pulmonol. 2015 Feb;50(2):118-26. doi: 10.1002/ppul.23043. Epub 2014 Apr 1.


Airway tissue factor-dependent coagulation activity in response to sulfur mustard analog 2-chloroethyl ethyl sulfide.

Rancourt RC, Veress LA, Guo X, Jones TN, Hendry-Hofer TB, White CW.

Am J Physiol Lung Cell Mol Physiol. 2012 Jan 1;302(1):L82-92. doi: 10.1152/ajplung.00306.2010. Epub 2011 Sep 30.


Tissue plasminogen activator prevents mortality from sulfur mustard analog-induced airway obstruction.

Veress LA, Hendry-Hofer TB, Loader JE, Rioux JS, Garlick RB, White CW.

Am J Respir Cell Mol Biol. 2013 Apr;48(4):439-47. doi: 10.1165/rcmb.2012-0177OC.


Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.

O'Neill HC, White CW, Veress LA, Hendry-Hofer TB, Loader JE, Min E, Huang J, Rancourt RC, Day BJ.

Free Radic Biol Med. 2010 May 1;48(9):1188-96. doi: 10.1016/j.freeradbiomed.2010.01.039. Epub 2010 Feb 4.


Postexposure application of Fas receptor small-interfering RNA to suppress sulfur mustard-induced apoptosis in human airway epithelial cells: implication for a therapeutic approach.

Keyser BM, Andres DK, Nealley E, Holmes WW, Benton B, Paradiso D, Appell A, Carpin C, Anderson DR, Smith WJ, Ray R.

J Pharmacol Exp Ther. 2013 Jan;344(1):308-16. doi: 10.1124/jpet.112.199935. Epub 2012 Nov 5.


N-acetyl-L-cysteine protects against inhaled sulfur mustard poisoning in the large swine.

Jugg B, Fairhall S, Smith A, Rutter S, Mann T, Perrott R, Jenner J, Salguero J, Shute J, Sciuto AM.

Clin Toxicol (Phila). 2013 May;51(4):216-24. doi: 10.3109/15563650.2013.780208. Epub 2013 Apr 2.


Sulfur mustard inhalation: mechanisms of injury, alteration of coagulation, and fibrinolytic therapy.

White CW, Rancourt RC, Veress LA.

Ann N Y Acad Sci. 2016 Aug;1378(1):87-95. doi: 10.1111/nyas.13130. Epub 2016 Jul 6. Review.


Induction of neuronal damage in guinea pig brain by intratracheal infusion of 2-chloroethyl ethyl sulfide, a mustard gas analog.

Gadsden-Gray J, Mukherjee S, Ogunkua O, Das SK.

J Biochem Mol Toxicol. 2012 Jan;26(1):23-30. doi: 10.1002/jbt.20409. Epub 2011 Sep 6.


Evaluation of protease inhibitors and an antioxidant for treatment of sulfur mustard-induced toxic lung injury.

Anderson DR, Taylor SL, Fetterer DP, Holmes WW.

Toxicology. 2009 Sep 1;263(1):41-6. doi: 10.1016/j.tox.2008.08.025. Epub 2008 Sep 21.


Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway.

Abel EL, Bubel JD, Simper MS, Powell L, McClellan SA, Andreeff M, MacLeod MC, DiGiovanni J.

Toxicol Appl Pharmacol. 2011 Sep 1;255(2):176-83. doi: 10.1016/j.taap.2011.06.012. Epub 2011 Jun 23.


Mechanism underlying acute lung injury due to sulfur mustard exposure in rats.

Xiaoji Z, Xiao M, Rui X, Haibo C, Chao Z, Chengjin L, Tao W, Wenjun G, Shengming Z.

Toxicol Ind Health. 2016 Aug;32(8):1345-1357. Epub 2014 Dec 23.


Role of reactive oxygen and nitrogen species in olfactory epithelial injury by the sulfur mustard analogue 2-chloroethyl ethyl sulfide.

O'Neill HC, Orlicky DJ, Hendry-Hofer TB, Loader JE, Day BJ, White CW.

Am J Respir Cell Mol Biol. 2011 Aug;45(2):323-31. doi: 10.1165/rcmb.2010-0214OC. Epub 2011 Jun 3.


Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin.

Jain AK, Tewari-Singh N, Gu M, Inturi S, White CW, Agarwal R.

Toxicol Lett. 2011 Sep 10;205(3):293-301. doi: 10.1016/j.toxlet.2011.06.019. Epub 2011 Jun 21.


Role of TNFR1 in lung injury and altered lung function induced by the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.

Sunil VR, Patel-Vayas K, Shen J, Gow AJ, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2011 Feb 1;250(3):245-55. doi: 10.1016/j.taap.2010.10.027. Epub 2010 Nov 9.


Attenuation of half sulfur mustard gas-induced acute lung injury in rats.

McClintock SD, Hoesel LM, Das SK, Till GO, Neff T, Kunkel RG, Smith MG, Ward PA.

J Appl Toxicol. 2006 Mar-Apr;26(2):126-31.

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