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Items: 1 to 20 of 193

1.

Axl/Gas6 pathway positively regulates FLT3 activation in human natural killer cell development.

Park IK, Trotta R, Yu J, Caligiuri MA.

Eur J Immunol. 2013 Oct;43(10):2750-5. doi: 10.1002/eji.201243116. Epub 2013 Jul 8.

2.

The Axl/Gas6 pathway is required for optimal cytokine signaling during human natural killer cell development.

Park IK, Giovenzana C, Hughes TL, Yu J, Trotta R, Caligiuri MA.

Blood. 2009 Mar 12;113(11):2470-7. doi: 10.1182/blood-2008-05-157073. Epub 2008 Oct 7.

3.

Flt3 ligand promotes the generation of a distinct CD34(+) human natural killer cell progenitor that responds to interleukin-15.

Yu H, Fehniger TA, Fuchshuber P, Thiel KS, Vivier E, Carson WE, Caligiuri MA.

Blood. 1998 Nov 15;92(10):3647-57.

4.
5.

Differentiation of NK1.1+, Ly49+ NK cells from flt3+ multipotent marrow progenitor cells.

Williams NS, Klem J, Puzanov IJ, Sivakumar PV, Bennett M, Kumar V.

J Immunol. 1999 Sep 1;163(5):2648-56.

6.

An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis.

Kariolis MS, Miao YR, Jones DS 2nd, Kapur S, Mathews II, Giaccia AJ, Cochran JR.

Nat Chem Biol. 2014 Nov;10(11):977-83. doi: 10.1038/nchembio.1636. Epub 2014 Sep 21.

7.

Axl signaling induces development of natural killer cells in vitro and in vivo.

Kim EM, Lee EH, Lee HY, Choi HR, Ji KY, Kim SM, Kim KD, Kang HS.

Protoplasma. 2017 Mar;254(2):1091-1101. doi: 10.1007/s00709-016-1016-5. Epub 2016 Aug 22.

PMID:
27549806
8.

Multi-level effects of flt3 ligand on human hematopoiesis: expansion of putative stem cells and proliferation of granulomonocytic progenitors/monocytic precursors.

Gabbianelli M, Pelosi E, Montesoro E, Valtieri M, Luchetti L, Samoggia P, Vitelli L, Barberi T, Testa U, Lyman S, et al.

Blood. 1995 Sep 1;86(5):1661-70.

9.

Expression of Flt3 and c-kit during growth and maturation of human CD34+CD38- cells.

Xiao M, Oppenlander BK, Plunkett JM, Dooley DC.

Exp Hematol. 1999 May;27(5):916-27.

PMID:
10340408
10.

Flt3 ligand and the Flt3 receptor regulate hematopoietic cell migration by modulating the SDF-1alpha(CXCL12)/CXCR4 axis.

Fukuda S, Broxmeyer HE, Pelus LM.

Blood. 2005 Apr 15;105(8):3117-26. Epub 2004 Dec 23.

11.

Expression of FLT3 receptor and response to FLT3 ligand by leukemic cells.

Drexler HG.

Leukemia. 1996 Apr;10(4):588-99. Review.

PMID:
8618433
12.

Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases.

Nagata K, Ohashi K, Nakano T, Arita H, Zong C, Hanafusa H, Mizuno K.

J Biol Chem. 1996 Nov 22;271(47):30022-7.

13.

A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death control.

Budagian V, Bulanova E, Orinska Z, Thon L, Mamat U, Bellosta P, Basilico C, Adam D, Paus R, Bulfone-Paus S.

EMBO J. 2005 Dec 21;24(24):4260-70. Epub 2005 Nov 24. Retraction in: EMBO J. 2011 Feb 2;30(3):627.

14.

Effect of flt3 ligand on the ex vivo expansion of human CD34+ hematopoietic progenitor cells.

McKenna HJ, de Vries P, Brasel K, Lyman SD, Williams DE.

Blood. 1995 Nov 1;86(9):3413-20.

15.

Inhibition of the receptor tyrosine kinase Axl impedes activation of the FLT3 internal tandem duplication in human acute myeloid leukemia: implications for Axl as a potential therapeutic target.

Park IK, Mishra A, Chandler J, Whitman SP, Marcucci G, Caligiuri MA.

Blood. 2013 Mar 14;121(11):2064-73. doi: 10.1182/blood-2012-07-444018. Epub 2013 Jan 15.

16.

Notch activation induces the generation of functional NK cells from human cord blood CD34-positive cells devoid of IL-15.

Haraguchi K, Suzuki T, Koyama N, Kumano K, Nakahara F, Matsumoto A, Yokoyama Y, Sakata-Yanagimoto M, Masuda S, Takahashi T, Kamijo A, Takahashi K, Takanashi M, Okuyama Y, Yasutomo K, Sakano S, Yagita H, Kurokawa M, Ogawa S, Chiba S.

J Immunol. 2009 May 15;182(10):6168-78. doi: 10.4049/jimmunol.0803036.

17.

The Notch ligands Jagged2, Delta1, and Delta4 induce differentiation and expansion of functional human NK cells from CD34+ cord blood hematopoietic progenitor cells.

Beck RC, Padival M, Yeh D, Ralston J, Cooke KR, Lowe JB.

Biol Blood Marrow Transplant. 2009 Sep;15(9):1026-37. doi: 10.1016/j.bbmt.2009.06.002.

19.

Flt3high and Flt3low CD34+ progenitor cells isolated from human bone marrow are functionally distinct.

Gotze KS, Ramirez M, Tabor K, Small D, Matthews W, Civin CI.

Blood. 1998 Mar 15;91(6):1947-58.

20.

Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling.

Pao-Chun L, Chan PM, Chan W, Manser E.

J Biol Chem. 2009 Dec 11;284(50):34954-63. doi: 10.1074/jbc.M109.072660. Epub 2009 Oct 8.

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