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Items: 1 to 20 of 217

1.

Astaxanthin inhibits NF-κB and Wnt/β-catenin signaling pathways via inactivation of Erk/MAPK and PI3K/Akt to induce intrinsic apoptosis in a hamster model of oral cancer.

Kavitha K, Kowshik J, Kishore TK, Baba AB, Nagini S.

Biochim Biophys Acta. 2013 Oct;1830(10):4433-44. doi: 10.1016/j.bbagen.2013.05.032. Epub 2013 May 29.

PMID:
23726989
2.

Ellagic acid coordinately attenuates Wnt/β-catenin and NF-κB signaling pathways to induce intrinsic apoptosis in an animal model of oral oncogenesis.

Anitha P, Priyadarsini RV, Kavitha K, Thiyagarajan P, Nagini S.

Eur J Nutr. 2013 Feb;52(1):75-84. doi: 10.1007/s00394-011-0288-y. Epub 2011 Dec 11.

PMID:
22160170
3.

Gedunin abrogates aldose reductase, PI3K/Akt/mToR, and NF-κB signaling pathways to inhibit angiogenesis in a hamster model of oral carcinogenesis.

Kishore T KK, Ganugula R, Gade DR, Reddy GB, Nagini S.

Tumour Biol. 2016 Feb;37(2):2083-93. doi: 10.1007/s13277-015-4003-0. Epub 2015 Sep 5.

PMID:
26342697
4.

Dietary chlorophyllin inhibits the canonical NF-κB signaling pathway and induces intrinsic apoptosis in a hamster model of oral oncogenesis.

Thiyagarajan P, Senthil Murugan R, Kavitha K, Anitha P, Prathiba D, Nagini S.

Food Chem Toxicol. 2012 Mar;50(3-4):867-76. doi: 10.1016/j.fct.2011.12.019. Epub 2011 Dec 21.

PMID:
22210229
5.

Nimbolide, a neem limonoid inhibits Phosphatidyl Inositol-3 Kinase to activate Glycogen Synthase Kinase-3β in a hamster model of oral oncogenesis.

Sophia J, Kiran Kishore T K, Kowshik J, Mishra R, Nagini S.

Sci Rep. 2016 Feb 23;6:22192. doi: 10.1038/srep22192.

6.

Wnt-11 signaling leads to down-regulation of the Wnt/beta-catenin, JNK/AP-1 and NF-kappaB pathways and promotes viability in the CHO-K1 cells.

Railo A, Nagy II, Kilpeläinen P, Vainio S.

Exp Cell Res. 2008 Aug 1;314(13):2389-99. doi: 10.1016/j.yexcr.2008.04.010. Epub 2008 May 3.

PMID:
18572162
7.

Aberrant activation of Wnt/β-catenin signaling pathway contributes to the sequential progression of DMBA-induced HBP carcinomas.

Vidya Priyadarsini R, Senthil Murugan R, Nagini S.

Oral Oncol. 2012 Jan;48(1):33-9. doi: 10.1016/j.oraloncology.2011.08.008. Epub 2011 Sep 15.

PMID:
21924667
8.

Nimbolide, a neem limonoid abrogates canonical NF-κB and Wnt signaling to induce caspase-dependent apoptosis in human hepatocarcinoma (HepG2) cells.

Kavitha K, Vidya Priyadarsini R, Anitha P, Ramalingam K, Sakthivel R, Purushothaman G, Singh AK, Karunagaran D, Nagini S.

Eur J Pharmacol. 2012 Apr 15;681(1-3):6-14. doi: 10.1016/j.ejphar.2012.01.024. Epub 2012 Jan 31.

PMID:
22327045
10.

The dietary phytochemical 3,3'-diindolylmethane induces G2/M arrest and apoptosis in oral squamous cell carcinoma by modulating Akt-NF-κB, MAPK, and p53 signaling.

Weng JR, Bai LY, Chiu CF, Wang YC, Tsai MH.

Chem Biol Interact. 2012 Feb 5;195(3):224-30. doi: 10.1016/j.cbi.2012.01.003. Epub 2012 Jan 24.

PMID:
22290291
11.

Blueberry inhibits invasion and angiogenesis in 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral squamous cell carcinogenesis in hamsters via suppression of TGF-β and NF-κB signaling pathways.

Baba AB, Kowshik J, Krishnaraj J, Sophia J, Dixit M, Nagini S.

J Nutr Biochem. 2016 Sep;35:37-47. doi: 10.1016/j.jnutbio.2016.06.002. Epub 2016 Jun 19.

PMID:
27371785
12.

Inhibition of GSK3 differentially modulates NF-kappaB, CREB, AP-1 and beta-catenin signaling in hepatocytes, but fails to promote TNF-alpha-induced apoptosis.

Götschel F, Kern C, Lang S, Sparna T, Markmann C, Schwager J, McNelly S, von Weizsäcker F, Laufer S, Hecht A, Merfort I.

Exp Cell Res. 2008 Apr 1;314(6):1351-66. doi: 10.1016/j.yexcr.2007.12.015. Epub 2007 Dec 31.

PMID:
18261723
13.

Morin impedes Yap nuclear translocation and fosters apoptosis through suppression of Wnt/β-catenin and NF-κB signaling in Mst1 overexpressed HepG2 cells.

Perumal N, Perumal M, Kannan A, Subramani K, Halagowder D, Sivasithamparam N.

Exp Cell Res. 2017 Jun 15;355(2):124-141. doi: 10.1016/j.yexcr.2017.03.062. Epub 2017 Mar 31.

PMID:
28366538
14.
15.

Cytomodulin-1, a synthetic peptide abrogates oncogenic signaling pathways to impede invasion and angiogenesis in the hamster cheek pouch carcinogenesis model.

Kavitha K, Kranthi Kiran Kishore T, Bhatnagar RS, Nagini S.

Biochimie. 2014 Jul;102:56-67. doi: 10.1016/j.biochi.2014.02.010. Epub 2014 Feb 27.

PMID:
24582832
16.

Astaxanthin inhibits JAK/STAT-3 signaling to abrogate cell proliferation, invasion and angiogenesis in a hamster model of oral cancer.

Kowshik J, Baba AB, Giri H, Deepak Reddy G, Dixit M, Nagini S.

PLoS One. 2014 Oct 8;9(10):e109114. doi: 10.1371/journal.pone.0109114. eCollection 2014.

18.

Quercetin inhibits migration and invasion of SAS human oral cancer cells through inhibition of NF-κB and matrix metalloproteinase-2/-9 signaling pathways.

Lai WW, Hsu SC, Chueh FS, Chen YY, Yang JS, Lin JP, Lien JC, Tsai CH, Chung JG.

Anticancer Res. 2013 May;33(5):1941-50.

PMID:
23645742
19.

Naphtho[1,2-b]furan-4,5-dione induces apoptosis of oral squamous cell carcinoma: involvement of EGF receptor/PI3K/Akt signaling pathway.

Chien CM, Lin KL, Su JC, Chuang PW, Tseng CH, Chen YL, Chang LS, Lin SR.

Eur J Pharmacol. 2010 Jun 25;636(1-3):52-8. doi: 10.1016/j.ejphar.2010.03.030. Epub 2010 Apr 2.

PMID:
20371243
20.

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