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Items: 1 to 20 of 87

1.

N-methylnitrosourea aggravates gastrointestinal polyposis in Lkb1+/- mice.

Udd L, Gao Y, Ristimäki AP, Mäkelä TP.

Carcinogenesis. 2013 Oct;34(10):2409-14. doi: 10.1093/carcin/bgt188. Epub 2013 May 30.

PMID:
23722652
2.

Suppression of Peutz-Jeghers polyposis by inhibition of cyclooxygenase-2.

Udd L, Katajisto P, Rossi DJ, Lepistö A, Lahesmaa AM, Ylikorkala A, Järvinen HJ, Ristimäki AP, Mäkelä TP.

Gastroenterology. 2004 Oct;127(4):1030-7.

PMID:
15480979
3.

Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis.

Rossi DJ, Ylikorkala A, Korsisaari N, Salovaara R, Luukko K, Launonen V, Henkemeyer M, Ristimaki A, Aaltonen LA, Makela TP.

Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12327-32. Epub 2002 Sep 6.

4.

Somatic mutations of LKB1 and beta-catenin genes in gastrointestinal polyps from patients with Peutz-Jeghers syndrome.

Miyaki M, Iijima T, Hosono K, Ishii R, Yasuno M, Mori T, Toi M, Hishima T, Shitara N, Tamura K, Utsunomiya J, Kobayashi N, Kuroki T, Iwama T.

Cancer Res. 2000 Nov 15;60(22):6311-3.

5.

Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice.

Miyoshi H, Nakau M, Ishikawa TO, Seldin MF, Oshima M, Taketo MM.

Cancer Res. 2002 Apr 15;62(8):2261-6.

6.

Identification of molecular alterations in gastrointestinal carcinomas and dysplastic hamartomas in Peutz-Jeghers syndrome.

Korsse SE, Biermann K, Offerhaus GJ, Wagner A, Dekker E, Mathus-Vliegen EM, Kuipers EJ, van Leerdam ME, van Veelen W.

Carcinogenesis. 2013 Jul;34(7):1611-9. doi: 10.1093/carcin/bgt068. Epub 2013 Feb 20.

PMID:
23430953
7.

Suppression of Peutz-Jeghers polyposis by targeting mammalian target of rapamycin signaling.

Wei C, Amos CI, Zhang N, Wang X, Rashid A, Walker CL, Behringer RR, Frazier ML.

Clin Cancer Res. 2008 Feb 15;14(4):1167-71. doi: 10.1158/1078-0432.CCR-07-4007.

8.

Nasal polyposis in Peutz-Jeghers syndrome: a distinct histopathological and molecular genetic entity.

de Leng WW, Westerman AM, Weterman MA, Jansen M, van Dekken H, Giardiello FM, de Rooij FW, Paul Wilson JH, Offerhaus GJ, Keller JJ.

J Clin Pathol. 2007 Apr;60(4):392-6. Epub 2006 Jun 14.

9.

Mutation of Lkb1 and p53 genes exert a cooperative effect on tumorigenesis.

Wei C, Amos CI, Stephens LC, Campos I, Deng JM, Behringer RR, Rashid A, Frazier ML.

Cancer Res. 2005 Dec 15;65(24):11297-303.

10.

Chemopreventive efficacy of rapamycin on Peutz-Jeghers syndrome in a mouse model.

Wei C, Amos CI, Zhang N, Zhu J, Wang X, Frazier ML.

Cancer Lett. 2009 May 18;277(2):149-54. doi: 10.1016/j.canlet.2008.11.036. Epub 2009 Jan 14.

11.

Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis.

Jishage K, Nezu J, Kawase Y, Iwata T, Watanabe M, Miyoshi A, Ose A, Habu K, Kake T, Kamada N, Ueda O, Kinoshita M, Jenne DE, Shimane M, Suzuki H.

Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8903-8. Epub 2002 Jun 11.

12.

[Peutz-Jeghers syndrome].

Miyaki M.

Nihon Rinsho. 2000 Jul;58(7):1400-4. Review. Japanese.

PMID:
10921312
13.

Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation.

Bardeesy N, Sinha M, Hezel AF, Signoretti S, Hathaway NA, Sharpless NE, Loda M, Carrasco DR, DePinho RA.

Nature. 2002 Sep 12;419(6903):162-7.

14.

Molecular genetic alterations in hamartomatous polyps and carcinomas of patients with Peutz-Jeghers syndrome.

Entius MM, Keller JJ, Westerman AM, van Rees BP, van Velthuysen ML, de Goeij AF, Wilson JH, Giardiello FM, Offerhaus GJ.

J Clin Pathol. 2001 Feb;54(2):126-31.

15.

Oral rapamycin reduces tumour burden and vascularization in Lkb1(+/-) mice.

Robinson J, Lai C, Martin A, Nye E, Tomlinson I, Silver A.

J Pathol. 2009 Sep;219(1):35-40. doi: 10.1002/path.2562.

PMID:
19434632
16.

Genetic screening for Peutz-Jeghers syndrome.

Ballhausen WG, Günther K.

Expert Rev Mol Diagn. 2003 Jul;3(4):471-9. Review.

PMID:
12877386
17.

Allelic imbalance at the LKB1 (STK11) locus in tumours from patients with Peutz-Jeghers' syndrome provides evidence for a hamartoma-(adenoma)-carcinoma sequence.

Wang ZJ, Ellis I, Zauber P, Iwama T, Marchese C, Talbot I, Xue WH, Yan ZY, Tomlinson I.

J Pathol. 1999 May;188(1):9-13.

PMID:
10398133
18.

Cancer risks in LKB1 germline mutation carriers.

Mehenni H, Resta N, Park JG, Miyaki M, Guanti G, Costanza MC.

Gut. 2006 Jul;55(7):984-90. Epub 2006 Jan 11.

19.

Mucosal prolapse in the pathogenesis of Peutz-Jeghers polyposis.

Jansen M, de Leng WW, Baas AF, Myoshi H, Mathus-Vliegen L, Taketo MM, Clevers H, Giardiello FM, Offerhaus GJ.

Gut. 2006 Jan;55(1):1-5.

20.

Impaired gastric gland differentiation in Peutz-Jeghers syndrome.

Udd L, Katajisto P, Kyyrönen M, Ristimäki AP, Mäkelä TP.

Am J Pathol. 2010 May;176(5):2467-76. doi: 10.2353/ajpath.2010.090519. Epub 2010 Apr 2.

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