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Items: 1 to 20 of 98

1.

Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus.

Knight JS, Zhao W, Luo W, Subramanian V, O'Dell AA, Yalavarthi S, Hodgin JB, Eitzman DT, Thompson PR, Kaplan MJ.

J Clin Invest. 2013 Jul;123(7):2981-93. doi: 10.1172/JCI67390. Epub 2013 Jun 3.

2.

Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice.

Knight JS, Subramanian V, O'Dell AA, Yalavarthi S, Zhao W, Smith CK, Hodgin JB, Thompson PR, Kaplan MJ.

Ann Rheum Dis. 2015 Dec;74(12):2199-206. doi: 10.1136/annrheumdis-2014-205365. Epub 2014 Aug 7.

3.

Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis.

Knight JS, Luo W, O'Dell AA, Yalavarthi S, Zhao W, Subramanian V, Guo C, Grenn RC, Thompson PR, Eitzman DT, Kaplan MJ.

Circ Res. 2014 Mar 14;114(6):947-56. doi: 10.1161/CIRCRESAHA.114.303312. Epub 2014 Jan 14.

4.

At the Bedside: Neutrophil extracellular traps (NETs) as targets for biomarkers and therapies in autoimmune diseases.

Barnado A, Crofford LJ, Oates JC.

J Leukoc Biol. 2016 Feb;99(2):265-78. doi: 10.1189/jlb.5BT0615-234R. Epub 2015 Dec 11. Review.

5.

Cl-Amidine Prevents Histone 3 Citrullination and Neutrophil Extracellular Trap Formation, and Improves Survival in a Murine Sepsis Model.

Biron BM, Chung CS, O'Brien XM, Chen Y, Reichner JS, Ayala A.

J Innate Immun. 2017;9(1):22-32. doi: 10.1159/000448808. Epub 2016 Sep 14.

6.

Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2.

Carmona-Rivera C, Zhao W, Yalavarthi S, Kaplan MJ.

Ann Rheum Dis. 2015 Jul;74(7):1417-24. doi: 10.1136/annrheumdis-2013-204837. Epub 2014 Feb 25.

7.

Neutrophil extracellular trap-derived enzymes oxidize high-density lipoprotein: an additional proatherogenic mechanism in systemic lupus erythematosus.

Smith CK, Vivekanandan-Giri A, Tang C, Knight JS, Mathew A, Padilla RL, Gillespie BW, Carmona-Rivera C, Liu X, Subramanian V, Hasni S, Thompson PR, Heinecke JW, Saran R, Pennathur S, Kaplan MJ.

Arthritis Rheumatol. 2014 Sep;66(9):2532-2544. doi: 10.1002/art.38703.

8.

The role of neutrophils in the pathogenesis of systemic lupus erythematosus.

Smith CK, Kaplan MJ.

Curr Opin Rheumatol. 2015 Sep;27(5):448-53. doi: 10.1097/BOR.0000000000000197. Review.

PMID:
26125102
9.

Neutrophil Extracellular Trap Mitochondrial DNA and Its Autoantibody in Systemic Lupus Erythematosus and a Proof-of-Concept Trial of Metformin.

Wang H, Li T, Chen S, Gu Y, Ye S.

Arthritis Rheumatol. 2015 Dec;67(12):3190-200. doi: 10.1002/art.39296.

10.

Type I interferons modulate vascular function, repair, thrombosis, and plaque progression in murine models of lupus and atherosclerosis.

Thacker SG, Zhao W, Smith CK, Luo W, Wang H, Vivekanandan-Giri A, Rabquer BJ, Koch AE, Pennathur S, Davidson A, Eitzman DT, Kaplan MJ.

Arthritis Rheum. 2012 Sep;64(9):2975-85. doi: 10.1002/art.34504.

11.

Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor.

Chumanevich AA, Causey CP, Knuckley BA, Jones JE, Poudyal D, Chumanevich AP, Davis T, Matesic LE, Thompson PR, Hofseth LJ.

Am J Physiol Gastrointest Liver Physiol. 2011 Jun;300(6):G929-38. doi: 10.1152/ajpgi.00435.2010. Epub 2011 Mar 17.

12.

Ligation of signal inhibitory receptor on leukocytes-1 suppresses the release of neutrophil extracellular traps in systemic lupus erythematosus.

Van Avondt K, Fritsch-Stork R, Derksen RH, Meyaard L.

PLoS One. 2013 Oct 18;8(10):e78459. doi: 10.1371/journal.pone.0078459. eCollection 2013.

13.

Dispensability of APRIL to the development of systemic lupus erythematosus in NZM 2328 mice.

Jacob CO, Guo S, Jacob N, Pawar RD, Putterman C, Quinn WJ 3rd, Cancro MP, Migone TS, Stohl W.

Arthritis Rheum. 2012 May;64(5):1610-9. doi: 10.1002/art.33458.

14.
15.

The peroxisome proliferator-activated receptor gamma agonist pioglitazone improves cardiometabolic risk and renal inflammation in murine lupus.

Zhao W, Thacker SG, Hodgin JB, Zhang H, Wang JH, Park JL, Randolph A, Somers EC, Pennathur S, Kretzler M, Brosius FC 3rd, Kaplan MJ.

J Immunol. 2009 Aug 15;183(4):2729-40. doi: 10.4049/jimmunol.0804341. Epub 2009 Jul 20.

16.

Peptidylarginine Deiminase Inhibitor Suppresses Neutrophil Extracellular Trap Formation and MPO-ANCA Production.

Kusunoki Y, Nakazawa D, Shida H, Hattanda F, Miyoshi A, Masuda S, Nishio S, Tomaru U, Atsumi T, Ishizu A.

Front Immunol. 2016 Jun 8;7:227. doi: 10.3389/fimmu.2016.00227. eCollection 2016.

17.

Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies.

Liu CL, Tangsombatvisit S, Rosenberg JM, Mandelbaum G, Gillespie EC, Gozani OP, Alizadeh AA, Utz PJ.

Arthritis Res Ther. 2012 Feb 2;14(1):R25. doi: 10.1186/ar3707.

18.

Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction.

Furumoto Y, Smith CK, Blanco L, Zhao W, Brooks SR, Thacker SG, Abdalrahman Z, Sciumè G, Tsai WL, Trier AM, Nunez L, Mast L, Hoffmann V, Remaley AT, O'Shea JJ, Kaplan MJ, Gadina M.

Arthritis Rheumatol. 2017 Jan;69(1):148-160. doi: 10.1002/art.39818.

19.

Neutrophil-mediated IFN activation in the bone marrow alters B cell development in human and murine systemic lupus erythematosus.

Palanichamy A, Bauer JW, Yalavarthi S, Meednu N, Barnard J, Owen T, Cistrone C, Bird A, Rabinovich A, Nevarez S, Knight JS, Dedrick R, Rosenberg A, Wei C, Rangel-Moreno J, Liesveld J, Sanz I, Baechler E, Kaplan MJ, Anolik JH.

J Immunol. 2014 Feb 1;192(3):906-18. doi: 10.4049/jimmunol.1302112. Epub 2013 Dec 30.

20.

Neutrophil extracellular trap-associated protein activation of the NLRP3 inflammasome is enhanced in lupus macrophages.

Kahlenberg JM, Carmona-Rivera C, Smith CK, Kaplan MJ.

J Immunol. 2013 Feb 1;190(3):1217-26. doi: 10.4049/jimmunol.1202388. Epub 2012 Dec 24.

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