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Items: 1 to 20 of 247

1.

Overexpression of Rab25 contributes to metastasis of bladder cancer through induction of epithelial-mesenchymal transition and activation of Akt/GSK-3β/Snail signaling.

Zhang J, Wei J, Lu J, Tong Z, Liao B, Yu B, Zheng F, Huang X, Chen Z, Fang Y, Li B, Chen W, Xie D, Luo J.

Carcinogenesis. 2013 Oct;34(10):2401-8. doi: 10.1093/carcin/bgt187. Epub 2013 May 30.

2.

CAV-1 contributes to bladder cancer progression by inducing epithelial-to-mesenchymal transition.

Liang W, Hao Z, Han JL, Zhu DJ, Jin ZF, Xie WL.

Urol Oncol. 2014 Aug;32(6):855-63. doi: 10.1016/j.urolonc.2014.01.005. Epub 2014 Jun 23.

PMID:
24968949
3.

PI3K/Akt to GSK3β/β-catenin signaling cascade coordinates cell colonization for bladder cancer bone metastasis through regulating ZEB1 transcription.

Wu K, Fan J, Zhang L, Ning Z, Zeng J, Zhou J, Li L, Chen Y, Zhang T, Wang X, Hsieh JT, He D.

Cell Signal. 2012 Dec;24(12):2273-82. doi: 10.1016/j.cellsig.2012.08.004. Epub 2012 Aug 18.

PMID:
22906492
4.

Phospho-Akt pathway activation and inhibition depends on N-cadherin or phospho-EGFR expression in invasive human bladder cancer cell lines.

Wallerand H, Cai Y, Wainberg ZA, Garraway I, Lascombe I, Nicolle G, Thiery JP, Bittard H, Radvanyi F, Reiter RR.

Urol Oncol. 2010 Mar-Apr;28(2):180-8. doi: 10.1016/j.urolonc.2008.09.041. Epub 2008 Dec 12.

PMID:
19070520
5.

CXCR2/CXCL5 axis contributes to epithelial-mesenchymal transition of HCC cells through activating PI3K/Akt/GSK-3β/Snail signaling.

Zhou SL, Zhou ZJ, Hu ZQ, Li X, Huang XW, Wang Z, Fan J, Dai Z, Zhou J.

Cancer Lett. 2015 Mar 28;358(2):124-35. doi: 10.1016/j.canlet.2014.11.044. Epub 2014 Nov 24.

PMID:
25462858
6.

Stabilization of Snail through AKT/GSK-3β signaling pathway is required for TNF-α-induced epithelial-mesenchymal transition in prostate cancer PC3 cells.

Wang H, Fang R, Wang XF, Zhang F, Chen DY, Zhou B, Wang HS, Cai SH, Du J.

Eur J Pharmacol. 2013 Aug 15;714(1-3):48-55. doi: 10.1016/j.ejphar.2013.05.046. Epub 2013 Jun 11.

PMID:
23769744
7.

Epithelial-mesenchymal transition (EMT) induced by TNF-α requires AKT/GSK-3β-mediated stabilization of snail in colorectal cancer.

Wang H, Wang HS, Zhou BH, Li CL, Zhang F, Wang XF, Zhang G, Bu XZ, Cai SH, Du J.

PLoS One. 2013;8(2):e56664. doi: 10.1371/journal.pone.0056664. Epub 2013 Feb 19.

8.

Antiproliferative factor decreases Akt phosphorylation and alters gene expression via CKAP4 in T24 bladder carcinoma cells.

Shahjee HM, Koch KR, Guo L, Zhang CO, Keay SK.

J Exp Clin Cancer Res. 2010 Dec 10;29:160. doi: 10.1186/1756-9966-29-160.

9.

Involvement of Pin1 induction in epithelial-mesenchymal transition of tamoxifen-resistant breast cancer cells.

Kim MR, Choi HK, Cho KB, Kim HS, Kang KW.

Cancer Sci. 2009 Oct;100(10):1834-41. doi: 10.1111/j.1349-7006.2009.01260.x. Epub 2009 Jul 24.

10.

AKT/GSK-3β regulates stability and transcription of snail which is crucial for bFGF-induced epithelial-mesenchymal transition of prostate cancer cells.

Liu ZC, Wang HS, Zhang G, Liu H, Chen XH, Zhang F, Chen DY, Cai SH, Du J.

Biochim Biophys Acta. 2014 Oct;1840(10):3096-105. doi: 10.1016/j.bbagen.2014.07.018. Epub 2014 Aug 1.

PMID:
25088797
11.

Glycogen synthase kinase-3 beta regulates Snail and β-catenin expression during Fas-induced epithelial-mesenchymal transition in gastrointestinal cancer.

Zheng H, Li W, Wang Y, Liu Z, Cai Y, Xie T, Shi M, Wang Z, Jiang B.

Eur J Cancer. 2013 Aug;49(12):2734-46. doi: 10.1016/j.ejca.2013.03.014. Epub 2013 Apr 9.

PMID:
23582741
12.

Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer.

Guo BH, Feng Y, Zhang R, Xu LH, Li MZ, Kung HF, Song LB, Zeng MS.

Mol Cancer. 2011 Jan 28;10(1):10. doi: 10.1186/1476-4598-10-10.

13.

TNF-α induces epithelial-mesenchymal transition of renal cell carcinoma cells via a GSK3β-dependent mechanism.

Ho MY, Tang SJ, Chuang MJ, Cha TL, Li JY, Sun GH, Sun KH.

Mol Cancer Res. 2012 Aug;10(8):1109-19. doi: 10.1158/1541-7786.MCR-12-0160. Epub 2012 Jun 15.

14.

EIF5A2 predicts outcome in localised invasive bladder cancer and promotes bladder cancer cell aggressiveness in vitro and in vivo.

Wei JH, Cao JZ, Zhang D, Liao B, Zhong WM, Lu J, Zhao HW, Zhang JX, Tong ZT, Fan S, Liang CZ, Liao YB, Pang J, Wu RH, Fang Y, Chen ZH, Li B, Xie D, Chen W, Luo JH.

Br J Cancer. 2014 Apr 2;110(7):1767-77. doi: 10.1038/bjc.2014.52. Epub 2014 Feb 6.

15.

Acquisition of EMT phenotype in the gefitinib-resistant cells of a head and neck squamous cell carcinoma cell line through Akt/GSK-3β/snail signalling pathway.

Maseki S, Ijichi K, Tanaka H, Fujii M, Hasegawa Y, Ogawa T, Murakami S, Kondo E, Nakanishi H.

Br J Cancer. 2012 Mar 13;106(6):1196-204. doi: 10.1038/bjc.2012.24. Epub 2012 Feb 7.

16.

Slug contributes to cadherin switch and malignant progression in muscle-invasive bladder cancer development.

Wu K, Zeng J, Zhou J, Fan J, Chen Y, Wang Z, Zhang T, Wang X, He D.

Urol Oncol. 2013 Nov;31(8):1751-60. doi: 10.1016/j.urolonc.2012.02.001. Epub 2012 Mar 14.

PMID:
22421353
17.

Glycogen synthase kinase-3beta: a prognostic marker and a potential therapeutic target in human bladder cancer.

Naito S, Bilim V, Yuuki K, Ugolkov A, Motoyama T, Nagaoka A, Kato T, Tomita Y.

Clin Cancer Res. 2010 Nov 1;16(21):5124-32. doi: 10.1158/1078-0432.CCR-10-0275. Epub 2010 Oct 1.

18.

miR-208-induced epithelial to mesenchymal transition of pancreatic cancer cells promotes cell metastasis and invasion.

Liu A, Shao C, Jin G, Liu R, Hao J, Song B, Ouyang L, Hu X.

Cell Biochem Biophys. 2014 Jun;69(2):341-6. doi: 10.1007/s12013-013-9805-3.

PMID:
24604208
19.

Blocking PI3K/Akt signaling attenuates metastasis of nasopharyngeal carcinoma cells through induction of mesenchymal-epithelial reverting transition.

Jiang H, Gao M, Shen Z, Luo B, Li R, Jiang X, Ding R, Ha Y, Wang Z, Jie W.

Oncol Rep. 2014 Aug;32(2):559-66. doi: 10.3892/or.2014.3220. Epub 2014 May 29.

PMID:
24889918
20.

Identification of a GαGβγ, AKT and PKCα signalome associated with invasive growth in two genetic models of human breast cancer cell epithelial-to-mesenchymal transition.

Ouelaa-Benslama R, De Wever O, Hendrix A, Sabbah M, Lambein K, Land D, Prévost G, Bracke M, Hung MC, Larsen AK, Emami S, Gespach C.

Int J Oncol. 2012 Jul;41(1):189-200. doi: 10.3892/ijo.2012.1457. Epub 2012 Apr 30.

PMID:
22552300
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