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SOD2 in mitochondrial dysfunction and neurodegeneration.

Flynn JM, Melov S.

Free Radic Biol Med. 2013 Sep;62:4-12. doi: 10.1016/j.freeradbiomed.2013.05.027. Epub 2013 May 29. Review.


Impaired spare respiratory capacity in cortical synaptosomes from Sod2 null mice.

Flynn JM, Choi SW, Day NU, Gerencser AA, Hubbard A, Melov S.

Free Radic Biol Med. 2011 Apr 1;50(7):866-73. doi: 10.1016/j.freeradbiomed.2010.12.030. Epub 2011 Jan 6.


Manganese superoxide dismutase and glutathione peroxidase-1 contribute to the rise and fall of mitochondrial reactive oxygen species which drive oncogenesis.

Ekoue DN, He C, Diamond AM, Bonini MG.

Biochim Biophys Acta Bioenerg. 2017 Aug;1858(8):628-632. doi: 10.1016/j.bbabio.2017.01.006. Epub 2017 Jan 11. Review.


Switch of Mitochondrial Superoxide Dismutase into a Prooxidant Peroxidase in Manganese-Deficient Cells and Mice.

Ganini D, Santos JH, Bonini MG, Mason RP.

Cell Chem Biol. 2018 Apr 19;25(4):413-425.e6. doi: 10.1016/j.chembiol.2018.01.007.


Mitochondrial oxidative stress and increased seizure susceptibility in Sod2(-/+) mice.

Liang LP, Patel M.

Free Radic Biol Med. 2004 Mar 1;36(5):542-54.


Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging.

Mansouri A, Muller FL, Liu Y, Ng R, Faulkner J, Hamilton M, Richardson A, Huang TT, Epstein CJ, Van Remmen H.

Mech Ageing Dev. 2006 Mar;127(3):298-306. Epub 2006 Jan 6.


Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders.

Sas K, Robotka H, Toldi J, Vécsei L.

J Neurol Sci. 2007 Jun 15;257(1-2):221-39. Epub 2007 Apr 25. Review.


SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness.

Friedman JS, Lopez MF, Fleming MD, Rivera A, Martin FM, Welsh ML, Boyd A, Doctrow SR, Burakoff SJ.

Blood. 2004 Oct 15;104(8):2565-73. Epub 2004 Jun 17.


Superoxide dismutase in redox biology: the roles of superoxide and hydrogen peroxide.

Buettner GR.

Anticancer Agents Med Chem. 2011 May 1;11(4):341-6. Review.


Redox Regulation of the Superoxide Dismutases SOD3 and SOD2 in the Pulmonary Circulation.

Hernandez-Saavedra D, Swain K, Tuder R, Petersen SV, Nozik-Grayck E.

Adv Exp Med Biol. 2017;967:57-70. doi: 10.1007/978-3-319-63245-2_5.


Mitochondrial respiratory chain dysfunction: implications in neurodegeneration.

Morán M, Moreno-Lastres D, Marín-Buera L, Arenas J, Martín MA, Ugalde C.

Free Radic Biol Med. 2012 Aug 1;53(3):595-609. doi: 10.1016/j.freeradbiomed.2012.05.009. Epub 2012 May 14. Review.


Overexpressing superoxide dismutase 2 induces a supernormal cardiac function by enhancing redox-dependent mitochondrial function and metabolic dilation.

Kang PT, Chen CL, Ohanyan V, Luther DJ, Meszaros JG, Chilian WM, Chen YR.

J Mol Cell Cardiol. 2015 Nov;88:14-28. doi: 10.1016/j.yjmcc.2015.09.001. Epub 2015 Sep 12.


SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin.

Pi H, Xu S, Reiter RJ, Guo P, Zhang L, Li Y, Li M, Cao Z, Tian L, Xie J, Zhang R, He M, Lu Y, Liu C, Duan W, Yu Z, Zhou Z.

Autophagy. 2015;11(7):1037-51. doi: 10.1080/15548627.2015.1052208.


Mitochondrial oxidative stress in aortic stiffening with age: the role of smooth muscle cell function.

Zhou RH, Vendrov AE, Tchivilev I, Niu XL, Molnar KC, Rojas M, Carter JD, Tong H, Stouffer GA, Madamanchi NR, Runge MS.

Arterioscler Thromb Vasc Biol. 2012 Mar;32(3):745-55. doi: 10.1161/ATVBAHA.111.243121. Epub 2011 Dec 22.


Enhanced catabolism of mitochondrial superoxide/hydrogen peroxide and aging in transgenic Drosophila.

Bayne AC, Mockett RJ, Orr WC, Sohal RS.

Biochem J. 2005 Oct 15;391(Pt 2):277-84.


Manganese superoxide dismutase inhibits neointima formation through attenuation of migration and proliferation of vascular smooth muscle cells.

Wang JN, Shi N, Chen SY.

Free Radic Biol Med. 2012 Jan 1;52(1):173-81. doi: 10.1016/j.freeradbiomed.2011.10.442. Epub 2011 Oct 24.


Teaching the fundamentals of electron transfer reactions in mitochondria and the production and detection of reactive oxygen species.

Mailloux RJ.

Redox Biol. 2015;4:381-98. doi: 10.1016/j.redox.2015.02.001. Epub 2015 Feb 7. Review.


Role of mitochondrial ROS in the brain: from physiology to neurodegeneration.

Angelova PR, Abramov AY.

FEBS Lett. 2018 Mar;592(5):692-702. doi: 10.1002/1873-3468.12964. Epub 2018 Jan 18. Review.


Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling.

Brand MD.

Free Radic Biol Med. 2016 Nov;100:14-31. doi: 10.1016/j.freeradbiomed.2016.04.001. Epub 2016 Apr 13. Review.


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